ENSG00000091073


Homo sapiens

Features
Gene ID: ENSG00000091073
  
Biological name :DTX2
  
Synonyms : deltex E3 ubiquitin ligase 2 / DTX2 / Q86UW9
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 7
Strand: 1
Band: q11.23
Gene start: 76461676
Gene end: 76505995
  
Corresponding Affymetrix probe sets: 215732_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000390881
Ensembl peptide - ENSP00000415838
Ensembl peptide - ENSP00000411986
Ensembl peptide - ENSP00000410892
Ensembl peptide - ENSP00000409040
Ensembl peptide - ENSP00000407398
Ensembl peptide - ENSP00000403342
Ensembl peptide - ENSP00000399639
Ensembl peptide - ENSP00000397648
Ensembl peptide - ENSP00000392545
Ensembl peptide - ENSP00000392114
Ensembl peptide - ENSP00000322885
Ensembl peptide - ENSP00000387894
Ensembl peptide - ENSP00000389231
Ensembl peptide - ENSP00000390218
NCBI entrez gene - 113878     See in Manteia.
OMIM - 613141
RefSeq - XM_017011726
RefSeq - XM_005250132
RefSeq - XM_005250131
RefSeq - XM_017011725
RefSeq - XM_017011724
RefSeq - XM_017011723
RefSeq - XM_011515775
RefSeq - XM_011515774
RefSeq - XM_011515773
RefSeq - NM_001102594
RefSeq - NM_001102595
RefSeq - NM_001102596
RefSeq - NM_020892
RefSeq - XM_017011728
RefSeq - XM_017011727
RefSeq - XM_011515772
RefSeq Peptide - NP_001096065
RefSeq Peptide - NP_001096064
RefSeq Peptide - NP_001096066
RefSeq Peptide - NP_065943
swissprot - Q86UW9
swissprot - E7ET89
swissprot - H7C3B8
swissprot - C9IYX1
swissprot - C9JEH4
swissprot - C9JF39
swissprot - C9JII1
swissprot - C9JLU8
swissprot - C9JS11
swissprot - C9JVC8
swissprot - C9JY61
Ensembl - ENSG00000091073
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dtx2ENSDARG00000032933Danio rerio
 DTX2ENSGALG00000001905Gallus gallus
 Dtx2ENSMUSG00000004947Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
DTX1 / Q86Y01 / deltex E3 ubiquitin ligase 1ENSG0000013514447
DTX4 / Q9Y2E6 / deltex E3 ubiquitin ligase 4ENSG0000011004245
DTX3L / Q8TDB6 / deltex E3 ubiquitin ligase 3LENSG0000016384023
DTX3 / Q8N9I9 / deltex E3 ubiquitin ligase 3ENSG0000017849816


Protein motifs (from Interpro)
Interpro ID Name
 IPR001841  Zinc finger, RING-type
 IPR004170  WWE domain
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR018123  WWE domain, subgroup
 IPR018957  Zinc finger, C3HC4 RING-type
 IPR037197  WWE domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007219 Notch signaling pathway IEA
 biological_processGO:0016567 protein ubiquitination IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0031965 nuclear membrane IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Activated NOTCH1 Transmits Signal to the Nucleus


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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