ENSG00000100979


Homo sapiens

Features
Gene ID: ENSG00000100979
  
Biological name :PLTP
  
Synonyms : P55058 / phospholipid transfer protein / PLTP
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 20
Strand: -1
Band: q13.12
Gene start: 45898621
Gene end: 45912155
  
Corresponding Affymetrix probe sets: 202075_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000361497
Ensembl peptide - ENSP00000411671
Ensembl peptide - ENSP00000417138
Ensembl peptide - ENSP00000335290
Ensembl peptide - ENSP00000361508
NCBI entrez gene - 5360     See in Manteia.
OMIM - 172425
RefSeq - NM_001242921
RefSeq - NM_001242920
RefSeq - NM_006227
RefSeq - NM_182676
RefSeq Peptide - NP_001229849
RefSeq Peptide - NP_001229850
RefSeq Peptide - NP_006218
RefSeq Peptide - NP_872617
swissprot - P55058
Ensembl - ENSG00000100979
  
Related genetic diseases (OMIM): 172425 - [High density lipoprotein cholesterol level QTL 9]
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pltpENSDARG00000104495Danio rerio
 PLTPENSGALG00000036686Gallus gallus
 PltpENSMUSG00000017754Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
LBP / P18428 / lipopolysaccharide binding proteinENSG0000012998824
BPIFC / Q8NFQ6 / BPI fold containing family CENSG0000018445924
BPI / P17213 / bactericidal/permeability-increasing proteinENSG0000010142524


Protein motifs (from Interpro)
Interpro ID Name
 IPR001124  Lipid-binding serum glycoprotein, C-terminal
 IPR017942  Lipid-binding serum glycoprotein, N-terminal
 IPR017943  Bactericidal permeability-increasing protein, alpha/beta domain superfamily
 IPR017954  Lipid-binding serum glycoprotein, conserved site
 IPR030179  Phospholipid transfer protein
 IPR030675  Lipid binding protein BPI/LBP
 IPR032942  BPI/LBP/Plunc family


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006629 lipid metabolic process TAS
 biological_processGO:0006869 lipid transport IDA
 biological_processGO:0010189 vitamin E biosynthetic process IEA
 biological_processGO:0010875 positive regulation of cholesterol efflux IDA
 biological_processGO:0015914 phospholipid transport IDA
 biological_processGO:0030317 flagellated sperm motility IEA
 biological_processGO:0034375 high-density lipoprotein particle remodeling IDA
 biological_processGO:0035627 ceramide transport IDA
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005615 extracellular space HDA
 cellular_componentGO:0034364 high-density lipoprotein particle IDA
 molecular_functionGO:0005319 lipid transporter activity IDA
 molecular_functionGO:0005548 phospholipid transporter activity IDA
 molecular_functionGO:0008289 lipid binding IEA
 molecular_functionGO:0008429 phosphatidylethanolamine binding IDA
 molecular_functionGO:0008525 phosphatidylcholine transporter activity IDA
 molecular_functionGO:0019992 diacylglycerol binding IDA
 molecular_functionGO:0031210 phosphatidylcholine binding IDA
 molecular_functionGO:0035620 ceramide transporter activity IDA
 molecular_functionGO:0070300 phosphatidic acid binding IDA
 molecular_functionGO:0097001 ceramide binding IDA
 molecular_functionGO:1901611 phosphatidylglycerol binding IDA
 molecular_functionGO:1904121 phosphatidylethanolamine transporter activity IDA
 molecular_functionGO:1990050 phosphatidic acid transporter activity IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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