ENSDARG00000000103


Danio rerio

Features
Gene ID: ENSDARG00000000103
  
Biological name :myh10
  
Synonyms : myh10 / myosin, heavy chain 10, non-muscle
  
Possible biological names infered from orthology : Myosin-10 / myosin heavy chain 10 / P35580 / Q61879
  
Species: Danio rerio
  
Chr. number: 6
Strand: 1
Band:
Gene start: 7553085
Gene end: 7658285
  
Corresponding Affymetrix probe sets: Dr.9142.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000148654
Ensembl peptide - ENSDARP00000125771
Ensembl peptide - ENSDARP00000125918
NCBI entrez gene - 555454     See in Manteia.
swissprot - F1R3G4
swissprot - I3ISA3
ZFIN ID - ZDB-GENE-030616-162
Ensembl - ENSDARG00000000103
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 MYH10ENSGALG00000001183Gallus gallus
 MYH10ENSG00000133026Homo sapiens
 Myh10ENSMUSG00000020900Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
myh11a / myosin, heavy chain 11a, smooth muscle / MYH11* / P35749* / myosin heavy chain 11*ENSDARG0000000978271
myh9a / myosin, heavy chain 9a, non-muscle / MYH9* / P35579* / Q8VDD5* / myosin heavy chain 9* / myosin, heavy polypeptide 9, non-muscle*ENSDARG0000006329571
myh9b / myosin, heavy chain 9b, non-muscle / MYH9* / P35579* / Q8VDD5* / myosin heavy chain 9* / myosin, heavy polypeptide 9, non-muscle*ENSDARG0000000101465
myh14 / myosin, heavy chain 14, non-muscle / Q7Z406* / Q6URW6* / Myosin-14 * / myosin heavy chain 14*ENSDARG0000007373265
myh11b / myosin, heavy chain 11b, smooth muscle / MYH11* / P35749* / myosin heavy chain 11*ENSDARG0000010097262
smyhc2 / slow myosin heavy chain 2 / MYH7* / MYH6* / P12883* / P13533* / myosin heavy chain 7* / myosin heavy chain 6*ENSDARG0000011403139
smyhc2 / slow myosin heavy chain 2 / MYH7* / MYH6* / P12883* / P13533* / myosin heavy chain 7* / myosin heavy chain 6*ENSDARG0000010396939
myh7l / myosin heavy chain 7-like / MYH6* / MYH7* / Q91Z83* / P12883* / P13533* / Q02566* / Myosin-7 * / myosin heavy chain 7* / myosin heavy chain 6* / myosin, heavy polypeptide 6, cardiac...ENSDARG0000007978239
CU633479.2 / MYH6* / MYH7* / P13533* / P12883* / myosin heavy chain 6* / myosin heavy chain 7*ENSDARG0000010383739
myh7 / myosin heavy chain 7 / MYH6* / Q91Z83* / P12883* / P13533* / Q02566* / Myosin-7 * / myosin heavy chain 6* / myosin, heavy polypeptide 6, cardiac muscle, alpha*ENSDARG0000007956439
myh7ba / myosin, heavy chain 7B, cardiac muscle, beta a / MYH7B* / A7E2Y1* / A2AQP0* / Myosin-7B * / myosin heavy chain 7B*ENSDARG0000007607538
smyhc1 / slow myosin heavy chain 1 / MYH7* / MYH6* / P12883* / P13533* / myosin heavy chain 7* / myosin heavy chain 6*ENSDARG0000009995938
myh7bb / myosin, heavy chain 7B, cardiac muscle, beta b / MYH7B* / A7E2Y1* / A2AQP0* / Myosin-7B * / myosin heavy chain 7B*ENSDARG0000003532238
myhb / myosin, heavy chain b / MYH2* / MYH4* / MYH8* / MYH1* / MYH13* / Q9Y623* / P12882* / P13535* / P13542* / Q5SX39* / Q5SX40* / Q9UKX2* / Q9UKX3* / Myosin-1 * / Myosin-8 * / Myosin-4 * ...ENSDARG0000000199338
myhz1.3 / myosin, heavy polypeptide 1.3, skeletal muscle / MYH2* / MYH4* / MYH8* / MYH1* / MYH13* / Q9Y623* / P12882* / P13535* / P13542* / Q5SX39* / Q5SX40* / Q9UKX2* / Q9UKX3* / Myosin-1 ...ENSDARG0000006799738
myhz2 / myosin, heavy polypeptide 2, fast muscle specific / MYH2* / MYH4* / MYH8* / MYH1* / MYH13* / Q9Y623* / P12882* / P13535* / P13542* / Q5SX39* / Q5SX40* / Q9UKX2* / Q9UKX3* / Myosin-1...ENSDARG0000001294438
myh6 / myosin, heavy chain 6, cardiac muscle, alpha / MYH7* / Q91Z83* / P12883* / P13533* / Q02566* / Myosin-7 * / myosin heavy chain 6* / myosin heavy chain 7* / myosin, heavy polypeptide ...ENSDARG0000009063737
myhz1.1 / myosin, heavy polypeptide 1.1, skeletal muscle / MYH2* / MYH4* / MYH8* / MYH1* / MYH13* / Q9Y623* / P12882* / P13535* / Q9UKX2* / Q9UKX3* / myosin heavy chain 1* / myosin heavy ch...ENSDARG0000010241431
CU633479.1 / MYH6* / MYH7* / P13533* / P12883* / myosin heavy chain 6* / myosin heavy chain 7*ENSDARG0000009874730
CABZ01079179.1 / MYH8* / MYH1* / MYH2* / MYH4* / MYH13* / Q9Y623* / P12882* / P13535* / Q9UKX2* / Q9UKX3* / myosin heavy chain 1* / myosin heavy chain 2* / myosin heavy chain 4* / myosin he...ENSDARG0000011059614


Protein motifs (from Interpro)
Interpro ID Name
 IPR000048  IQ motif, EF-hand binding site
 IPR001609  Myosin head, motor domain
 IPR002928  Myosin tail
 IPR004009  Myosin, N-terminal, SH3-like
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007018 microtubule-based movement IEA
 biological_processGO:0008360 regulation of cell shape IMP
 biological_processGO:0021555 midbrain-hindbrain boundary morphogenesis IMP
 biological_processGO:0070650 actin filament bundle distribution IMP
 cellular_componentGO:0016459 myosin complex IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003774 motor activity IEA
 molecular_functionGO:0003777 microtubule motor activity IEA
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008017 microtubule binding IEA
 molecular_functionGO:0051015 actin filament binding IEA


Pathways (from Reactome)
Pathway description
RHO GTPases activate PAKs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000042 midbrain hindbrain boundary midbrain hindbrain boundary basal side increased angle to brain epithelium, abnormal
midbrain hindbrain boundary cell decreased length , abnormal
midbrain hindbrain boundary cell increased width , abnormal
midbrain hindbrain boundary cell increased area , abnormal
Show

 ZFA:0000107 eye eye morphology , abnormal
Show

 ZFA:0000114 heart heart morphology , abnormal
Show

 ZFA:0000159 tectal ventricle tectal ventricle morphology , abnormal
Show

 ZFA:0001117 post-vent region post-vent region curved , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000025326 myl12.2 / myosin, light chain 12, genome duplicate 2 / Q3THE2* / MYL12A* / MYL12B* / O14950* / P19105* / myosin light chain 12A* / myosin light chain 12B* / Myosin regulatory light chain 12B *  / complex
 ENSDARG00000000103 myh10 / myosin, heavy chain 10, non-muscle / Q61879* / P35580* / Myosin-10 * / myosin heavy chain 10*  / complex
 ENSDARG00000073732 myh14 / myosin, heavy chain 14, non-muscle / Q7Z406* / Q6URW6* / Myosin-14 * / myosin heavy chain 14*  / complex






 

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