ENSG00000196776


Homo sapiens

Features
Gene ID: ENSG00000196776
  
Biological name :CD47
  
Synonyms : CD47 / CD47 molecule / Q08722
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: -1
Band: q13.12
Gene start: 108043094
Gene end: 108091862
  
Corresponding Affymetrix probe sets: 211075_s_at (Human Genome U133 Plus 2.0 Array)   213055_at (Human Genome U133 Plus 2.0 Array)   213856_at (Human Genome U133 Plus 2.0 Array)   213857_s_at (Human Genome U133 Plus 2.0 Array)   226016_at (Human Genome U133 Plus 2.0 Array)   227259_at (Human Genome U133 Plus 2.0 Array)   242974_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000355361
Ensembl peptide - ENSP00000430843
Ensembl peptide - ENSP00000493750
Ensembl peptide - ENSP00000347512
Ensembl peptide - ENSP00000381309
NCBI entrez gene - 961     See in Manteia.
OMIM - 601028
RefSeq - XM_005247909
RefSeq - NM_001777
RefSeq - NM_198793
RefSeq - XM_005247908
RefSeq Peptide - NP_001768
RefSeq Peptide - NP_942088
swissprot - H7BYS8
swissprot - Q08722
swissprot - H0YC40
Ensembl - ENSG00000196776
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CD47ENSGALG00000015355Gallus gallus
 Cd47ENSMUSG00000055447Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR006704  Leukocyte surface antigen CD47
 IPR007110  Immunoglobulin-like domain
 IPR013147  CD47 transmembrane
 IPR013270  CD47 immunoglobulin-like
 IPR013783  Immunoglobulin-like fold
 IPR036179  Immunoglobulin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0007229 integrin-mediated signaling pathway TAS
 biological_processGO:0008228 opsonization IEA
 biological_processGO:0008284 positive regulation of cell proliferation IDA
 biological_processGO:0009617 response to bacterium IEA
 biological_processGO:0022409 positive regulation of cell-cell adhesion IDA
 biological_processGO:0030198 extracellular matrix organization TAS
 biological_processGO:0043312 neutrophil degranulation TAS
 biological_processGO:0050729 positive regulation of inflammatory response IEA
 biological_processGO:0050766 positive regulation of phagocytosis IEA
 biological_processGO:0050870 positive regulation of T cell activation IDA
 biological_processGO:0050900 leukocyte migration TAS
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0035579 specific granule membrane TAS
 cellular_componentGO:0070062 extracellular exosome IEA
 cellular_componentGO:0070821 tertiary granule membrane TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0070053 thrombospondin receptor activity IPI


Pathways (from Reactome)
Pathway description
Cell surface interactions at the vascular wall
Integrin cell surface interactions
Signal regulatory protein family interactions
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000105664 COMP / P49747 / cartilage oligomeric matrix protein  / reaction / complex
 ENSG00000089012 SIRPG / Q9P1W8 / signal regulatory protein gamma  / reaction / complex
 ENSG00000111679 PTPN6 / P29350 / protein tyrosine phosphatase, non-receptor type 6  / reaction / complex
 ENSG00000005020 SKAP2 / O75563 / src kinase associated phosphoprotein 2  / complex / reaction
 ENSG00000177885 GRB2 / P62993 / growth factor receptor bound protein 2  / complex / reaction
 ENSG00000120899 PTK2B / Q14289 / protein tyrosine kinase 2 beta  / reaction / complex
 ENSG00000179295 PTPN11 / Q06124 / protein tyrosine phosphatase, non-receptor type 11  / reaction / complex
 ENSG00000198053 SIRPA / P78324 / signal regulatory protein alpha  / reaction / complex
 ENSG00000082074 FYB1 / O15117 / FYN binding protein 1  / reaction / complex
 ENSG00000197122 SRC / P12931 / SRC proto-oncogene, non-receptor tyrosine kinase  / reaction






 

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