ENSG00000089012


Homo sapiens

Features
Gene ID: ENSG00000089012
  
Biological name :SIRPG
  
Synonyms : Q9P1W8 / signal regulatory protein gamma / SIRPG
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 20
Strand: -1
Band: p13
Gene start: 1629152
Gene end: 1657779
  
Corresponding Affymetrix probe sets: 220485_s_at (Human Genome U133 Plus 2.0 Array)   234742_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000370992
Ensembl peptide - ENSP00000216927
Ensembl peptide - ENSP00000305529
Ensembl peptide - ENSP00000370995
Ensembl peptide - ENSP00000342759
NCBI entrez gene - 55423     See in Manteia.
OMIM - 605466
RefSeq - XM_011529286
RefSeq - NM_001039508
RefSeq - NM_018556
RefSeq - NM_080816
RefSeq - XM_005260749
RefSeq Peptide - NP_543006
RefSeq Peptide - NP_001034597
RefSeq Peptide - NP_061026
swissprot - Q9P1W8
Ensembl - ENSG00000089012
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Gm5150ENSMUSG00000078780Mus musculus
 Gm9733ENSMUSG00000078783Mus musculus
 SirpaENSMUSG00000037902Mus musculus
 Sirpb1aENSMUSG00000095788Mus musculus
 Sirpb1bENSMUSG00000095028Mus musculus
 Sirpb1cENSMUSG00000074677Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
O00241 / Q5TFQ8 / SIRPB1 / signal regulatory protein beta 1ENSG0000010130778
SIRPA / P78324 / signal regulatory protein alphaENSG0000019805373
AL049634.2ENSG0000026086132
Q5JXA9 / SIRPB2 / signal regulatory protein beta 2ENSG0000019620919
SIRPD / Q9H106 / signal regulatory protein deltaENSG0000012590019


Protein motifs (from Interpro)
Interpro ID Name
 IPR003597  Immunoglobulin C1-set
 IPR003599  Immunoglobulin subtype
 IPR007110  Immunoglobulin-like domain
 IPR013106  Immunoglobulin V-set domain
 IPR013783  Immunoglobulin-like fold
 IPR036179  Immunoglobulin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0007267 cell-cell signaling TAS
 biological_processGO:0008284 positive regulation of cell proliferation IDA
 biological_processGO:0008285 negative regulation of cell proliferation TAS
 biological_processGO:0022409 positive regulation of cell-cell adhesion IDA
 biological_processGO:0035556 intracellular signal transduction TAS
 biological_processGO:0050870 positive regulation of T cell activation IDA
 biological_processGO:0050900 leukocyte migration TAS
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Cell surface interactions at the vascular wall
Signal regulatory protein family interactions


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000196776 CD47 / Q08722 / CD47 molecule  / reaction / complex






 

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