ENSG00000075131


Homo sapiens

Features
Gene ID: ENSG00000075131
  
Biological name :TIPIN
  
Synonyms : Q9BVW5 / TIMELESS interacting protein / TIPIN
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 15
Strand: -1
Band: q22.31
Gene start: 66336206
Gene end: 66386746
  
Corresponding Affymetrix probe sets: 219258_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000455656
Ensembl peptide - ENSP00000457406
Ensembl peptide - ENSP00000458117
Ensembl peptide - ENSP00000261881
Ensembl peptide - ENSP00000457172
NCBI entrez gene - 54962     See in Manteia.
OMIM - 610716
RefSeq - XM_017022391
RefSeq - NM_001289986
RefSeq - NM_017858
RefSeq - XM_005254521
RefSeq - XM_005254522
RefSeq - XM_006720594
RefSeq - XM_011521743
RefSeq - XM_017022390
RefSeq Peptide - NP_001276915
RefSeq Peptide - NP_060328
swissprot - H3BVG9
swissprot - H3BTH1
swissprot - H3BQ83
swissprot - Q9BVW5
swissprot - H3BU04
Ensembl - ENSG00000075131
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tipinENSDARG00000036136Danio rerio
 TIPINENSGALG00000007649Gallus gallus
 TipinENSMUSG00000032397Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR012923  Chromosome segregation in meiosis protein 3


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000076 DNA replication checkpoint IMP
 biological_processGO:0000077 DNA damage checkpoint IEA
 biological_processGO:0006260 DNA replication TAS
 biological_processGO:0006974 cellular response to DNA damage stimulus IEA
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0008284 positive regulation of cell proliferation IMP
 biological_processGO:0009411 response to UV IEA
 biological_processGO:0031573 intra-S DNA damage checkpoint IMP
 biological_processGO:0033262 regulation of nuclear cell cycle DNA replication TAS
 biological_processGO:0043111 replication fork arrest IBA
 biological_processGO:0044770 cell cycle phase transition IMP
 biological_processGO:0048478 replication fork protection IEA
 biological_processGO:0051301 cell division IEA
 cellular_componentGO:0000790 nuclear chromatin IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0031298 replication fork protection complex IBA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IDA
 molecular_functionGO:0003677 DNA binding IBA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Processing of DNA double-strand break ends


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000092853 CLSPN / Q9HAW4 / claspin  / reaction
 ENSG00000149554 CHEK1 / O14757 / checkpoint kinase 1  / reaction
 ENSG00000111602 Q9UNS1 / TIMELESS / timeless circadian regulator  / complex






 

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