ENSG00000100034


Homo sapiens

Features
Gene ID: ENSG00000100034
  
Biological name :PPM1F
  
Synonyms : P49593 / PPM1F / protein phosphatase, Mg2+/Mn2+ dependent 1F
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 22
Strand: -1
Band: q11.22
Gene start: 21919420
Gene end: 21952837
  
Corresponding Affymetrix probe sets: 1555091_at (Human Genome U133 Plus 2.0 Array)   1555470_a_at (Human Genome U133 Plus 2.0 Array)   203063_at (Human Genome U133 Plus 2.0 Array)   37384_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000263212
Ensembl peptide - ENSP00000392372
Ensembl peptide - ENSP00000388350
Ensembl peptide - ENSP00000384930
Ensembl peptide - ENSP00000380632
NCBI entrez gene - 9647     See in Manteia.
RefSeq - XM_011530556
RefSeq - NM_014634
RefSeq Peptide - NP_055449
swissprot - B5MCT7
swissprot - A8MX49
swissprot - C9JL74
swissprot - P49593
swissprot - C9J2F3
Ensembl - ENSG00000100034
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ppm1fENSDARG00000005786Danio rerio
 PPM1FENSGALG00000039121Gallus gallus
 Ppm1fENSMUSG00000026181Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PPM1E / Q8WY54 / protein phosphatase, Mg2+/Mn2+ dependent 1EENSG0000017517547
ILKAP / Q9H0C8 / ILK associated serine/threonine phosphataseENSG0000013232325
PPM1K / Q8N3J5 / protein phosphatase, Mg2+/Mn2+ dependent 1KENSG0000016364423
PPM1L / Q5SGD2 / protein phosphatase, Mg2+/Mn2+ dependent 1LENSG0000016359020


Protein motifs (from Interpro)
Interpro ID Name
 IPR000222  PPM-type phosphatase, divalent cation binding
 IPR001932  PPM-type phosphatase domain
 IPR015655  Protein phosphatase 2C family
 IPR036457  PPM-type phosphatase domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006469 negative regulation of protein kinase activity IDA
 biological_processGO:0006470 protein dephosphorylation IEA
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0010628 positive regulation of gene expression IMP
 biological_processGO:0010634 positive regulation of epithelial cell migration IMP
 biological_processGO:0010811 positive regulation of cell-substrate adhesion IMP
 biological_processGO:0016576 histone dephosphorylation IEA
 biological_processGO:0033137 negative regulation of peptidyl-serine phosphorylation IDA
 biological_processGO:0035690 cellular response to drug IDA
 biological_processGO:0035970 peptidyl-threonine dephosphorylation IDA
 biological_processGO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process IEA
 biological_processGO:0044387 negative regulation of protein kinase activity by regulation of protein phosphorylation IDA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IMP
 biological_processGO:0045927 positive regulation of growth IMP
 biological_processGO:0050921 positive regulation of chemotaxis IMP
 biological_processGO:0051496 positive regulation of stress fiber assembly IMP
 biological_processGO:0051894 positive regulation of focal adhesion assembly IMP
 biological_processGO:0097193 intrinsic apoptotic signaling pathway IDA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0032991 protein-containing complex IDA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004721 phosphoprotein phosphatase activity IEA
 molecular_functionGO:0004722 protein serine/threonine phosphatase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0033192 calmodulin-dependent protein phosphatase activity IDA
 molecular_functionGO:0043169 cation binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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