ENSG00000075218


Homo sapiens

Features
Gene ID: ENSG00000075218
  
Biological name :GTSE1
  
Synonyms : G2 and S-phase expressed 1 / GTSE1 / Q9NYZ3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 22
Strand: 1
Band: q13.31
Gene start: 46296741
Gene end: 46330810
  
Corresponding Affymetrix probe sets: 204315_s_at (Human Genome U133 Plus 2.0 Array)   204318_s_at (Human Genome U133 Plus 2.0 Array)   211040_x_at (Human Genome U133 Plus 2.0 Array)   215942_s_at (Human Genome U133 Plus 2.0 Array)   229343_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000415430
NCBI entrez gene - 51512     See in Manteia.
OMIM - 607477
RefSeq - XM_017028816
RefSeq - NM_016426
RefSeq - XM_011530211
RefSeq - XM_017028815
RefSeq - XM_005261627
RefSeq Peptide - NP_057510
swissprot - Q9NYZ3
Ensembl - ENSG00000075218
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gtse1ENSDARG00000013719Danio rerio
 GTSE1ENSGALG00000004897Gallus gallus
 Gtse1ENSMUSG00000022385Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR026657  Proline/serine-rich coiled-coil protein 1/G2 and S phase-expressed protein 1
 IPR026659  G2 and S phase-expressed protein 1
 IPR032768  G2 and S phase-expressed protein 1, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest NAS
 biological_processGO:0007017 microtubule-based process NAS
 biological_processGO:0030335 positive regulation of cell migration TAS
 biological_processGO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process TAS
 biological_processGO:0046827 positive regulation of protein export from nucleus TAS
 biological_processGO:0050821 protein stabilization TAS
 biological_processGO:1900182 positive regulation of protein localization to nucleus TAS
 biological_processGO:1902749 regulation of cell cycle G2/M phase transition TAS
 biological_processGO:1904527 negative regulation of microtubule binding TAS
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005874 microtubule IEA
 cellular_componentGO:0005881 cytoplasmic microtubule IDA
 cellular_componentGO:0016020 membrane HDA
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
G2/M Checkpoints
The role of GTSE1 in G2/M progression after G2 checkpoint


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000141510 TP53 / P04637 / tumor protein p53  / complex / reaction
 ENSG00000096384 P08238 / HSP90AB1 / heat shock protein 90 alpha family class B member 1  / complex / reaction
 ENSG00000124762 CDKN1A / P38936 / cyclin dependent kinase inhibitor 1A  / complex / reaction
 ENSG00000166851 PLK1 / P53350 / polo like kinase 1  / reaction / complex
 ENSG00000080824 P07900 / HSP90AA1 / heat shock protein 90 alpha family class A member 1  / complex / reaction
 ENSG00000204315 FKBPL / Q9UIM3 / FK506 binding protein like  / complex / reaction
 ENSG00000101367 MAPRE1 / Q15691 / microtubule associated protein RP/EB family member 1  / reaction / complex






 

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