ENSG00000092098


Homo sapiens

Features
Gene ID: ENSG00000092098
  
Biological name :RNF31
  
Synonyms : Q96EP0 / ring finger protein 31 / RNF31
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 14
Strand: 1
Band: q12
Gene start: 24146683
Gene end: 24160661
  
Corresponding Affymetrix probe sets: 220788_s_at (Human Genome U133 Plus 2.0 Array)   225122_at (Human Genome U133 Plus 2.0 Array)   231635_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000453423
Ensembl peptide - ENSP00000453471
Ensembl peptide - ENSP00000453501
Ensembl peptide - ENSP00000453574
Ensembl peptide - ENSP00000453595
Ensembl peptide - ENSP00000453601
Ensembl peptide - ENSP00000453645
Ensembl peptide - ENSP00000453672
Ensembl peptide - ENSP00000453948
Ensembl peptide - ENSP00000454032
Ensembl peptide - ENSP00000454048
Ensembl peptide - ENSP00000454140
Ensembl peptide - ENSP00000315112
Ensembl peptide - ENSP00000452820
Ensembl peptide - ENSP00000452972
NCBI entrez gene - 55072     See in Manteia.
OMIM - 612487
RefSeq - NM_001310332
RefSeq - NM_017999
RefSeq Peptide - NP_001297261
RefSeq Peptide - NP_060469
swissprot - Q96EP0
swissprot - H0YKI4
swissprot - H0YKX0
swissprot - H0YM13
swissprot - H0YM57
swissprot - H0YM83
swissprot - H0YMG4
swissprot - H0YMG8
swissprot - H0YMK6
swissprot - H0YMN0
swissprot - H0YNC1
swissprot - H0YNJ0
swissprot - H0YNK5
swissprot - H0YNT1
Ensembl - ENSG00000092098
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 FO834800.1ENSDARG00000090770Danio rerio
 FO834800.2ENSDARG00000113057Danio rerio
 Rnf31ENSMUSG00000047098Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
AL136295.5ENSG0000025952951


Protein motifs (from Interpro)
Interpro ID Name
 IPR001876  Zinc finger, RanBP2-type
 IPR002867  IBR domain
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR015940  Ubiquitin-associated domain
 IPR017907  Zinc finger, RING-type, conserved site
 IPR018997  PUB domain
 IPR026254  E3 ubiquitin-protein ligase RNF31
 IPR032065  E3 ubiquitin-protein ligase RNF31, UBA-like domain
 IPR036339  PUB-like domain superfamily
 IPR036443  Zinc finger, RanBP2-type superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000209 protein polyubiquitination IDA
 biological_processGO:0007249 I-kappaB kinase/NF-kappaB signaling TAS
 biological_processGO:0010803 regulation of tumor necrosis factor-mediated signaling pathway TAS
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0023035 CD40 signaling pathway ISS
 biological_processGO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling IDA
 biological_processGO:0050852 T cell receptor signaling pathway IDA
 biological_processGO:0051092 positive regulation of NF-kappaB transcription factor activity IDA
 biological_processGO:0097039 protein linear polyubiquitination IDA
 biological_processGO:1903955 positive regulation of protein targeting to mitochondrion IMP
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0009898 cytoplasmic side of plasma membrane ISS
 cellular_componentGO:0035631 CD40 receptor complex ISS
 cellular_componentGO:0071797 LUBAC complex IEA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0031625 ubiquitin protein ligase binding IPI
 molecular_functionGO:0043130 ubiquitin binding IDA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Regulation of TNFR1 signaling
TNFR1-induced NFkappaB signaling pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000269335 IKBKG / Q9Y6K9 / inhibitor of nuclear factor kappa B kinase subunit gamma  / complex / reaction
 ENSG00000213341 CHUK / O15111 / conserved helix-loop-helix ubiquitous kinase  / reaction / complex
 ENSG00000125826 RBCK1 / Q9BYM8 / RANBP2-type and C3HC4-type zinc finger containing 1  / complex
 ENSG00000104365 IKBKB / O14920 / inhibitor of nuclear factor kappa B kinase subunit beta  / complex / reaction
 ENSG00000154124 OTULIN / Q96BN8 / OTU deubiquitinase with linear linkage specificity  / complex / reaction
 ENSG00000179526 Q9H0F6 / SHARPIN / SHANK associated RH domain interactor  / complex






 

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