ENSG00000101608


Homo sapiens

Features
Gene ID: ENSG00000101608
  
Biological name :MYL12A
  
Synonyms : MYL12A / myosin light chain 12A / P19105
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 18
Strand: 1
Band: p11.31
Gene start: 3247481
Gene end: 3256236
  
Corresponding Affymetrix probe sets: 1555976_s_at (Human Genome U133 Plus 2.0 Array)   1555977_at (Human Genome U133 Plus 2.0 Array)   1555978_s_at (Human Genome U133 Plus 2.0 Array)   201318_s_at (Human Genome U133 Plus 2.0 Array)   201319_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000464359
Ensembl peptide - ENSP00000441231
Ensembl peptide - ENSP00000462171
Ensembl peptide - ENSP00000217652
Ensembl peptide - ENSP00000462865
Ensembl peptide - ENSP00000463009
Ensembl peptide - ENSP00000463614
NCBI entrez gene - 10627     See in Manteia.
RefSeq - NM_001303047
RefSeq - NM_001303049
RefSeq - NM_006471
RefSeq - NM_001303048
RefSeq Peptide - NP_001289976
RefSeq Peptide - NP_001289978
RefSeq Peptide - NP_006462
RefSeq Peptide - NP_001289977
swissprot - P19105
swissprot - J3KT92
swissprot - J3KTJ1
swissprot - J3QRS3
Ensembl - ENSG00000101608
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 myl12.2ENSDARG00000025326Danio rerio


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MYL12B / O14950 / myosin light chain 12BENSG0000011868095
MYL2 / P10916 / myosin light chain 2ENSG0000011124553
MYLPF / Q96A32 / myosin light chain, phosphorylatable, fast skeletal muscleENSG0000018020953
MYL5 / Q02045 / myosin light chain 5ENSG0000021537553
MYL10 / Q9BUA6 / myosin light chain 10ENSG0000010643652
MYL7 / Q01449 / myosin light chain 7ENSG0000010663148


Protein motifs (from Interpro)
Interpro ID Name
 IPR002048  EF-hand domain
 IPR011992  EF-hand domain pair
 IPR015070  DJBP, EF-hand domain
 IPR018247  EF-Hand 1, calcium-binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006936 muscle contraction TAS
 biological_processGO:0048013 ephrin receptor signaling pathway TAS
 biological_processGO:0070527 platelet aggregation HMP
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0016459 myosin complex IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Ephrin signaling
Smooth Muscle Contraction


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000077264 PAK3 / O75914 / p21 (RAC1) activated kinase 3  / reaction
 ENSG00000149269 PAK1 / Q13153 / p21 (RAC1) activated kinase 1  / reaction






 

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