ENSG00000101391


Homo sapiens

Features
Gene ID: ENSG00000101391
  
Biological name :CDK5RAP1
  
Synonyms : CDK5RAP1 / CDK5 regulatory subunit associated protein 1 / Q96SZ6
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 20
Strand: -1
Band: q11.21
Gene start: 33358839
Gene end: 33401561
  
Corresponding Affymetrix probe sets: 218315_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000476857
Ensembl peptide - ENSP00000341840
Ensembl peptide - ENSP00000350558
Ensembl peptide - ENSP00000409474
Ensembl peptide - ENSP00000217372
NCBI entrez gene - 51654     See in Manteia.
OMIM - 608200
RefSeq - XM_017027876
RefSeq - NM_001278168
RefSeq - NM_001278169
RefSeq - NM_016082
RefSeq - NM_016408
RefSeq - XM_011528856
RefSeq - XM_011528857
RefSeq - XM_011528858
RefSeq - XM_011528859
RefSeq - XM_011528860
RefSeq - NM_001278167
RefSeq Peptide - NP_001265097
RefSeq Peptide - NP_001265098
RefSeq Peptide - NP_057166
RefSeq Peptide - NP_057492
RefSeq Peptide - NP_001265096
swissprot - H0Y721
swissprot - Q96SZ6
swissprot - A0A0S2Z592
swissprot - A0A0S2Z5J9
Ensembl - ENSG00000101391
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cdk5rap1ENSDARG00000044925Danio rerio
 CDK5RAP1ENSGALG00000006738Gallus gallus
 Q8BTW8ENSMUSG00000027487Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CDKAL1 / Q5VV42 / CDK5 regulatory subunit associated protein 1 like 1ENSG0000014599621


Protein motifs (from Interpro)
Interpro ID Name
 IPR002792  TRAM domain
 IPR005839  Methylthiotransferase
 IPR006463  tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase MiaB
 IPR006638  Elp3/MiaB/NifB
 IPR007197  Radical SAM
 IPR013785  Aldolase-type TIM barrel
 IPR013848  Methylthiotransferase, N-terminal
 IPR020612  Methylthiotransferase, conserved site
 IPR023404  Radical SAM, alpha/beta horseshoe


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity IEA
 biological_processGO:0006400 tRNA modification IEA
 biological_processGO:0007420 brain development NAS
 biological_processGO:0035600 tRNA methylthiolation IEA
 biological_processGO:0045664 regulation of neuron differentiation NAS
 biological_processGO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity TAS
 biological_processGO:0045903 positive regulation of translational fidelity IEA
 biological_processGO:0070131 positive regulation of mitochondrial translation IEA
 biological_processGO:0070900 mitochondrial tRNA modification IEA
 cellular_componentGO:0005575 cellular_component ND
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005739 mitochondrion IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0019901 protein kinase binding NAS
 molecular_functionGO:0035597 N6-isopentenyladenosine methylthiotransferase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0051536 iron-sulfur cluster binding IEA
 molecular_functionGO:0051539 4 iron, 4 sulfur cluster binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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