ENSG00000125170


Homo sapiens

Features
Gene ID: ENSG00000125170
  
Biological name :DOK4
  
Synonyms : docking protein 4 / DOK4 / Q8TEW6
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 16
Strand: -1
Band: q21
Gene start: 57471922
Gene end: 57487327
  
Corresponding Affymetrix probe sets: 207747_s_at (Human Genome U133 Plus 2.0 Array)   209690_s_at (Human Genome U133 Plus 2.0 Array)   209691_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000457670
Ensembl peptide - ENSP00000458037
Ensembl peptide - ENSP00000457971
Ensembl peptide - ENSP00000457730
Ensembl peptide - ENSP00000344277
Ensembl peptide - ENSP00000454738
Ensembl peptide - ENSP00000455128
Ensembl peptide - ENSP00000455528
Ensembl peptide - ENSP00000455566
Ensembl peptide - ENSP00000456590
Ensembl peptide - ENSP00000456739
Ensembl peptide - ENSP00000456864
Ensembl peptide - ENSP00000457188
Ensembl peptide - ENSP00000457192
Ensembl peptide - ENSP00000457212
Ensembl peptide - ENSP00000457621
NCBI entrez gene - 55715     See in Manteia.
OMIM - 608333
RefSeq - XM_005256042
RefSeq - XM_005256043
RefSeq - NM_018110
RefSeq - NM_001330556
RefSeq Peptide - NP_060580
RefSeq Peptide - NP_001317485
swissprot - H3BST9
swissprot - H3BTI4
swissprot - A0A1B0GX86
swissprot - H3BTK2
swissprot - H3BV67
swissprot - H3BVB4
swissprot - Q8TEW6
swissprot - H3BTI7
swissprot - A0A024R6S2
swissprot - H3BN90
swissprot - H3BPY9
swissprot - H3BQ19
swissprot - H3BS85
swissprot - H3BSK0
Ensembl - ENSG00000125170
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dok4ENSDARG00000073731Danio rerio
 DOK4ENSGALG00000001160Gallus gallus
 Dok4ENSMUSG00000040631Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
DOK6 / Q6PKX4 / docking protein 6ENSG0000020605255
DOK5 / Q9P104 / docking protein 5ENSG0000010113448
DOK1 / Q99704 / docking protein 1ENSG0000011532522
DOK3 / Q7L591 / docking protein 3ENSG0000014609419
DOK2 / O60496 / docking protein 2ENSG0000014744319


Protein motifs (from Interpro)
Interpro ID Name
 IPR001849  Pleckstrin homology domain
 IPR002404  IRS-type PTB domain
 IPR011993  PH-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000165 MAPK cascade IEA
 biological_processGO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway IEA
 biological_processGO:0007399 nervous system development IEA
 biological_processGO:0007411 axon guidance TAS
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005829 cytosol TAS
 molecular_functionGO:0005057 obsolete signal transducer activity, downstream of receptor IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
RET signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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