ENSMUSG00000037364


Mus musculus

Features
Gene ID: ENSMUSG00000037364
  
Biological name :Srrt
  
Synonyms : Q99MR6 / Serrate RNA effector molecule homolog / Srrt
  
Possible biological names infered from orthology : Q9BXP5 / serrate, RNA effector molecule
  
Species: Mus musculus
  
Chr. number: 5
Strand: -1
Band: G2
Gene start: 137295704
Gene end: 137307674
  
Corresponding Affymetrix probe sets: 10534694 (MoGene1.0st)   1417655_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000142351
Ensembl peptide - ENSMUSP00000152514
Ensembl peptide - ENSMUSP00000143454
Ensembl peptide - ENSMUSP00000143442
Ensembl peptide - ENSMUSP00000143232
Ensembl peptide - ENSMUSP00000142660
Ensembl peptide - ENSMUSP00000142564
Ensembl peptide - ENSMUSP00000142435
Ensembl peptide - ENSMUSP00000043123
Ensembl peptide - ENSMUSP00000142344
NCBI entrez gene - 83701     See in Manteia.
MGI - MGI:1933527
RefSeq - XM_006504632
RefSeq - NM_001109909
RefSeq - NM_001109910
RefSeq - NM_031405
RefSeq - XM_006504629
RefSeq - XM_006504630
RefSeq - XM_006504631
RefSeq Peptide - NP_001103380
RefSeq Peptide - NP_001103379
RefSeq Peptide - NP_113582
swissprot - A0A0G2JG65
swissprot - A0A0G2JE73
swissprot - A0A0G2JDN3
swissprot - A0A0G2JDF8
swissprot - A0A0G2JDF1
swissprot - A0A0G2JG75
swissprot - Q99MR6
swissprot - A0A1Y7VNN4
Ensembl - ENSMUSG00000037364
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 srrtENSDARG00000017762Danio rerio
 SRRTENSG00000087087Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR007042  Arsenite-resistance protein 2
 IPR021933  Protein of unknown function DUF3546
 IPR035979  RNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0008283 cell proliferation IMP
 biological_processGO:0031047 gene silencing by RNA IEA
 biological_processGO:0031053 primary miRNA processing IEA
 biological_processGO:0050769 positive regulation of neurogenesis IMP
 biological_processGO:0097150 neuronal stem cell population maintenance IMP
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0032991 protein-containing complex IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003677 DNA binding IDA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
RNA polymerase II transcribes snRNA genes
mRNA Splicing - Major Pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000333 decreased bone marrow cell number "decreased number of cells that make up the core cavities of bones when compared to the norm" [tc:Teresa Chu , Mouse Genome Informatics Curator, J:60896]
Show

Allelic Composition: Th/t13
Genetic Background: Not Specified

 MP:0001730 embryonic growth arrest "the cessation of development beyond a particular stage" [J:17509]
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Allelic Composition: Iqgap1tm1Aber/Iqgap1tm1Aber,Iqgap2tm1Vs/Iqgap2tm1Vs
Genetic Background: involves: 129S4/SvJae

 MP:0003694 failure to hatch from the zona pellucida "the embryo fails to break out of the thick solid transparent outer membrane that surrounds the developing ovum and embryo prior to implantation, may be seen in vivo or in cultured embryos" [smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Iqgap1tm1Aber/Iqgap1tm1Aber,Iqgap2tm1Vs/Iqgap2tm1Vs
Genetic Background: involves: 129S4/SvJae

 MP:0003763 abnormal thymus physiology "anomalous function of the primary lymphoid organ that is required for immune system development" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Th/t13
Genetic Background: Not Specified

 MP:0009322 increased splenocyte apoptosis "increase in the number of spleen cells undergoing programmed cell death" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Th/t13
Genetic Background: Not Specified

 MP:0011096 complete embryonic lethality before somite formation "death of all organisms of a given genotype in a population between the point of implantation and somite formation (Mus: E4.5 to less than E8)" [MGI:csmith]
Show

Allelic Composition: Iqgap1tm1Aber/Iqgap1tm1Aber,Iqgap2tm1Vs/Iqgap2tm1Vs
Genetic Background: involves: 129S4/SvJae

 MP:0013504 increased embryonic tissue cell apoptosis "increase in the timing or the number of cells in embryonic tissue undergoing programmed cell death" [MGI:csmith]
Show

Allelic Composition: Iqgap1tm1Aber/Iqgap1tm1Aber,Iqgap2tm1Vs/Iqgap2tm1Vs
Genetic Background: involves: 129S4/SvJae

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000008301 Phax / Q9JJT9 / phosphorylated adaptor for RNA export / Q9H814*  / reaction / complex
 ENSMUSG00000028330 Ncbp1 / Q3UYV9 / Nuclear cap-binding protein subunit 1 / Q09161*  / reaction / complex
 ENSMUSG00000022774 Ncbp2 / Q9CQ49 / Nuclear cap-binding protein subunit 2 / P52298*  / reaction / complex






 

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