ENSG00000100316


Homo sapiens

Features
Gene ID: ENSG00000100316
  
Biological name :RPL3
  
Synonyms : P39023 / ribosomal protein L3 / RPL3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 22
Strand: -1
Band: q13.1
Gene start: 39312882
Gene end: 39320389
  
Corresponding Affymetrix probe sets: 201217_x_at (Human Genome U133 Plus 2.0 Array)   211073_x_at (Human Genome U133 Plus 2.0 Array)   211666_x_at (Human Genome U133 Plus 2.0 Array)   212039_x_at (Human Genome U133 Plus 2.0 Array)   215963_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000385762
Ensembl peptide - ENSP00000412713
Ensembl peptide - ENSP00000415198
Ensembl peptide - ENSP00000416273
Ensembl peptide - ENSP00000346001
Ensembl peptide - ENSP00000386101
NCBI entrez gene - 6122     See in Manteia.
OMIM - 604163
RefSeq - NM_000967
RefSeq - NM_001033853
RefSeq Peptide - NP_000958
RefSeq Peptide - NP_001029025
swissprot - P39023
swissprot - B5MCW2
swissprot - F8WCR1
swissprot - G5E9G0
swissprot - H7C3M2
swissprot - H7C422
Ensembl - ENSG00000100316
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rpl3ENSDARG00000003599Danio rerio
 RPL3ENSGALG00000012172Gallus gallus
 Rpl3ENSMUSG00000060036Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
RPL3L / Q92901 / ribosomal protein L3 likeENSG0000014098677


Protein motifs (from Interpro)
Interpro ID Name
 IPR000597  Ribosomal protein L3
 IPR009000  Translation protein, beta-barrel domain superfamily
 IPR019926  Ribosomal protein L3, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000027 ribosomal large subunit assembly IBA
 biological_processGO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay TAS
 biological_processGO:0006364 rRNA processing TAS
 biological_processGO:0006412 translation IEA
 biological_processGO:0006413 translational initiation TAS
 biological_processGO:0006614 SRP-dependent cotranslational protein targeting to membrane TAS
 biological_processGO:0019083 viral transcription TAS
 biological_processGO:0071353 cellular response to interleukin-4 IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005730 nucleolus IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0005840 ribosome IEA
 cellular_componentGO:0005925 focal adhesion HDA
 cellular_componentGO:0022625 cytosolic large ribosomal subunit IEA
 cellular_componentGO:0032991 protein-containing complex IDA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0003723 RNA binding TAS
 molecular_functionGO:0003735 structural constituent of ribosome IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008097 5S rRNA binding IEA


Pathways (from Reactome)
Pathway description
L13a-mediated translational silencing of Ceruloplasmin expression
Peptide chain elongation
SRP-dependent cotranslational protein targeting to membrane
Viral mRNA Translation
Selenocysteine synthesis
Major pathway of rRNA processing in the nucleolus and cytosol
Formation of a pool of free 40S subunits
GTP hydrolysis and joining of the 60S ribosomal subunit
Eukaryotic Translation Termination
Regulation of expression of SLITs and ROBOs
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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