ENSG00000085721


Homo sapiens

Features
Gene ID: ENSG00000085721
  
Biological name :RRN3
  
Synonyms : Q9NYV6 / RRN3 / RRN3 homolog, RNA polymerase I transcription factor
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 16
Strand: -1
Band: p13.11
Gene start: 15060022
Gene end: 15094317
  
Corresponding Affymetrix probe sets: 216902_s_at (Human Genome U133 Plus 2.0 Array)   216908_x_at (Human Genome U133 Plus 2.0 Array)   222204_s_at (Human Genome U133 Plus 2.0 Array)   230328_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000318484
Ensembl peptide - ENSP00000454238
Ensembl peptide - ENSP00000454530
Ensembl peptide - ENSP00000198767
Ensembl peptide - ENSP00000402027
NCBI entrez gene - 54700     See in Manteia.
OMIM - 605121
RefSeq - XM_011522541
RefSeq - NM_001301064
RefSeq - NM_018427
RefSeq - XM_005255376
RefSeq - XM_005255377
RefSeq - XM_011522540
RefSeq Peptide - NP_001287993
RefSeq Peptide - NP_060897
swissprot - H3BMT1
swissprot - Q9NYV6
swissprot - F5H148
Ensembl - ENSG00000085721
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rrn3ENSDARG00000102997Danio rerio
 RRN3ENSGALG00000041989Gallus gallus
 Rrn3ENSMUSG00000022682Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR007991  RNA polymerase I specific transcription initiation factor RRN3
 IPR011989  Armadillo-like helical


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001188 RNA polymerase I transcriptional preinitiation complex assembly IEA
 biological_processGO:0001701 in utero embryonic development IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006352 DNA-templated transcription, initiation IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006356 regulation of transcription by RNA polymerase I IEA
 biological_processGO:0006361 transcription initiation from RNA polymerase I promoter TAS
 biological_processGO:0007000 nucleolus organization IEA
 biological_processGO:0007028 cytoplasm organization IEA
 biological_processGO:0008283 cell proliferation IEA
 biological_processGO:0010976 positive regulation of neuron projection development IEA
 biological_processGO:0042254 ribosome biogenesis IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IEA
 biological_processGO:0048872 homeostasis of number of cells IEA
 biological_processGO:1902254 negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator IEA
 biological_processGO:2000142 regulation of DNA-templated transcription, initiation IEA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005730 nucleolus IEA
 molecular_functionGO:0001042 RNA polymerase I core binding IBA
 molecular_functionGO:0001164 RNA polymerase I CORE element sequence-specific DNA binding IDA
 molecular_functionGO:0001181 RNA polymerase I general transcription initiation factor activity IBA
 molecular_functionGO:0070063 RNA polymerase binding IEA


Pathways (from Reactome)
Pathway description
RNA Polymerase I Transcription Initiation
RNA Polymerase I Promoter Escape


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000108312 UBTF / P17480 / upstream binding transcription factor, RNA polymerase I  / reaction / complex






 

1 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr