ENSG00000080166


Homo sapiens

Features
Gene ID: ENSG00000080166
  
Biological name :DCT
  
Synonyms : DCT / dopachrome tautomerase / P40126
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 13
Strand: -1
Band: q32.1
Gene start: 94436808
Gene end: 94479682
  
Corresponding Affymetrix probe sets: 205337_at (Human Genome U133 Plus 2.0 Array)   205338_s_at (Human Genome U133 Plus 2.0 Array)   216512_s_at (Human Genome U133 Plus 2.0 Array)   216513_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000366227
Ensembl peptide - ENSP00000392762
Ensembl peptide - ENSP00000431275
NCBI entrez gene - 1638     See in Manteia.
OMIM - 191275
RefSeq - NM_001322186
RefSeq - NM_001922
RefSeq - XM_017020401
RefSeq - NM_001129889
RefSeq - NM_001322182
RefSeq - NM_001322184
RefSeq - NM_001322185
RefSeq - XM_011521049
RefSeq Peptide - NP_001123361
RefSeq Peptide - NP_001309113
RefSeq Peptide - NP_001309114
RefSeq Peptide - NP_001309115
RefSeq Peptide - NP_001913
RefSeq Peptide - NP_001309111
swissprot - A0A0A0MTD3
swissprot - P40126
Ensembl - ENSG00000080166
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dctENSDARG00000006008Danio rerio
 DCTENSGALG00000016899Gallus gallus
 DctENSMUSG00000022129Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
TYRP1 / P17643 / tyrosinase related protein 1ENSG0000010716545
TYR / P14679 / tyrosinaseENSG0000007749837


Protein motifs (from Interpro)
Interpro ID Name
 IPR002227  Tyrosinase copper-binding domain
 IPR008922  Uncharacterised domain, di-copper centre


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002052 positive regulation of neuroblast proliferation IEA
 biological_processGO:0006583 melanin biosynthetic process from tyrosine IEA
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0008544 epidermis development TAS
 biological_processGO:0021847 ventricular zone neuroblast division IEA
 biological_processGO:0042438 melanin biosynthetic process TAS
 biological_processGO:0043473 pigmentation IEA
 biological_processGO:0048066 developmental pigmentation IEA
 biological_processGO:0048468 cell development IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane TAS
 cellular_componentGO:0033162 melanosome membrane TAS
 cellular_componentGO:0042470 melanosome ISS
 molecular_functionGO:0004167 dopachrome isomerase activity ISS
 molecular_functionGO:0005507 copper ion binding TAS
 molecular_functionGO:0016491 oxidoreductase activity TAS
 molecular_functionGO:0016853 isomerase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Melanin biosynthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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