ENSG00000101134


Homo sapiens

Features
Gene ID: ENSG00000101134
  
Biological name :DOK5
  
Synonyms : docking protein 5 / DOK5 / Q9P104
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 20
Strand: 1
Band: q13.2
Gene start: 54475597
Gene end: 54651171
  
Corresponding Affymetrix probe sets: 1554863_s_at (Human Genome U133 Plus 2.0 Array)   214844_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000262593
Ensembl peptide - ENSP00000379270
NCBI entrez gene - 55816     See in Manteia.
OMIM - 608334
RefSeq - XM_011528904
RefSeq - NM_018431
RefSeq - NM_177959
RefSeq Peptide - NP_808874
RefSeq Peptide - NP_060901
swissprot - Q9P104
Ensembl - ENSG00000101134
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 DOK5ENSGALG00000007786Gallus gallus
 Dok5ENSMUSG00000027560Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
DOK6 / Q6PKX4 / docking protein 6ENSG0000020605270
DOK4 / Q8TEW6 / docking protein 4ENSG0000012517057
DOK1 / Q99704 / docking protein 1ENSG0000011532525
DOK2 / O60496 / docking protein 2ENSG0000014744322
DOK3 / Q7L591 / docking protein 3ENSG0000014609421


Protein motifs (from Interpro)
Interpro ID Name
 IPR001849  Pleckstrin homology domain
 IPR002404  IRS-type PTB domain
 IPR011993  PH-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000165 MAPK cascade IEA
 biological_processGO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway IEA
 biological_processGO:0007399 nervous system development IEA
 biological_processGO:0007411 axon guidance TAS
 biological_processGO:0051386 regulation of neurotrophin TRK receptor signaling pathway IMP
 cellular_componentGO:0005829 cytosol TAS
 molecular_functionGO:0005057 obsolete signal transducer activity, downstream of receptor IEA


Pathways (from Reactome)
Pathway description
RET signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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contact: otassy@igbmc.fr