ENSG00000175592


Homo sapiens

Features
Gene ID: ENSG00000175592
  
Biological name :FOSL1
  
Synonyms : FOSL1 / FOS like 1, AP-1 transcription factor subunit / P15407
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: -1
Band: q13.1
Gene start: 65892049
Gene end: 65900573
  
Corresponding Affymetrix probe sets: 204420_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000436276
Ensembl peptide - ENSP00000431594
Ensembl peptide - ENSP00000310170
Ensembl peptide - ENSP00000393302
Ensembl peptide - ENSP00000434350
NCBI entrez gene - 8061     See in Manteia.
OMIM - 136515
RefSeq - NM_001300844
RefSeq - NM_001300855
RefSeq - NM_001300856
RefSeq - NM_001300857
RefSeq - NM_005438
RefSeq Peptide - NP_001287785
RefSeq Peptide - NP_001287786
RefSeq Peptide - NP_005429
RefSeq Peptide - NP_001287773
RefSeq Peptide - NP_001287784
swissprot - A0A0S2Z595
swissprot - E9PQT6
swissprot - E9PPX2
swissprot - P15407
swissprot - E9PKL5
Ensembl - ENSG00000175592
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 fosl1aENSDARG00000015355Danio rerio
 Fosl1ENSMUSG00000024912Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
FOSL2 / P15408 / FOS like 2, AP-1 transcription factor subunitENSG0000007542649
FOS / P01100 / Fos proto-oncogene, AP-1 transcription factor subunitENSG0000017034545
FOSB / P53539 / FosB proto-oncogene, AP-1 transcription factor subunitENSG0000012574040


Protein motifs (from Interpro)
Interpro ID Name
 IPR000837  AP-1 transcription factor
 IPR004827  Basic-leucine zipper domain
 IPR029815  Fos-related antigen 1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001701 in utero embryonic development IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006366 transcription by RNA polymerase II TAS
 biological_processGO:0006935 chemotaxis TAS
 biological_processGO:0006968 cellular defense response TAS
 biological_processGO:0007296 vitellogenesis IEA
 biological_processGO:0007565 female pregnancy IEA
 biological_processGO:0007612 learning IEA
 biological_processGO:0008284 positive regulation of cell proliferation TAS
 biological_processGO:0008285 negative regulation of cell proliferation IEA
 biological_processGO:0009612 response to mechanical stimulus IEA
 biological_processGO:0009615 response to virus TAS
 biological_processGO:0009629 response to gravity IEA
 biological_processGO:0014070 response to organic cyclic compound IEA
 biological_processGO:0031668 cellular response to extracellular stimulus IEA
 biological_processGO:0032570 response to progesterone IEA
 biological_processGO:0034097 response to cytokine IEA
 biological_processGO:0042493 response to drug IEA
 biological_processGO:0042542 response to hydrogen peroxide IEA
 biological_processGO:0043065 positive regulation of apoptotic process IEA
 biological_processGO:0045787 positive regulation of cell cycle IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0051091 positive regulation of DNA-binding transcription factor activity IEA
 biological_processGO:0051412 response to corticosterone IEA
 biological_processGO:0051591 response to cAMP IEA
 biological_processGO:0060674 placenta blood vessel development IEA
 biological_processGO:0061614 pri-miRNA transcription by RNA polymerase II IDA
 biological_processGO:2000144 positive regulation of DNA-templated transcription, initiation IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0042734 presynaptic membrane IEA
 cellular_componentGO:0043005 neuron projection IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IEA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IDA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0001077 transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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