ENSMUSG00000026309


Mus musculus

Features
Gene ID: ENSMUSG00000026309
  
Biological name :Ilkap
  
Synonyms : Ilkap / Mus musculus integrin-linked kinase-associated serine/threonine phosphatase 2C (Ilkap), transcript variant 2, mRNA. / Q8R0F6
  
Possible biological names infered from orthology : ILK associated serine/threonine phosphatase / Q9H0C8
  
Species: Mus musculus
  
Chr. number: 1
Strand: -1
Band: D
Gene start: 91373861
Gene end: 91398815
  
Corresponding Affymetrix probe sets: 10356577 (MoGene1.0st)   1452506_a_at (Mouse Genome 430 2.0 Array)   1453784_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000139834
Ensembl peptide - ENSMUSP00000027534
Ensembl peptide - ENSMUSP00000139962
Ensembl peptide - ENSMUSP00000140905
Ensembl peptide - ENSMUSP00000140752
Ensembl peptide - ENSMUSP00000140182
Ensembl peptide - ENSMUSP00000140074
Ensembl peptide - ENSMUSP00000140048
NCBI entrez gene - 67444     See in Manteia.
MGI - MGI:1914694
RefSeq - XM_017322168
RefSeq - XM_006529808
RefSeq - XM_006529809
RefSeq - XM_006529810
RefSeq - XM_006529811
RefSeq - XM_006529812
RefSeq - XM_006529813
RefSeq - XM_006529814
RefSeq - XM_006529815
RefSeq - XM_006529816
RefSeq - XM_011248065
RefSeq - NM_001355152
RefSeq - NM_023343
RefSeq - XM_006529807
RefSeq Peptide - NP_001342081
RefSeq Peptide - NP_075832
swissprot - A0A087WQG1
swissprot - A0A087WQ78
swissprot - A0A087WQ55
swissprot - A0A087WS54
swissprot - Q8R0F6
swissprot - A0A087WPM3
swissprot - A0A087WPY0
swissprot - A0A087WRS5
Ensembl - ENSMUSG00000026309
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ilkapENSDARG00000040615Danio rerio
 ILKAPENSGALG00000006253Gallus gallus
 ILKAPENSG00000132323Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Ppm1f / Q8CGA0 / Protein phosphatase 1F / P49593* / protein phosphatase, Mg2+/Mn2+ dependent 1F*ENSMUSG0000002618128
Ppm1e / Q80TL0 / Protein phosphatase 1E / Q8WY54* / protein phosphatase, Mg2+/Mn2+ dependent 1E*ENSMUSG0000004644227
Ppm1l / Q8BHN0 / Protein phosphatase 1L / Q5SGD2* / protein phosphatase, Mg2+/Mn2+ dependent 1L*ENSMUSG0000002778424
Ppm1k / Q8BXN7 / protein phosphatase 1K (PP2C domain containing) / Q8N3J5* / protein phosphatase, Mg2+/Mn2+ dependent 1K*ENSMUSG0000003782622


Protein motifs (from Interpro)
Interpro ID Name
 IPR000222  PPM-type phosphatase, divalent cation binding
 IPR001932  PPM-type phosphatase domain
 IPR015655  Protein phosphatase 2C family
 IPR036457  PPM-type phosphatase domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006470 protein dephosphorylation IEA
 biological_processGO:0007229 integrin-mediated signaling pathway IEA
 biological_processGO:0016310 phosphorylation IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004721 phosphoprotein phosphatase activity IEA
 molecular_functionGO:0004722 protein serine/threonine phosphatase activity IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0043169 cation binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0003858 enhanced coordination "improved ability to execute integrated movements of muscle" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Prnptm1Cwe/Prnptm1Cwe,Sprntm1Geno/Sprntm1Geno
Genetic Background: involves: 129S2/SvPas * 129S7/SvEvBrd * C57BL/6J * FVB/N

 MP:0003982 increased cholesterol level "greater than normal concentration in the body of these most abundant steroids in animal tissues, and precursors to steroid hormones and bile salts; also components of plasma membranes" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Prnptm1Cwe/Prnptm1Cwe,Sprntm1Geno/Sprntm1Geno
Genetic Background: involves: 129S2/SvPas * 129S7/SvEvBrd * C57BL/6J * FVB/N

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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