ENSG00000100097


Homo sapiens

Features
Gene ID: ENSG00000100097
  
Biological name :LGALS1
  
Synonyms : galectin 1 / LGALS1 / P09382
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 22
Strand: 1
Band: q13.1
Gene start: 37675608
Gene end: 37679806
  
Corresponding Affymetrix probe sets: 201105_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000388296
Ensembl peptide - ENSP00000404414
Ensembl peptide - ENSP00000215909
NCBI entrez gene - 3956     See in Manteia.
OMIM - 150570
RefSeq - NM_002305
RefSeq Peptide - NP_002296
swissprot - P09382
swissprot - F8WCQ5
swissprot - F8WEI7
Ensembl - ENSG00000100097
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 lgals1l1ENSDARG00000088711Danio rerio
 lgals2aENSDARG00000054942Danio rerio
 lgals2bENSDARG00000038153Danio rerio
 LGALS1ENSGALG00000012420Gallus gallus
 Lgals1ENSMUSG00000068220Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
LGALS2 / P05162 / galectin 2ENSG0000010007941


Protein motifs (from Interpro)
Interpro ID Name
 IPR001079  Galectin, carbohydrate recognition domain
 IPR013320  Concanavalin A-like lectin/glucanase domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002317 plasma cell differentiation IEA
 biological_processGO:0006915 apoptotic process TAS
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0010812 negative regulation of cell-substrate adhesion IEA
 biological_processGO:0010977 negative regulation of neuron projection development IEA
 biological_processGO:0031295 T cell costimulation IEA
 biological_processGO:0034120 positive regulation of erythrocyte aggregation IEA
 biological_processGO:0035900 response to isolation stress IEA
 biological_processGO:0042493 response to drug IEA
 biological_processGO:0042981 regulation of apoptotic process TAS
 biological_processGO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling HMP
 biological_processGO:0043687 post-translational protein modification TAS
 biological_processGO:0044267 cellular protein metabolic process TAS
 biological_processGO:0045445 myoblast differentiation IEA
 biological_processGO:0046598 positive regulation of viral entry into host cell IDA
 biological_processGO:0048678 response to axon injury IEA
 biological_processGO:0071333 cellular response to glucose stimulus IEA
 biological_processGO:0071407 cellular response to organic cyclic compound IEA
 cellular_componentGO:0005576 extracellular region IDA
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0005622 intracellular IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005788 endoplasmic reticulum lumen TAS
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0009986 cell surface IEA
 cellular_componentGO:0031012 extracellular matrix ISS
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0003723 RNA binding HDA
 molecular_functionGO:0004871 obsolete signal transducer activity HMP
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0030246 carbohydrate binding IEA
 molecular_functionGO:0030395 lactose binding IEA
 molecular_functionGO:0042803 protein homodimerization activity IEA
 molecular_functionGO:0043236 laminin binding IEA


Pathways (from Reactome)
Pathway description
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
Post-translational protein phosphorylation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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