ENSG00000101146


Homo sapiens

Features
Gene ID: ENSG00000101146
  
Biological name :RAE1
  
Synonyms : P78406 / RAE1 / ribonucleic acid export 1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 20
Strand: 1
Band: q13.31
Gene start: 57351010
Gene end: 57379211
  
Corresponding Affymetrix probe sets: 201558_at (Human Genome U133 Plus 2.0 Array)   211318_s_at (Human Genome U133 Plus 2.0 Array)   211319_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000379182
Ensembl peptide - ENSP00000392097
Ensembl peptide - ENSP00000432698
Ensembl peptide - ENSP00000432609
Ensembl peptide - ENSP00000402924
Ensembl peptide - ENSP00000393264
Ensembl peptide - ENSP00000360286
Ensembl peptide - ENSP00000379181
NCBI entrez gene - 8480     See in Manteia.
OMIM - 603343
RefSeq - XM_005260583
RefSeq - XM_005260582
RefSeq - XM_011529089
RefSeq - XM_011529088
RefSeq - NM_001015885
RefSeq - NM_003610
RefSeq - XM_017028108
RefSeq - XM_011529087
RefSeq Peptide - NP_003601
RefSeq Peptide - NP_001015885
swissprot - P78406
swissprot - E9PQ57
swissprot - B0QZ36
swissprot - B0QZ37
swissprot - E9PPG9
Ensembl - ENSG00000101146
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rae1ENSDARG00000007196Danio rerio
 RAE1ENSGALG00000007653Gallus gallus
 Rae1ENSMUSG00000027509Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
BUB3 / O43684 / BUB3, mitotic checkpoint proteinENSG0000015447331


Protein motifs (from Interpro)
Interpro ID Name
 IPR001680  WD40 repeat
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR017986  WD40-repeat-containing domain
 IPR019775  WD40 repeat, conserved site
 IPR020472  G-protein beta WD-40 repeat
 IPR036322  WD40-repeat-containing domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery IBA
 biological_processGO:0006110 regulation of glycolytic process TAS
 biological_processGO:0006405 RNA export from nucleus IBA
 biological_processGO:0006406 mRNA export from nucleus IEA
 biological_processGO:0006409 tRNA export from nucleus TAS
 biological_processGO:0006606 protein import into nucleus IBA
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0007077 mitotic nuclear envelope disassembly TAS
 biological_processGO:0016032 viral process TAS
 biological_processGO:0016925 protein sumoylation TAS
 biological_processGO:0019083 viral transcription TAS
 biological_processGO:0051301 cell division IEA
 biological_processGO:0060236 regulation of mitotic spindle organization IMP
 biological_processGO:0060964 regulation of gene silencing by miRNA TAS
 biological_processGO:0071407 cellular response to organic cyclic compound IEA
 biological_processGO:0075733 intracellular transport of virus TAS
 biological_processGO:1900034 regulation of cellular response to heat TAS
 cellular_componentGO:0000922 spindle pole IEA
 cellular_componentGO:0001650 fibrillar center IDA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005634 nucleus TAS
 cellular_componentGO:0005635 nuclear envelope TAS
 cellular_componentGO:0005643 nuclear pore TAS
 cellular_componentGO:0005737 cytoplasm TAS
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0043657 host cell IEA
 cellular_componentGO:0097431 mitotic spindle pole IMP
 molecular_functionGO:0003723 RNA binding IDA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0008017 microtubule binding ISS
 molecular_functionGO:0043130 ubiquitin binding IBA


Pathways (from Reactome)
Pathway description
ISG15 antiviral mechanism
Transport of the SLBP independent Mature mRNA
Transport of the SLBP Dependant Mature mRNA
Transport of Mature mRNA Derived from an Intronless Transcript
Transport of Mature mRNA derived from an Intron-Containing Transcript
Rev-mediated nuclear export of HIV RNA
Transport of Ribonucleoproteins into the Host Nucleus
NS1 Mediated Effects on Host Pathways
Viral Messenger RNA Synthesis
NEP/NS2 Interacts with the Cellular Export Machinery
Regulation of Glucokinase by Glucokinase Regulatory Protein
Nuclear import of Rev protein
Vpr-mediated nuclear import of PICs
snRNP Assembly
SUMOylation of DNA damage response and repair proteins
SUMOylation of ubiquitinylation proteins
Nuclear Pore Complex (NPC) Disassembly
Regulation of HSF1-mediated heat shock response
SUMOylation of SUMOylation proteins
SUMOylation of chromatin organization proteins
SUMOylation of RNA binding proteins
SUMOylation of DNA replication proteins
Transcriptional regulation by small RNAs
tRNA processing in the nucleus


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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