ENSG00000100060


Homo sapiens

Features
Gene ID: ENSG00000100060
  
Biological name :MFNG
  
Synonyms : MFNG / MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase / O00587
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 22
Strand: -1
Band: q13.1
Gene start: 37469063
Gene end: 37486401
  
Corresponding Affymetrix probe sets: 204152_s_at (Human Genome U133 Plus 2.0 Array)   204153_s_at (Human Genome U133 Plus 2.0 Array)   213783_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000407094
Ensembl peptide - ENSP00000414342
Ensembl peptide - ENSP00000414222
Ensembl peptide - ENSP00000413855
Ensembl peptide - ENSP00000407110
Ensembl peptide - ENSP00000349490
Ensembl peptide - ENSP00000389274
Ensembl peptide - ENSP00000394081
NCBI entrez gene - 4242     See in Manteia.
OMIM - 602577
RefSeq - NM_001166343
RefSeq - NM_002405
RefSeq Peptide - NP_001159815
RefSeq Peptide - NP_002396
swissprot - H0Y6Q9
swissprot - A9UJQ1
swissprot - O00587
swissprot - A9UJP9
swissprot - A0A1B0GX02
swissprot - F8WE05
swissprot - F8WE21
Ensembl - ENSG00000100060
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mfngENSDARG00000042925Danio rerio
 MFNGENSGALG00000012442Gallus gallus
 MfngENSMUSG00000018169Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
LFNG / Q8NES3 / LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferaseENSG0000010600358
RFNG / Q9Y644 / RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferaseENSG0000016973352


Protein motifs (from Interpro)
Interpro ID Name
 IPR003378  Fringe-like
 IPR017374  Fringe
 IPR029044  Nucleotide-diphospho-sugar transferases


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002315 marginal zone B cell differentiation ISS
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007389 pattern specification process TAS
 biological_processGO:0008593 regulation of Notch signaling pathway ISS
 biological_processGO:0032092 positive regulation of protein binding IEA
 biological_processGO:0036066 protein O-linked fucosylation ISS
 biological_processGO:0045747 positive regulation of Notch signaling pathway IEA
 cellular_componentGO:0000139 Golgi membrane IEA
 cellular_componentGO:0005615 extracellular space TAS
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030173 integral component of Golgi membrane IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016757 transferase activity, transferring glycosyl groups IEA
 molecular_functionGO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Pre-NOTCH Processing in Golgi


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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