ENSG00000096401


Homo sapiens

Features
Gene ID: ENSG00000096401
  
Biological name :CDC5L
  
Synonyms : CDC5L / cell division cycle 5 like / Q99459
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 6
Strand: 1
Band: p21.1
Gene start: 44387525
Gene end: 44450426
  
Corresponding Affymetrix probe sets: 209055_s_at (Human Genome U133 Plus 2.0 Array)   209056_s_at (Human Genome U133 Plus 2.0 Array)   209057_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000360532
NCBI entrez gene - 988     See in Manteia.
OMIM - 602868
RefSeq - NM_001253
RefSeq Peptide - NP_001244
swissprot - Q99459
Ensembl - ENSG00000096401
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cdc5lENSDARG00000043797Danio rerio
 CDC5LENSGALG00000016704Gallus gallus
 Cdc5lENSMUSG00000023932Mus musculus
 Gm32717ENSMUSG00000112216Mus musculus
 Gm32802ENSMUSG00000112252Mus musculus
 Gm9040ENSMUSG00000112814Mus musculus
 Gm9044ENSMUSG00000112419Mus musculus
 Gm9045ENSMUSG00000112027Mus musculus
 Gm9046ENSMUSG00000112781Mus musculus
 Gm9048ENSMUSG00000112495Mus musculus
 Gm9049ENSMUSG00000112919Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001005  SANT/Myb domain
 IPR009057  Homeobox-like domain superfamily
 IPR017930  Myb domain
 IPR021786  Pre-mRNA splicing factor component Cdc5p/Cef1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000278 mitotic cell cycle IEA
 biological_processGO:0000398 mRNA splicing, via spliceosome TAS
 biological_processGO:0006281 DNA repair IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IBA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0006397 mRNA processing IEA
 biological_processGO:0006974 cellular response to DNA damage stimulus IEA
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0008380 RNA splicing IEA
 biological_processGO:0030154 cell differentiation IBA
 biological_processGO:0044344 cellular response to fibroblast growth factor stimulus IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IDA
 biological_processGO:0071352 cellular response to interleukin-2 IEA
 biological_processGO:0072422 signal transduction involved in DNA damage checkpoint IMP
 biological_processGO:1904568 cellular response to wortmannin IEA
 biological_processGO:1990090 cellular response to nerve growth factor stimulus IEA
 biological_processGO:1990646 cellular response to prolactin IEA
 cellular_componentGO:0000974 Prp19 complex IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005662 DNA replication factor A complex IDA
 cellular_componentGO:0005681 spliceosomal complex IEA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0016020 membrane HDA
 cellular_componentGO:0016607 nuclear speck IDA
 cellular_componentGO:0032993 protein-DNA complex IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 cellular_componentGO:0071007 U2-type catalytic step 2 spliceosome IDA
 cellular_componentGO:0071013 catalytic step 2 spliceosome IDA
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IDA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding IBA
 molecular_functionGO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting IBA
 molecular_functionGO:0001222 transcription corepressor binding IEA
 molecular_functionGO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding IDA
 molecular_functionGO:0003677 DNA binding NAS
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008157 protein phosphatase 1 binding IEA
 molecular_functionGO:0019901 protein kinase binding IEA
 molecular_functionGO:0043522 leucine zipper domain binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IBA
 molecular_functionGO:0044212 transcription regulatory region DNA binding IBA
 molecular_functionGO:0071987 WD40-repeat domain binding IDA


Pathways (from Reactome)
Pathway description
mRNA Splicing - Major Pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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