ENSG00000168530


Homo sapiens

Features
Gene ID: ENSG00000168530
  
Biological name :MYL1
  
Synonyms : MYL1 / myosin light chain 1 / P05976
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: -1
Band: q34
Gene start: 210290150
Gene end: 210315190
  
Corresponding Affymetrix probe sets: 209888_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000307280
Ensembl peptide - ENSP00000343321
NCBI entrez gene - 4632     See in Manteia.
OMIM - 160780
RefSeq - NM_079420
RefSeq - NM_079422
RefSeq Peptide - NP_524144
RefSeq Peptide - NP_524146
swissprot - P05976
Ensembl - ENSG00000168530
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 myl1ENSDARG00000014196Danio rerio
 mylz3ENSDARG00000017441Danio rerio
 MYL1ENSGALG00000002907Gallus gallus
 Myl1ENSMUSG00000061816Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MYL3 / P08590 / myosin light chain 3ENSG0000016080873
MYL4 / P12829 / myosin light chain 4ENSG0000019833672
MYL6B / P14649 / myosin light chain 6BENSG0000019646566
MYL6 / P60660 / myosin light chain 6ENSG0000009284157


Protein motifs (from Interpro)
Interpro ID Name
 IPR002048  EF-hand domain
 IPR011992  EF-hand domain pair


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006936 muscle contraction IDA
 biological_processGO:0030049 muscle filament sliding NAS
 biological_processGO:0060048 cardiac muscle contraction IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005859 muscle myosin complex NAS
 cellular_componentGO:0016459 myosin complex IEA
 cellular_componentGO:0030016 myofibril IDA
 cellular_componentGO:0030017 sarcomere NAS
 cellular_componentGO:0043292 contractile fiber IEA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0008307 structural constituent of muscle NAS


Pathways (from Reactome)
Pathway description
Striated Muscle Contraction


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000111245 MYL2 / P10916 / myosin light chain 2  / complex
 ENSG00000134571 MYBPC3 / Q14896 / myosin binding protein C, cardiac  / complex
 ENSG00000160808 MYL3 / P08590 / myosin light chain 3  / complex
 ENSG00000168530 MYL1 / P05976 / myosin light chain 1  / complex
 ENSG00000155657 TTN / titin / Q8WZ42  / complex
 ENSG00000086967 MYBPC2 / Q14324 / myosin binding protein C, fast type  / complex
 ENSG00000196091 MYBPC1 / Q00872 / myosin binding protein C, slow type  / complex
 ENSG00000198336 MYL4 / P12829 / myosin light chain 4  / complex
 ENSG00000197616 MYH6 / P13533 / myosin heavy chain 6  / reaction / complex
 ENSG00000133020 MYH8 / P13535 / myosin heavy chain 8  / reaction / complex
 ENSG00000109063 MYH3 / P11055 / myosin heavy chain 3  / reaction / complex






 

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