ENSDARG00000025326


Danio rerio

Features
Gene ID: ENSDARG00000025326
  
Biological name :myl12.2
  
Synonyms : myl12.2 / myosin, light chain 12, genome duplicate 2
  
Possible biological names infered from orthology : MYL12A / MYL12B / myosin light chain 12A / myosin light chain 12B / Myosin regulatory light chain 12B / O14950 / P19105 / Q3THE2
  
Species: Danio rerio
  
Chr. number: 2
Strand: -1
Band:
Gene start: 30910134
Gene end: 30912922
  
Corresponding Affymetrix probe sets: Dr.20229.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000152171
Ensembl peptide - ENSDARP00000117880
NCBI entrez gene - 337084     See in Manteia.
RefSeq - NM_001130589
RefSeq - NM_001291711
RefSeq Peptide - NP_001124061
RefSeq Peptide - NP_001278640
swissprot - B3DKC6
ZFIN ID - ZDB-GENE-030131-9028
Ensembl - ENSDARG00000025326
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000038635Gallus gallus
 MYL12AENSGALG00000014854Gallus gallus
 MYL12AENSG00000101608Homo sapiens
 MYL12BENSG00000118680Homo sapiens
 Myl12aENSMUSG00000024048Mus musculus
 Myl12bENSMUSG00000034868Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
myl12.1 / myosin, light chain 12, genome duplicate 1ENSDARG0000009976695
myl9b / myosin, light chain 9b, regulatoryENSDARG0000000803094
myl9a / myosin, light chain 9a, regulatory / Myl9* / Q9CQ19* / Myosin regulatory light polypeptide 9 *ENSDARG0000003812392
myl7 / myosin, light chain 7, regulatory / Q01449* / Q9QVP4* / myosin light chain 7* / Myosin regulatory light chain 2, atrial isoform *ENSDARG0000001909656
mylpfa / myosin light chain, phosphorylatable, fast skeletal muscle a / MYLPF* / Q96A32* / P97457* / myosin light chain, phosphorylatable, fast skeletal muscle* / Mus musculus myosin light ...ENSDARG0000005325455
mylpfb / myosin light chain, phosphorylatable, fast skeletal muscle b / MYLPF* / Q96A32* / P97457* / myosin light chain, phosphorylatable, fast skeletal muscle* / Mus musculus myosin light ...ENSDARG0000000258954
myl2b / myosin, light chain 2b, regulatory, cardiac, slow / MYL2* / P10916* / P51667* / myosin light chain 2* / Myosin regulatory light chain 2, ventricular/cardiac muscle isoform *ENSDARG0000005342453
CABZ01076669.1 / MYL2* / P10916* / myosin light chain 2*ENSDARG0000010472253
myl10 / myosin, light chain 10, regulatory / Q9BUA6* / myosin light chain 10*ENSDARG0000006259252


Protein motifs (from Interpro)
Interpro ID Name
 IPR002048  EF-hand domain
 IPR011992  EF-hand domain pair
 IPR018247  EF-Hand 1, calcium-binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 molecular_functionGO:0005509 calcium ion binding IEA


Pathways (from Reactome)
Pathway description
Ephrin signaling
Smooth Muscle Contraction
RHO GTPases activate PAKs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000007723 efnb1 / ephrin-B1 / P52795* / P98172*  / reaction
 ENSDARG00000025319 fynb / F1RDG9 / FYN proto-oncogene, Src family tyrosine kinase b / FYN* / P39688* / P06241* / Tyrosine-protein kinase Fyn * / FYN proto-oncogene, Src family tyrosine kinase*  / reaction
 ENSDARG00000073848 arhgef7b / Rho guanine nucleotide exchange factor (GEF) 7b / Q14155* / ARHGEF7* / Rho guanine nucleotide exchange factor 7*  / reaction
 ENSDARG00000021539 ephb2b / eph receptor B2b / EPHB2* / P29323* / P54763* / EPH receptor B2* / Ephrin type-B receptor 2 *  / reaction
 ENSDARG00000020164 efnb2a / O73874 / ephrin-B2a / EFNB2* / P52799* / P52800* / ephrin B2*  / reaction
 ENSDARG00000042277 efnb3b / ephrin-B3b / EFNB3* / Q15768* / ephrin B3*  / reaction
 ENSDARG00000039489 git1 / G protein-coupled receptor kinase interacting ArfGAP 1 / Q68FF6* / Q9Y2X7* / GIT ArfGAP 1* / ARF GTPase-activating protein GIT1 *  / reaction
 ENSDARG00000043361 nck2b / NCK adaptor protein 2b / NCK2* / O43639* / O55033* / NCK adaptor protein 2* / Cytoplasmic protein NCK2 *  / reaction
 ENSDARG00000074050 efnb2b / ephrin-B2b / EFNB2* / P52800* / P52799* / ephrin B2*  / reaction
 ENSDARG00000018206 nck2a / NCK adaptor protein 2a / NCK2* / O43639* / O55033* / NCK adaptor protein 2* / Cytoplasmic protein NCK2 *  / reaction
 ENSDARG00000008107 src / Q1JPZ3 / v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog / P12931* / P05480* / Neuronal proto-onco tyrosine-protein kinase Src * / SRC proto-oncogene, non-receptor tyr...  / reaction
 ENSDARG00000006299 arhgef7a / Rho guanine nucleotide exchange factor (GEF) 7a / Q14155* / Q9ES28* / ARHGEF7* / Rho guanine nucleotide exchange factor 7*  / reaction
 ENSDARG00000076757 ephb1 / EPH receptor B1 / P54762* / Q8CBF3* / Ephrin type-B receptor 1 *  / reaction
 ENSDARG00000112993 efnb3a / ephrin-B3a / EFNB3* / Q15768* / O35393* / ephrin B3*  / reaction
 ENSDARG00000073732 myh14 / myosin, heavy chain 14, non-muscle / Q7Z406* / Q6URW6* / Myosin-14 * / myosin heavy chain 14*  / complex
 ENSDARG00000000103 myh10 / myosin, heavy chain 10, non-muscle / Q61879* / P35580* / Myosin-10 * / myosin heavy chain 10*  / complex
 ENSDARG00000025326 myl12.2 / myosin, light chain 12, genome duplicate 2 / Q3THE2* / MYL12A* / MYL12B* / O14950* / P19105* / myosin light chain 12A* / myosin light chain 12B* / Myosin regulatory light chain 12B *  / complex
 ENSDARG00000011370 fyna / Q6EWH2 / FYN proto-oncogene, Src family tyrosine kinase a / FYN* / P06241* / P39688* / Tyrosine-protein kinase Fyn * / FYN proto-oncogene, Src family tyrosine kinase*  / reaction
 ENSDARG00000037373 ephb2a / eph receptor B2a / EPHB2* / P29323* / P54763* / EPH receptor B2* / Ephrin type-B receptor 2 *  / reaction






 

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