ENSG00000086967


Homo sapiens

Features
Gene ID: ENSG00000086967
  
Biological name :MYBPC2
  
Synonyms : MYBPC2 / myosin binding protein C, fast type / Q14324
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: 1
Band: q13.33
Gene start: 50432903
Gene end: 50466321
  
Corresponding Affymetrix probe sets: 206394_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000350332
NCBI entrez gene - 4606     See in Manteia.
OMIM - 160793
RefSeq - NM_004533
RefSeq Peptide - NP_004524
swissprot - A0A140VJQ0
swissprot - Q14324
Ensembl - ENSG00000086967
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mybpc2aENSDARG00000030157Danio rerio
 mybpc2bENSDARG00000021265Danio rerio
 Mybpc2ENSMUSG00000038670Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MYBPC3 / Q14896 / myosin binding protein C, cardiacENSG0000013457155
MYBPC1 / Q00872 / myosin binding protein C, slow typeENSG0000019609150
IGSF22 / Q8N9C0 / immunoglobulin superfamily member 22ENSG0000017905727
IGFN1 / Q86VF2 / immunoglobulin-like and fibronectin type III domain containing 1ENSG0000016339527
MYBPH / Q13203 / myosin binding protein HENSG0000013305521
MYOM1 / P52179 / myomesin 1ENSG0000010160520
MYOM2 / P54296 / myomesin 2ENSG0000003644817
MYOM3 / Q5VTT5 / myomesin 3ENSG0000014266116
A2RUH7 / MYBPHL / myosin binding protein H likeENSG0000022198615


Protein motifs (from Interpro)
Interpro ID Name
 IPR003598  Immunoglobulin subtype 2
 IPR003599  Immunoglobulin subtype
 IPR003961  Fibronectin type III
 IPR007110  Immunoglobulin-like domain
 IPR013098  Immunoglobulin I-set
 IPR013783  Immunoglobulin-like fold
 IPR036116  Fibronectin type III superfamily
 IPR036179  Immunoglobulin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006936 muscle contraction IEA
 biological_processGO:0006941 striated muscle contraction IBA
 biological_processGO:0007015 actin filament organization IBA
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0030049 muscle filament sliding TAS
 biological_processGO:0045214 sarcomere organization IBA
 biological_processGO:0071688 striated muscle myosin thick filament assembly IBA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005859 muscle myosin complex IBA
 cellular_componentGO:0030018 Z disc IBA
 cellular_componentGO:0031430 M band IBA
 cellular_componentGO:0032982 myosin filament IEA
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008307 structural constituent of muscle TAS
 molecular_functionGO:0051015 actin filament binding IBA
 molecular_functionGO:0051371 muscle alpha-actinin binding IBA
 molecular_functionGO:0097493 structural molecule activity conferring elasticity IBA


Pathways (from Reactome)
Pathway description
Striated Muscle Contraction


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000111245 MYL2 / P10916 / myosin light chain 2  / complex
 ENSG00000160808 MYL3 / P08590 / myosin light chain 3  / complex
 ENSG00000168530 MYL1 / P05976 / myosin light chain 1  / complex
 ENSG00000198336 MYL4 / P12829 / myosin light chain 4  / complex
 ENSG00000109063 MYH3 / P11055 / myosin heavy chain 3  / complex / reaction
 ENSG00000133020 MYH8 / P13535 / myosin heavy chain 8  / complex / reaction
 ENSG00000197616 MYH6 / P13533 / myosin heavy chain 6  / complex / reaction
 ENSG00000155657 TTN / titin / Q8WZ42  / complex






 

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