ENSMUSG00000055447


Mus musculus

Features
Gene ID: ENSMUSG00000055447
  
Biological name :Cd47
  
Synonyms : Cd47 / Leukocyte surface antigen CD47 / Q61735
  
Possible biological names infered from orthology : CD47 molecule / Q08722
  
Species: Mus musculus
  
Chr. number: 16
Strand: 1
Band: B5
Gene start: 49800533
Gene end: 49915010
  
Corresponding Affymetrix probe sets: 10436182 (MoGene1.0st)   10436196 (MoGene1.0st)   1419554_at (Mouse Genome 430 2.0 Array)   1428187_at (Mouse Genome 430 2.0 Array)   1430997_at (Mouse Genome 430 2.0 Array)   1449507_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000155699
Ensembl peptide - ENSMUSP00000155856
Ensembl peptide - ENSMUSP00000099853
Ensembl peptide - ENSMUSP00000110140
Ensembl peptide - ENSMUSP00000154914
Ensembl peptide - ENSMUSP00000155178
Ensembl peptide - ENSMUSP00000155289
Ensembl peptide - ENSMUSP00000155544
Ensembl peptide - ENSMUSP00000155684
NCBI entrez gene - 16423     See in Manteia.
MGI - MGI:96617
RefSeq - NM_010581
RefSeq - XM_006521811
RefSeq - XM_006521808
RefSeq - XM_006521809
RefSeq - XM_006521810
RefSeq - XM_006521806
RefSeq - XM_006521807
RefSeq Peptide - NP_034711
swissprot - Q61735
swissprot - D3Z187
Ensembl - ENSMUSG00000055447
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CD47ENSGALG00000015355Gallus gallus
 CD47ENSG00000196776Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR006704  Leukocyte surface antigen CD47
 IPR007110  Immunoglobulin-like domain
 IPR013147  CD47 transmembrane
 IPR013270  CD47 immunoglobulin-like
 IPR013783  Immunoglobulin-like fold


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0008228 opsonization IDA
 biological_processGO:0008284 positive regulation of cell proliferation IEA
 biological_processGO:0009617 response to bacterium IMP
 biological_processGO:0022409 positive regulation of cell-cell adhesion IEA
 biological_processGO:0050729 positive regulation of inflammatory response IMP
 biological_processGO:0050766 positive regulation of phagocytosis IDA
 biological_processGO:0050870 positive regulation of T cell activation IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0070062 extracellular exosome IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0070053 thrombospondin receptor activity IEA


Pathways (from Reactome)
Pathway description
Cell surface interactions at the vascular wall
Integrin cell surface interactions
Signal regulatory protein family interactions
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000208 decreased hematocrit "less than the average percentage of a volume of a blood sample occupied by red blood cells" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Cd47tm1Fpl/Cd47tm1Fpl
Genetic Background: C.129S7-Cd47tm1Fpl

Allelic Composition: Cd47tm1Fpl/Cd47tm1Fpl
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0000221 decreased WBC count "fewer than normal numbers of WBCs" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Cd47tm1Fpl/Cd47tm1Fpl
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0000222 decreased neutrophil count "fewer than normal neutrophil numbers" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Cd47tm1Fpl/Cd47tm1Fpl
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0000245 abnormal erythropoiesis "atypical process of red blood cell formation" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, tc:Teresa Chu , Mouse Genome Informatics Curator]
Show

Allelic Composition: Cd47tm1Fpl/Cd47tm1Fpl
Genetic Background: C.129S7-Cd47tm1Fpl

 MP:0000321 increased bone marrow cell number "increased number of cells that make up the core cavitites of bones when compared to the norm" [tc:Teresa Chu , Mouse Genome Informatics Curator]
Show

Allelic Composition: Cd47tm1Fpl/Cd47tm1Fpl
Genetic Background: C.129S7-Cd47tm1Fpl

 MP:0000556 abnormal hindlimb morphology "malformation of the entire posterior extremities" [MGI:tc]
Show

Allelic Composition: Aldh1a2tm1Gdu/Aldh1a2tm1Gdu
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0000689 abnormal spleen morphology "atypical structure of the organ that functions to filter blood and to store red corpuscles and platelets" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:27463]
Show

Allelic Composition: Cd47tm1Fpl/Cd47tm1Fpl
Genetic Background: C.129S7-Cd47tm1Fpl

 MP:0000691 enlarged spleen "increased spleen size" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Cd47tm1Fpl/Cd47tm1Fpl
Genetic Background: C.129S7-Cd47tm1Fpl

 MP:0001204 skin irradiation resistance "decreased incidence of aberrant or damaged cells due to irradiation induced genotoxic damage" [J:65162]
Show

Allelic Composition: Cd47tm1Fpl/Cd47tm1Fpl
Genetic Background: C.129S7-Cd47tm1Fpl

 MP:0001533 abnormal skeleton physiology "anomalous function of the bony framework of the body" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Cd47tm1Fpl/Cd47tm1Fpl
Genetic Background: C.129S7-Cd47tm1Fpl

 MP:0001585 hemolytic anemia "an anemic condition resulting from an increased rate of erythrocyte destruction" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Cd47tm1Fpl/Cd47tm1Fpl
Genetic Background: C.129S7-Cd47tm1Fpl

 MP:0001829 increased activated T cell number "greater than normal numbers of effector T cells" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Trim62tm1Akil/Trim62+
Genetic Background: involves: 129S/SvEv * C57BL/6

 MP:0002052 decreased tumor incidence "less than the expected number of abnormal growths in a specific population" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Cd47tm1Fpl/Cd47tm1Fpl
Genetic Background: C.129S7-Cd47tm1Fpl

 MP:0002083 premature death "death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Cd47tm1Fpl/Cd47tm1Fpl
Genetic Background: C.129S7-Cd47tm1Fpl

 MP:0002412 increased susceptibility to bacterial infection "greater likelihood that an organism will develop ill effects from a bacterial infection or from components of or toxins produced by bacteria" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Dstdt-39J/Dstdt-39J
Genetic Background: involves: NOD

Allelic Composition: Cd47tm1Fpl/Cd47tm1Fpl
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0002418 increased susceptibility to viral infection "greater likelihood that an organism will develop ill effects from a viral infection or from components of or toxins produced by a virus" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Trim62tm1Akil/Trim62+
Genetic Background: involves: 129S/SvEv * C57BL/6

 MP:0002463 abnormal neutrophil physiology "abnormal function of these granular leukocytes, which stain with neutral dyes" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Dstdt-39J/Dstdt-39J
Genetic Background: involves: NOD

 MP:0002467 impaired neutrophil phagocytosis "reduced ability of these leukocytes to internalize particulate matter" [Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Dstdt-39J/Dstdt-39J
Genetic Background: involves: NOD

 MP:0002573 behavioral despair "depression assayed by reduced escape attempts and/or immobility when placed in a stressful situation such as a forced swim test or a suspension test; or failure to seek pleasurable stimuli" [J:80395]
Show

Allelic Composition: Dstdt-39J/Dstdt-39J
Genetic Background: involves: NOD

 MP:0002626 increased heart rate "greater than average resting heart beats per minute" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
Show

Allelic Composition: Cd47tm1Fpl/Cd47tm1Fpl
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0002640 reticulocytosis "an increase in the number of reticulocytes in the blood" [J:78271, cwg:Carroll W. Goldsmith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Cd47tm1Fpl/Cd47tm1Fpl
Genetic Background: C.129S7-Cd47tm1Fpl

 MP:0002799 abnormal passive avoidance behavior "defects in the ability of an animal to enter an hostile environment where it receives a unpleasant or punishing stimuli applied previously with prolonged latency" [CFG:Center for Functional Genomics , Northwestern University]
Show

Allelic Composition: Abl1tm1.1Gcos/Abl1+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0002874 decreased hemoglobin content "decrease in the total hemoglobin content in the circulating blood" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Cd47tm1Fpl/Cd47tm1Fpl
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0002912 abnormal excitatory postsynaptic potential "defect in the potential detected in postsynaptic cells when an excitatory impulse arrives at the synapse causing depolarization" [Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3]
Show

Allelic Composition: Cd47tm1Fpl/Cd47tm1Fpl
Genetic Background: C.129S7-Cd47tm1Fpl

 MP:0003179 decreased platelet count "fewer than the normal numbers of the non-nucleated cells found in the blood and involved in blood coagulation " [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, hdene:Howard Dene , Mouse Genome Informatics Curator, J:93052]
Show

Allelic Composition: Dstdt-39J/Dstdt-39J
Genetic Background: involves: NOD

Allelic Composition: Cd47tm1Fpl/Cd47tm1Fpl
Genetic Background: C.129S7-Cd47tm1Fpl

 MP:0003710 abnormal physiological neovascularization "anomalies in the development of new blood vessels in restoration of blood circulation during the healing process " [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Aldh1a2tm1Gdu/Aldh1a2tm1Gdu
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0003795 abnormal bone structure 
Show

Allelic Composition: Cd47tm1Fpl/Cd47tm1Fpl
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0004087 abnormal muscle fiber morphology "malformed or poorly developed muscle fibers, the cylindrical multinucleated muscle cells that contract when stimulated" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Cd47tm1Fpl/Cd47tm1Fpl
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0004875 increased mean arterial blood pressure "increase in the average arterial pressure during a single cardiac cycle" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Cd47tm1Fpl/Cd47tm1Fpl
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0004985 decreased osteoclast cell number "reduced number of the bone resorpting cells that remove bone tissue by degrading the mineralized matrix" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Dstdt-39J/Dstdt-39J
Genetic Background: involves: NOD

Allelic Composition: Cd47tm1Fpl/Cd47tm1Fpl
Genetic Background: C.129S7-Cd47tm1Fpl

 MP:0004993 decreased bone resorption "reduced amount of degradation of the organic and inorganic phases of bone by absorption, usually by the abnormal function or number of osteoclasts" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Cd47tm1Fpl/Cd47tm1Fpl
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0005016 decreased lymphocyte number "fewer than normal white blood cell numbers " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Rag2tm1Fwa/Rag2tm1Fwa,Cd47tm1Fpl/Cd47tm1Fpl,Il2rgtm1Cgn/Y
Genetic Background: involves: 129P2/OlaHsd * 129S/SvEv * 129S7/SvEvBrd * C57BL/6

 MP:0005018 decreased T cell number "fewer than normal T cell numbers" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Aldh1a2tm1Gdu/Aldh1a2tm1Gdu
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0005074 defective granulocyte bactericidal activity "inability or reduced ability of neutrophils, eosinophils, or basophils to kill bacteria" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, J:5405]
Show

Allelic Composition: Dstdt-39J/Dstdt-39J
Genetic Background: involves: NOD

 MP:0005404 abnormal axon morphology "anomaly in the structure of the single process of a nerve cell that normally conducts impulses away from the cell body" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Aldh1a2tm1Gdu/Aldh1a2tm1Gdu
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0005464 abnormal platelet physiology "atypical response of the non-nucleated cells found in the blood and involved in blood coagulation" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Dstdt-39J/Dstdt-39J
Genetic Background: involves: NOD

Allelic Composition: Cd47tm1Fpl/Cd47tm1Fpl
Genetic Background: C.129S7-Cd47tm1Fpl

 MP:0005501 abnormal skin physiology "atypical function of the membranous protective covering of the body" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Aldh1a2tm1Gdu/Aldh1a2tm1Gdu
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0005673 decreased susceptibility to graft versus host disease "less likelihood of developing clinical symptoms of anorexia, diarrhea, loss of hair, leukopenia, thrombocytopenia, growth retardation, and eventual death brought about by the a graft versus host reaction, which is an immunological attack mounted by a graft against the host because of tissue incompatibility when immunologically competent cells are transplanted to an immunologically incompetent host" [MeSH:National Library of Medicine - Medical Subject Headings, 2003, cwg:Carroll-Ann W. Goldsmith, Mouse Genome Informatics curator, J:52834]
Show

Allelic Composition: Rag2tm1Fwa/Rag2tm1Fwa,Cd47tm1Fpl/Cd47tm1Fpl,Il2rgtm1Cgn/Y
Genetic Background: involves: 129P2/OlaHsd * 129S/SvEv * 129S7/SvEvBrd * C57BL/6

 MP:0006036 abnormal mitochondrial physiology 
Show

Allelic Composition: Aldh1a2tm1Gdu/Aldh1a2tm1Gdu
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0006080 CNS ischemia "abnormal incidence of or response to loss of circulation in a region of the brain; may be induced or spontaneous" [smb:Susan M Bello, Mouse Genome Informatics Curator, ncbi:NCBI request]
Show

Allelic Composition: Aldh1a2tm1Gdu/Aldh1a2tm1Gdu
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0006143 increased diastolic blood pressure "abnormal increase in the pressure in the arteries between heart beats when the heart is relaxed" [ncbi:Matthew Mailman, NCBI request, smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Cd47tm1Fpl/Cd47tm1Fpl
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0006144 increased systolic blood pressure "abnormal increase in the pressure in the arteries as the heart contracts and pumps blood into the arteries" [ncbi:Matthew Mailman, NCBI request, smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Cd47tm1Fpl/Cd47tm1Fpl
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0008075 decreased CD4-positive T cell number "reduced number of the subset of T lymphocytes that carry the CD4 marker, recognize intravesicular peptides bound to MHC class-II molecules, and turn on antibody production" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Rag2tm1Fwa/Rag2tm1Fwa,Cd47tm1Fpl/Cd47tm1Fpl,Il2rgtm1Cgn/Y
Genetic Background: involves: 129P2/OlaHsd * 129S/SvEv * 129S7/SvEvBrd * C57BL/6

 MP:0008078 increased CD8-positive T cell number "greater number of the regulatory subset of T lymphocytes that are involved in MHC class I restricted interactions" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Rag2tm1Fwa/Rag2tm1Fwa,Cd47tm1Fpl/Cd47tm1Fpl,Il2rgtm1Cgn/Y
Genetic Background: involves: 129P2/OlaHsd * 129S/SvEv * 129S7/SvEvBrd * C57BL/6

 MP:0008143 abnormal dendrite morphology "any structural anomaly of the highly branched tree-like process of a neuron that serves as a receptive field and conducts impulses toward the cell body" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator", MGI:rbabiuk "Randall Babiuk, Mouse Genome Informatics Curator"]
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Allelic Composition: Aldh1a2tm1Gdu/Aldh1a2tm1Gdu
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0008396 abnormal osteoclast differentiation "atypical production of or inability to produce bone resorpting cells that remove bone tissue by degrading the mineralized matrix" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Cd47tm1Fpl/Cd47tm1Fpl
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0008464 absent peripheral lymph nodes "absence of the lymph nodes located outside the thoracic and abdominal cavities, such as the submandibular, prescapular, axillary, inguinal and popliteal lymph nodes" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Rag2tm1Fwa/Rag2tm1Fwa,Cd47tm1Fpl/Cd47tm1Fpl,Il2rgtm1Cgn/Y
Genetic Background: involves: 129P2/OlaHsd * 129S/SvEv * 129S7/SvEvBrd * C57BL/6

 MP:0008713 abnormal cytokine level "deviation from the normal levels of any of the non-antibody proteins made by inflammatory leukocytes and some non-leukocytic cells that affect the behavior of other cells" [ISBN:0-8153-1691-7 "Immunobiology, The Immune System in Health and Disease", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Cd47tm1Fpl/Cd47tm1Fpl
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0008719 impaired neutrophil recruitment "reduced diffusion or accumulation of neutrophils in tissues or cells in response to a wide variety of substances released at the sites of inflammatory reactions" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Aldh1a2tm1Gdu/Aldh1a2tm1Gdu
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0008720 impaired neutrophil migration "defect in the ability of neutrophils to move along a chemotactic gradient" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Dstdt-39J/Dstdt-39J
Genetic Background: involves: NOD

 MP:0008752 abnormal tumor necrosis factor level "deviation from the normal levels of a serum glycoprotein produced by activated macrophages and NK cells and involved in initiating local inflammatory responses, particularly by its action on the endothelium of local blood vessels; its actions result in increased vascular permeability and induction of expression of adhesion molecules on the endothelium" [MESH:D12.644.276.374.500.800]
Show

Allelic Composition: Cd47tm1Fpl/Cd47tm1Fpl
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0008826 abnormal splenic cell ratio "deviation from the standard ratios of splenocyte subpopulations compared to control samples" [MGI:mberry "Melissa Berry, Genetics Resources Curator"]
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Allelic Composition: Cd47tm1Fpl/Cd47tm1Fpl
Genetic Background: C.129S7-Cd47tm1Fpl

 MP:0009347 increased cancellous bone thickness "thicker than normal bone with a lattice-like or spongy structure" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Cd47tm1Fpl/Cd47tm1Fpl
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0009788 increased susceptibility to bacterial infection induced morbidity/mortality "increased likelihood that an organism will display the expected moribund state caused by a bacterial invasion or from components of or toxins produced by bacteria" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Aldh1a2tm1Gdu/Aldh1a2tm1Gdu
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

Allelic Composition: Cd47tm1Fpl/Cd47tm1Fpl
Genetic Background: B6.129S7-Cd47tm1Fpl

 MP:0009789 decreased susceptibility to bacterial infection induced morbidity/mortality "reduced likelihood that an organism will display the expected moribund state caused by a bacterial invasion or from components of or toxins produced by bacteria" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Cd47tm1Fpl/Cd47tm1Fpl
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0010334 pleural effusion "accumulation of excess fluid in the pleural cavity" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Cd47tm1Fpl/Cd47tm1Fpl
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0010878 increased trabecular bone volume "increase in the amount of space occupied by trabecular bone tissue in the skeleton" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Cd47tm1Fpl/Cd47tm1Fpl
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000031849 Comp / Q9R0G6 / Cartilage oligomeric matrix protein / P49747*  / reaction / complex
 ENSMUSG00000059923 Grb2 / Q60631 / Growth factor receptor-bound protein 2 / P62993*  / complex / reaction
 ENSMUSG00000059182 Skap2 / Q3UND0 / Src kinase-associated phosphoprotein 2 / O75563*  / complex / reaction
 ENSMUSG00000022148 Fyb / O35601 / FYN-binding protein 1 / FYB1* / O15117*  / complex / reaction
 ENSMUSG00000059456 Ptk2b / Q9QVP9 / PTK2 protein tyrosine kinase 2 beta / Q14289* / protein tyrosine kinase 2 beta*  / complex / reaction






 

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