ENSG00000101307


Homo sapiens

Features
Gene ID: ENSG00000101307
  
Biological name :SIRPB1
  
Synonyms : O00241 / Q5TFQ8 / signal regulatory protein beta 1 / SIRPB1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 20
Strand: -1
Band: p13
Gene start: 1563521
Gene end: 1620061
  
Corresponding Affymetrix probe sets: 1554624_a_at (Human Genome U133 Plus 2.0 Array)   206934_at (Human Genome U133 Plus 2.0 Array)   217240_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000457855
Ensembl peptide - ENSP00000457458
Ensembl peptide - ENSP00000457829
Ensembl peptide - ENSP00000262929
Ensembl peptide - ENSP00000279477
Ensembl peptide - ENSP00000371016
Ensembl peptide - ENSP00000371018
Ensembl peptide - ENSP00000455568
Ensembl peptide - ENSP00000456351
Ensembl peptide - ENSP00000456519
Ensembl peptide - ENSP00000456747
Ensembl peptide - ENSP00000456826
Ensembl peptide - ENSP00000457323
NCBI entrez gene - 10326     See in Manteia.
OMIM - 603889
RefSeq - XM_017027585
RefSeq - NM_006065
RefSeq - XM_005260641
RefSeq - XM_005260643
RefSeq - XM_005260644
RefSeq - XM_011529130
RefSeq - XM_011529134
RefSeq - XM_017027577
RefSeq - XM_017027578
RefSeq - XM_017027579
RefSeq - XM_017027580
RefSeq - XM_017027581
RefSeq - XM_017027582
RefSeq - XM_017027583
RefSeq - XM_017027584
RefSeq - NM_001083910
RefSeq - NM_001135844
RefSeq - NM_001330639
RefSeq Peptide - NP_006056
RefSeq Peptide - NP_001077379
RefSeq Peptide - NP_001129316
RefSeq Peptide - NP_001316086
RefSeq Peptide - NP_001317568
swissprot - H9KV29
swissprot - H3BRP9
swissprot - Q5TFQ8
swissprot - H3BQ21
swissprot - O00241
swissprot - H3BSK5
swissprot - H3BTT9
swissprot - H3BU43
swissprot - H3BUW0
Ensembl - ENSG00000101307
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Gm5150ENSMUSG00000078780Mus musculus
 Gm9733ENSMUSG00000078783Mus musculus
 SirpaENSMUSG00000037902Mus musculus
 Sirpb1aENSMUSG00000095788Mus musculus
 Sirpb1bENSMUSG00000095028Mus musculus
 Sirpb1cENSMUSG00000074677Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SIRPA / P78324 / signal regulatory protein alphaENSG0000019805378
SIRPG / Q9P1W8 / signal regulatory protein gammaENSG0000008901275
AL049634.2ENSG0000026086138
Q5JXA9 / SIRPB2 / signal regulatory protein beta 2ENSG0000019620919
SIRPD / Q9H106 / signal regulatory protein deltaENSG0000012590019


Protein motifs (from Interpro)
Interpro ID Name
 IPR003597  Immunoglobulin C1-set
 IPR003599  Immunoglobulin subtype
 IPR007110  Immunoglobulin-like domain
 IPR013106  Immunoglobulin V-set domain
 IPR013783  Immunoglobulin-like fold
 IPR036179  Immunoglobulin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction TAS
 biological_processGO:0007166 cell surface receptor signaling pathway TAS
 biological_processGO:0043312 neutrophil degranulation TAS
 biological_processGO:0045087 innate immune response TAS
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030667 secretory granule membrane TAS
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
DAP12 interactions
Signal regulatory protein family interactions
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000011600 O43914 / TYROBP / TYRO protein tyrosine kinase binding protein  / reaction / complex






 

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