ENSMUSG00000023932


Mus musculus

Features
Gene ID: ENSMUSG00000023932
  
Biological name :Cdc5l
  
Synonyms : Cdc5l / Cell division cycle 5-like protein / Q6A068
  
Possible biological names infered from orthology : cell division cycle 5 like / Q99459
  
Species: Mus musculus
  
Chr. number: 17
Strand: -1
Band: B3
Gene start: 45391892
Gene end: 45433707
  
Corresponding Affymetrix probe sets: 10366579 (MoGene1.0st)   10366581 (MoGene1.0st)   10372726 (MoGene1.0st)   10372728 (MoGene1.0st)   10372733 (MoGene1.0st)   10372735 (MoGene1.0st)   10372737 (MoGene1.0st)   10372739 (MoGene1.0st)   10372741 (MoGene1.0st)   10372743 (MoGene1.0st)   10451083 (MoGene1.0st)   1428092_at (Mouse Genome 430 2.0 Array)   1460429_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000024727
NCBI entrez gene - 71702     See in Manteia.
MGI - MGI:1918952
RefSeq - NM_152810
RefSeq Peptide - NP_690023
swissprot - Q3UCF2
swissprot - Q6A068
Ensembl - ENSMUSG00000023932
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cdc5lENSDARG00000043797Danio rerio
 CDC5LENSGALG00000016704Gallus gallus
 CDC5LENSG00000096401Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Gm9045 / predicted gene 9045 / CDC5L* / Q99459* / cell division cycle 5 like*ENSMUSG0000011202798
Gm9049 / predicted gene 9049 / CDC5L* / Q99459* / cell division cycle 5 like*ENSMUSG0000011291998
Gm9046 / CDC5L* / Q99459* / cell division cycle 5 like*ENSMUSG0000011278198
Gm9040 / predicted gene 9040 / CDC5L* / Q99459* / cell division cycle 5 like*ENSMUSG0000011281498
Gm32802 / predicted gene, 32802 / CDC5L* / Q99459* / cell division cycle 5 like*ENSMUSG0000011225298
Gm9044 / predicted gene 9044 / CDC5L* / Q99459* / cell division cycle 5 like*ENSMUSG0000011241998
Gm9048 / CDC5L* / Q99459* / cell division cycle 5 like*ENSMUSG0000011249598
Gm32717 / predicted gene, 32717 / CDC5L* / Q99459* / cell division cycle 5 like*ENSMUSG0000011221698


Protein motifs (from Interpro)
Interpro ID Name
 IPR001005  SANT/Myb domain
 IPR009057  Homeobox-like domain superfamily
 IPR017930  Myb domain
 IPR021786  Pre-mRNA splicing factor component Cdc5p/Cef1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000398 mRNA splicing, via spliceosome ISS
 biological_processGO:0006281 DNA repair IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IBA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0006397 mRNA processing IEA
 biological_processGO:0006974 cellular response to DNA damage stimulus IEA
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0008380 RNA splicing IEA
 biological_processGO:0030154 cell differentiation IBA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II ISO
 biological_processGO:0072422 signal transduction involved in DNA damage checkpoint ISO
 cellular_componentGO:0000974 Prp19 complex ISO
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005654 nucleoplasm ISO
 cellular_componentGO:0005662 DNA replication factor A complex ISO
 cellular_componentGO:0005681 spliceosomal complex IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0016607 nuclear speck ISO
 cellular_componentGO:0071013 catalytic step 2 spliceosome ISO
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding ISO
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding IBA
 molecular_functionGO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting IBA
 molecular_functionGO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding ISO
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IBA
 molecular_functionGO:0044212 transcription regulatory region DNA binding IBA
 molecular_functionGO:0071987 WD40-repeat domain binding ISS


Pathways (from Reactome)
Pathway description
mRNA Splicing - Major Pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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