ENSG00000075426


Homo sapiens

Features
Gene ID: ENSG00000075426
  
Biological name :FOSL2
  
Synonyms : FOSL2 / FOS like 2, AP-1 transcription factor subunit / P15408
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: 1
Band: p23.2
Gene start: 28392448
Gene end: 28417312
  
Corresponding Affymetrix probe sets: 205409_at (Human Genome U133 Plus 2.0 Array)   218880_at (Human Genome U133 Plus 2.0 Array)   218881_s_at (Human Genome U133 Plus 2.0 Array)   225262_at (Human Genome U133 Plus 2.0 Array)   228188_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000396497
Ensembl peptide - ENSP00000264716
Ensembl peptide - ENSP00000368939
NCBI entrez gene - 2355     See in Manteia.
OMIM - 601575
RefSeq - XM_017003737
RefSeq - NM_005253
RefSeq - XM_005264231
RefSeq - XM_006711976
RefSeq - XM_006711977
RefSeq Peptide - NP_005244
swissprot - P15408
swissprot - C9JCN8
Ensembl - ENSG00000075426
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 fosl2ENSDARG00000040623Danio rerio
 FOSL2ENSGALG00000010036Gallus gallus
 Fosl2ENSMUSG00000029135Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
FOS / P01100 / Fos proto-oncogene, AP-1 transcription factor subunitENSG0000017034547
FOSL1 / P15407 / FOS like 1, AP-1 transcription factor subunitENSG0000017559241
FOSB / P53539 / FosB proto-oncogene, AP-1 transcription factor subunitENSG0000012574040


Protein motifs (from Interpro)
Interpro ID Name
 IPR000837  AP-1 transcription factor
 IPR004827  Basic-leucine zipper domain
 IPR029814  Fos-related antigen 2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0003334 keratinocyte development IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0008219 cell death TAS
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0048146 positive regulation of fibroblast proliferation IEA
 cellular_componentGO:0005634 nucleus TAS
 cellular_componentGO:0005654 nucleoplasm IDA
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding IDA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003682 chromatin binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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