ENSG00000075340


Homo sapiens

Features
Gene ID: ENSG00000075340
  
Biological name :ADD2
  
Synonyms : ADD2 / adducin 2 / P35612
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: -1
Band: p13.3
Gene start: 70607618
Gene end: 70768225
  
Corresponding Affymetrix probe sets: 205268_s_at (Human Genome U133 Plus 2.0 Array)   206807_s_at (Human Genome U133 Plus 2.0 Array)   213484_at (Human Genome U133 Plus 2.0 Array)   230988_at (Human Genome U133 Plus 2.0 Array)   237336_at (Human Genome U133 Plus 2.0 Array)   239530_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000388072
Ensembl peptide - ENSP00000398112
Ensembl peptide - ENSP00000430243
Ensembl peptide - ENSP00000414546
Ensembl peptide - ENSP00000412681
Ensembl peptide - ENSP00000412357
Ensembl peptide - ENSP00000403722
Ensembl peptide - ENSP00000264436
Ensembl peptide - ENSP00000347972
Ensembl peptide - ENSP00000384303
Ensembl peptide - ENSP00000384677
NCBI entrez gene - 119     See in Manteia.
OMIM - 102681
RefSeq - XM_011532502
RefSeq - NM_001185054
RefSeq - NM_001185055
RefSeq - NM_001617
RefSeq - NM_017482
RefSeq - NM_017488
RefSeq Peptide - NP_001608
RefSeq Peptide - NP_059522
RefSeq Peptide - NP_001171983
RefSeq Peptide - NP_001171984
RefSeq Peptide - NP_059516
swissprot - A0A1C7CYY0
swissprot - C9JJK3
swissprot - C9J299
swissprot - P35612
swissprot - C9JTM0
swissprot - C9J080
Ensembl - ENSG00000075340
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 add2ENSDARG00000074581Danio rerio
 ADD2ENSGALG00000026948Gallus gallus
 Add2ENSMUSG00000030000Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ADD3 / Q9UEY8 / adducin 3ENSG0000014870052
ADD1 / P35611 / adducin 1ENSG0000008727447


Protein motifs (from Interpro)
Interpro ID Name
 IPR001303  Class II aldolase/adducin N-terminal
 IPR027773  Beta-adducin
 IPR036409  Class II aldolase/adducin N-terminal domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0030036 actin cytoskeleton organization IC
 biological_processGO:0030097 hemopoiesis IEA
 biological_processGO:0032092 positive regulation of protein binding IDA
 biological_processGO:0050900 leukocyte migration IMP
 biological_processGO:0050901 leukocyte tethering or rolling IMP
 biological_processGO:0051016 barbed-end actin filament capping IDA
 biological_processGO:0051017 actin filament bundle assembly IDA
 biological_processGO:0055085 transmembrane transport TAS
 biological_processGO:0065003 protein-containing complex assembly IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0008290 F-actin capping protein complex IDA
 cellular_componentGO:0014069 postsynaptic density IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IDA
 cellular_componentGO:0044853 plasma membrane raft IMP
 molecular_functionGO:0003779 actin binding IMP
 molecular_functionGO:0005198 structural molecule activity IEA
 molecular_functionGO:0005516 calmodulin binding IEA
 molecular_functionGO:0019901 protein kinase binding IPI
 molecular_functionGO:0030507 spectrin binding IDA
 molecular_functionGO:0042803 protein homodimerization activity IPI
 molecular_functionGO:0046982 protein heterodimerization activity IPI
 molecular_functionGO:0051015 actin filament binding IDA


Pathways (from Reactome)
Pathway description
Miscellaneous transport and binding events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000158856 DMTN / Q08495 / dematin actin binding protein  / reaction / complex
 ENSG00000087274 ADD1 / P35611 / adducin 1  / complex






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr