| MP:0000160 | kyphosis | "forward curvature of the spine, characterized by extensive flexion. " [J:62023, J:66943, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, cml:Cathleen M. Lutz , Mouse Genome Informatics Curator] |
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Allelic Composition: Bub3tm1Jvd/Bub3tm1Jvd
Genetic Background: Not Specified
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| MP:0000162 | lordosis | "anteriorly convex curvature of the spine, "saddle back" " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:62022] |
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Allelic Composition: Bub3tm1Jvd/Bub3tm1Jvd
Genetic Background: Not Specified
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| MP:0000352 | decreased cell proliferation | "less than the normal growth and reproduction of similar cells" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Bub3tm1Jvd/Bub3tm1Jvd
Genetic Background: Not Specified
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| MP:0000749 | muscle degeneration | "pathological deterioration of muscle tissue, often accompanied by loss of function" [csmith:Cynthia L. Smith, Mouse Genome Informatics Curator] |
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Allelic Composition: Bub3tm1Jvd/Bub3tm1Jvd
Genetic Background: Not Specified
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| MP:0001244 | thin dermal layer | "reduced thickness of the dermis" [J:65030] |
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Allelic Composition: Bub3tm1Jvd/Bub3tm1Jvd
Genetic Background: Not Specified
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| MP:0001263 | weight loss | "progressive reduction of body weight below normal average for age" [J:45400] |
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Allelic Composition: Bub3tm1Jvd/Bub3tm1Jvd
Genetic Background: Not Specified
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| MP:0001304 | cataracts | "complete or partial opacity of the lens" [J:65031] |
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Allelic Composition: Bub3tm1Jvd/Bub3tm1Jvd
Genetic Background: Not Specified
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| MP:0002269 | muscular atrophy | "a wasting of muscle tissue resulting in a derangement of the muscle fibers; occurs with age, immobilization, weightlessness, malnutrition or denervation" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, cml:Cathleen M. Lutz , Mouse Genome Informatics Curator] |
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Allelic Composition: Bub3tm1Jvd/Bub3tm1Jvd
Genetic Background: Not Specified
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| MP:0003786 | premature aging | "earlier than normal occurence of the normal signs of aging" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:97764] |
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Allelic Composition: Bub3tm1Jvd/Bub3tm1Jvd
Genetic Background: Not Specified
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| MP:0004024 | aneuploidy | "chromosome count is not an exact multiple of the haploid number " [llw2:Linda Washburn , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Bub3tm1Jvd/Bub3tm1Jvd
Genetic Background: Not Specified
Allelic Composition: Bub3tm1Jvd/Bub3+,Rae1tm1Jvd/Rae1+
Genetic Background: Not Specified
|
| MP:0004045 | abnormal cell cycle checkpoint function | "anomaly in the amount of time spent at the points in the cell cycle (end of G1 phase, end of G2 phase, and during metaphase) which prevent the cell from progressing to the next phase when conditions are unfavorable" [smb:Susan M Bello, Mouse Genome Informatics Curator] |
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Allelic Composition: Bub3tm1Jvd/Bub3tm1Jvd
Genetic Background: Not Specified
Allelic Composition: Bub3tm1Jvd/Bub3+,Rae1tm1Jvd/Rae1+
Genetic Background: Not Specified
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| MP:0004046 | abnormal mitosis | "anomaly in the process of cell division including both division of the nucleus (karyokinesis) and the cytoplasm (cytokinesis) " [smb:Susan M Bello, Mouse Genome Informatics Curator] |
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Allelic Composition: Bub3tm1Jvd/Bub3tm1Jvd
Genetic Background: Not Specified
Allelic Composition: Bub3tm1Jvd/Bub3+,Rae1tm1Jvd/Rae1+
Genetic Background: Not Specified
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| MP:0004499 | increased incidence of chemically-induced tumors | "higher than normal frequency of tumor incidence induced by one or more chemical carcinogens or mutagens" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Bub3tm1Jvd/Bub3tm1Jvd
Genetic Background: Not Specified
Allelic Composition: Bub3tm1Jvd/Bub3+,Rae1tm1Jvd/Rae1+
Genetic Background: Not Specified
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| MP:0004965 | inner cell mass degeneration | |
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Allelic Composition: Bub3tm1Jvd/Bub3tm1Jvd
Genetic Background: Not Specified
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| MP:0005150 | cachexia | "general weight loss and wasting occurring in the course of chronic disease" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Bub3tm1Jvd/Bub3tm1Jvd
Genetic Background: Not Specified
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| MP:0008007 | abnormal cellular replicative senescence | "anomaly in the process in which a cell progresses from its inception to the end of its lifespan, which occurs as the cell continues cycles of growth and division" [GO:0001302, MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Bub3tm1Jvd/Bub3+,Rae1tm1Jvd/Rae1+
Genetic Background: Not Specified
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| MP:0008844 | decreased subcutaneous adipose tissue amount | "reduction in amount of adipose tissue beneath the skin" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Bub3tm1Jvd/Bub3+,Rae1tm1Jvd/Rae1+
Genetic Background: Not Specified
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| MP:0010025 | decreased total body fat amount | "less than the normal total amount of connective tissue composed of fat cells within the entire body" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Bub3tm1Jvd/Bub3+,Rae1tm1Jvd/Rae1+
Genetic Background: Not Specified
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| MP:0011096 | complete embryonic lethality before somite formation | "death of all organisms of a given genotype in a population between the point of implantation and somite formation (Mus: E4.5 to less than E8)" [MGI:csmith] |
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Allelic Composition: Bub3tm1Jvd/Bub3tm1Jvd
Genetic Background: Not Specified
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