ENSG00000087087


Homo sapiens

Features
Gene ID: ENSG00000087087
  
Biological name :SRRT
  
Synonyms : Q9BXP5 / serrate, RNA effector molecule / SRRT
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 7
Strand: 1
Band: q22.1
Gene start: 100875111
Gene end: 100888664
  
Corresponding Affymetrix probe sets: 201679_at (Human Genome U133 Plus 2.0 Array)   201680_x_at (Human Genome U133 Plus 2.0 Array)   214127_s_at (Human Genome U133 Plus 2.0 Array)   222046_at (Human Genome U133 Plus 2.0 Array)   222047_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000480421
Ensembl peptide - ENSP00000478341
Ensembl peptide - ENSP00000481173
Ensembl peptide - ENSP00000492916
Ensembl peptide - ENSP00000483556
Ensembl peptide - ENSP00000483348
Ensembl peptide - ENSP00000396807
Ensembl peptide - ENSP00000398618
Ensembl peptide - ENSP00000400703
Ensembl peptide - ENSP00000400912
Ensembl peptide - ENSP00000410588
NCBI entrez gene - 51593     See in Manteia.
OMIM - 614469
RefSeq - XM_017012291
RefSeq - NM_001128852
RefSeq - NM_001128853
RefSeq - NM_001128854
RefSeq - NM_015908
RefSeq - XM_005250405
RefSeq - XM_005250406
RefSeq - XM_005250407
RefSeq - XM_005250408
RefSeq - XM_017012290
RefSeq Peptide - NP_001122325
RefSeq Peptide - NP_001122326
RefSeq Peptide - NP_056992
RefSeq Peptide - NP_001122324
swissprot - H7C0U8
swissprot - H7C1K0
swissprot - H7C3A1
swissprot - A0A087X0F4
swissprot - Q9BXP5
swissprot - C9JUL9
swissprot - A0A286YEP7
swissprot - A0A0A0MSP6
Ensembl - ENSG00000087087
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 srrtENSDARG00000017762Danio rerio
 SrrtENSMUSG00000037364Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR007042  Arsenite-resistance protein 2
 IPR021933  Protein of unknown function DUF3546
 IPR035979  RNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000398 mRNA splicing, via spliceosome TAS
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated ISS
 biological_processGO:0008283 cell proliferation IEA
 biological_processGO:0031047 gene silencing by RNA IEA
 biological_processGO:0031053 primary miRNA processing IEA
 biological_processGO:0042795 snRNA transcription by RNA polymerase II TAS
 biological_processGO:0046685 response to arsenic-containing substance NAS
 biological_processGO:0050769 positive regulation of neurogenesis IEA
 biological_processGO:0097150 neuronal stem cell population maintenance IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005737 cytoplasm ISS
 cellular_componentGO:0032991 protein-containing complex IDA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003723 RNA binding HDA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
RNA polymerase II transcribes snRNA genes
mRNA Splicing - Major Pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000136937 NCBP1 / Q09161 / nuclear cap binding protein subunit 1  / complex / reaction
 ENSG00000164902 PHAX / Q9H814 / phosphorylated adaptor for RNA export  / complex / reaction
 ENSG00000114503 NCBP2 / P52298 / nuclear cap binding protein subunit 2  / reaction / complex






 

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