ENSG00000083454


Homo sapiens

Features
Gene ID: ENSG00000083454
  
Biological name :P2RX5
  
Synonyms : P2RX5 / purinergic receptor P2X 5 / Q93086
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: -1
Band: p13.2
Gene start: 3672199
Gene end: 3696404
  
Corresponding Affymetrix probe sets: 210448_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000450006
Ensembl peptide - ENSP00000342161
Ensembl peptide - ENSP00000225328
Ensembl peptide - ENSP00000449495
Ensembl peptide - ENSP00000467707
Ensembl peptide - ENSP00000447545
Ensembl peptide - ENSP00000447815
Ensembl peptide - ENSP00000448355
NCBI entrez gene - 5026     See in Manteia.
OMIM - 602836
RefSeq - NM_175080
RefSeq - NM_001204519
RefSeq - NM_001204520
RefSeq - NM_002561
RefSeq Peptide - NP_001191448
RefSeq Peptide - NP_778255
RefSeq Peptide - NP_002552
RefSeq Peptide - NP_001191449
swissprot - Q93086
swissprot - B4DEG2
swissprot - H0YHT9
swissprot - H0YII8
swissprot - K7EQ78
Ensembl - ENSG00000083454
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 p2rx5ENSDARG00000004455Danio rerio
 p2rx8ENSDARG00000024139Danio rerio
 P2RX5ENSGALG00000004613Gallus gallus
 P2rx5ENSMUSG00000005950Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P2RX5-TAX1BP3 / P2RX5-TAX1BP3 readthrough (NMD candidate)ENSG00000257950100
P2RX4 / Q99571 / purinergic receptor P2X 4ENSG0000013512445
P2RX6 / O15547 / purinergic receptor P2X 6ENSG0000009995742
P2RX3 / P56373 / purinergic receptor P2X 3ENSG0000010999138
P2RX2 / Q9UBL9 / purinergic receptor P2X 2ENSG0000018784838
P2RX1 / P51575 / purinergic receptor P2X 1ENSG0000010840538
P2RX7 / Q99572 / purinergic receptor P2X 7ENSG0000008904133


Protein motifs (from Interpro)
Interpro ID Name
 IPR001429  P2X purinoreceptor
 IPR003048  P2X5 purinoceptor
 IPR027309  P2X purinoreceptor extracellular domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0007165 signal transduction TAS
 biological_processGO:0007399 nervous system development TAS
 biological_processGO:0007596 blood coagulation TAS
 biological_processGO:0010524 positive regulation of calcium ion transport into cytosol NAS
 biological_processGO:0033198 response to ATP IEA
 biological_processGO:0035590 purinergic nucleotide receptor signaling pathway IEA
 biological_processGO:0050850 positive regulation of calcium-mediated signaling NAS
 biological_processGO:0060079 excitatory postsynaptic potential IEA
 biological_processGO:0098655 cation transmembrane transport IEA
 cellular_componentGO:0005639 integral component of nuclear inner membrane IBA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0098794 postsynapse IEA
 molecular_functionGO:0001614 purinergic nucleotide receptor activity IEA
 molecular_functionGO:0004888 transmembrane signaling receptor activity TAS
 molecular_functionGO:0004931 extracellularly ATP-gated cation channel activity IEA
 molecular_functionGO:0005216 ion channel activity IEA
 molecular_functionGO:0005524 ATP binding IEA


Pathways (from Reactome)
Pathway description
Elevation of cytosolic Ca2+ levels
Platelet homeostasis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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