ENSMUSG00000026181


Mus musculus

Features
Gene ID: ENSMUSG00000026181
  
Biological name :Ppm1f
  
Synonyms : Ppm1f / Protein phosphatase 1F / Q8CGA0
  
Possible biological names infered from orthology : P49593 / protein phosphatase, Mg2+/Mn2+ dependent 1F
  
Species: Mus musculus
  
Chr. number: 16
Strand: 1
Band: A3
Gene start: 16896469
Gene end: 16927375
  
Corresponding Affymetrix probe sets: 10433929 (MoGene1.0st)   1430631_at (Mouse Genome 430 2.0 Array)   1454934_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000027373
NCBI entrez gene - 68606     See in Manteia.
MGI - MGI:1918464
RefSeq - XM_017317124
RefSeq - NM_176833
RefSeq - XM_006522508
RefSeq Peptide - NP_789803
swissprot - Q8CGA0
Ensembl - ENSMUSG00000026181
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ppm1fENSDARG00000005786Danio rerio
 PPM1FENSGALG00000039121Gallus gallus
 PPM1FENSG00000100034Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Ppm1e / Q80TL0 / Protein phosphatase 1E / Q8WY54* / protein phosphatase, Mg2+/Mn2+ dependent 1E*ENSMUSG0000004644248
Ilkap / Q8R0F6 / Mus musculus integrin-linked kinase-associated serine/threonine phosphatase 2C (Ilkap), transcript variant 2, mRNA. / Q9H0C8* / ILK associated serine/threonine phosphatase*ENSMUSG0000002630924
Ppm1k / Q8BXN7 / protein phosphatase 1K (PP2C domain containing) / Q8N3J5* / protein phosphatase, Mg2+/Mn2+ dependent 1K*ENSMUSG0000003782623
Ppm1l / Q8BHN0 / Protein phosphatase 1L / Q5SGD2* / protein phosphatase, Mg2+/Mn2+ dependent 1L*ENSMUSG0000002778420


Protein motifs (from Interpro)
Interpro ID Name
 IPR000222  PPM-type phosphatase, divalent cation binding
 IPR001932  PPM-type phosphatase domain
 IPR015655  Protein phosphatase 2C family
 IPR036457  PPM-type phosphatase domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006469 negative regulation of protein kinase activity IEA
 biological_processGO:0006470 protein dephosphorylation IEA
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0010628 positive regulation of gene expression IEA
 biological_processGO:0010634 positive regulation of epithelial cell migration IEA
 biological_processGO:0010811 positive regulation of cell-substrate adhesion IEA
 biological_processGO:0016576 histone dephosphorylation IEA
 biological_processGO:0033137 negative regulation of peptidyl-serine phosphorylation IEA
 biological_processGO:0035690 cellular response to drug IEA
 biological_processGO:0035970 peptidyl-threonine dephosphorylation IEA
 biological_processGO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process IEA
 biological_processGO:0044387 negative regulation of protein kinase activity by regulation of protein phosphorylation IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IEA
 biological_processGO:0045927 positive regulation of growth IEA
 biological_processGO:0050921 positive regulation of chemotaxis IEA
 biological_processGO:0051496 positive regulation of stress fiber assembly IEA
 biological_processGO:0051894 positive regulation of focal adhesion assembly IEA
 biological_processGO:0097193 intrinsic apoptotic signaling pathway IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0032991 protein-containing complex IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004721 phosphoprotein phosphatase activity IEA
 molecular_functionGO:0004722 protein serine/threonine phosphatase activity ISO
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0033192 calmodulin-dependent protein phosphatase activity IEA
 molecular_functionGO:0043169 cation binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001399 hyperactivity "general restlessness or excessive movement; more frequent movement from one place to another" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409, J:57125]
Show

Allelic Composition: Cfmq3129X1/SvJ/Cfmq3C57BL/6J,Cftrtm1Unc/Cftrtm1Unc
Genetic Background: involves: 129X1/SvJ * C57BL/6J

 MP:0001973 increased thermal nociceptive threshold "a greater than average point at which thermal pain sensation is first detectable" [What s Wrong With My Mouse?:ISBN 0-471-31639-3, J:17194]
Show

Allelic Composition: Cfmq3129X1/SvJ/Cfmq3C57BL/6J,Cftrtm1Unc/Cftrtm1Unc
Genetic Background: involves: 129X1/SvJ * C57BL/6J

 MP:0011100 complete preweaning lethality "death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
Show

Allelic Composition: Cfmq3129X1/SvJ/Cfmq3C57BL/6J,Cftrtm1Unc/Cftrtm1Unc
Genetic Background: involves: 129X1/SvJ * C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr