ENSG00000099860


Homo sapiens

Features
Gene ID: ENSG00000099860
  
Biological name :GADD45B
  
Synonyms : GADD45B / growth arrest and DNA damage inducible beta / O75293
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: 1
Band: p13.3
Gene start: 2476122
Gene end: 2478259
  
Corresponding Affymetrix probe sets: 207574_s_at (Human Genome U133 Plus 2.0 Array)   209304_x_at (Human Genome U133 Plus 2.0 Array)   209305_s_at (Human Genome U133 Plus 2.0 Array)   213560_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000466414
Ensembl peptide - ENSP00000468374
Ensembl peptide - ENSP00000468620
Ensembl peptide - ENSP00000215631
Ensembl peptide - ENSP00000467490
NCBI entrez gene - 4616     See in Manteia.
OMIM - 604948
RefSeq - XM_017026822
RefSeq - NM_015675
RefSeq Peptide - NP_056490
swissprot - K7EM97
swissprot - O75293
swissprot - Q6IX74
swissprot - K7EPQ8
Ensembl - ENSG00000099860
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gadd45baENSDARG00000027744Danio rerio
 gadd45bbENSDARG00000013576Danio rerio
 GADD45BENSGALG00000029968Gallus gallus
 P22339ENSMUSG00000015312Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P24522 / GADD45A / growth arrest and DNA damage inducible alphaENSG0000011671757
O95257 / GADD45G / growth arrest and DNA damage inducible gammaENSG0000013022254


Protein motifs (from Interpro)
Interpro ID Name
 IPR004038  Ribosomal protein L7Ae/L30e/S12e/Gadd45
 IPR024824  Growth arrest and DNA damage-inducible protein GADD45
 IPR029064  50S ribosomal protein L30e-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000185 activation of MAPKKK activity IDA
 biological_processGO:0000186 activation of MAPKK activity IEA
 biological_processGO:0006469 negative regulation of protein kinase activity IEA
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0006950 response to stress IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0043065 positive regulation of apoptotic process IDA
 biological_processGO:0046330 positive regulation of JNK cascade IDA
 biological_processGO:0051726 regulation of cell cycle IEA
 biological_processGO:1900745 positive regulation of p38MAPK cascade IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IDA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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