Manteia

ENSDARG00000012944

Danio rerio

Features

Gene ID:	ENSDARG00000012944

Biological name :	myhz2

Synonyms :	myhz2 / myosin, heavy polypeptide 2, fast muscle specific

Possible biological names infered from orthology :	MYH1 / MYH13 / MYH2 / MYH4 / MYH8 / Myosin-1 / Myosin-4 / Myosin-8 / myosin heavy chain 1 / myosin heavy chain 13 / myosin heavy chain 2 / myosin heavy chain 4 / myosin heavy chain 8 / P12882 / P13535 / P13542 / Q5SX39 / Q5SX40 / Q9UKX2 / Q9UKX3 / Q9Y623

Species:	Danio rerio

Chr. number:	5
Strand:	1
Band:
Gene start:	32206378
Gene end:	32217579

Corresponding Affymetrix probe sets:	Dr.4812.1.S1_s_at (Zebrafish Array) NM_152982_at (Zebrafish Genome Array with custom cdf files)

Cross references:	Ensembl peptide - ENSDARP00000051360 Ensembl peptide - ENSDARP00000108224 NCBI entrez gene - 246275 See in Manteia. RefSeq - XM_005171786 RefSeq - NM_152982 RefSeq Peptide - NP_694514 swissprot - Q6IQX1 ZFIN ID - ZDB-GENE-020604-1 Ensembl - ENSDARG00000012944

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Ortholog name	ID	Species
MYH13	ENSGALG00000029660	Gallus gallus
MYH1A	ENSGALG00000037864	Gallus gallus
MYH1B	ENSGALG00000039977	Gallus gallus
MYH1C	ENSGALG00000032404	Gallus gallus
MYH1D	ENSGALG00000027323	Gallus gallus
MYH1F	ENSGALG00000042257	Gallus gallus
MYH1G	ENSGALG00000028612	Gallus gallus
MYH1	ENSG00000109061	Homo sapiens
MYH13	ENSG00000006788	Homo sapiens
MYH2	ENSG00000125414	Homo sapiens
MYH4	ENSG00000264424	Homo sapiens
MYH8	ENSG00000133020	Homo sapiens
Myh1	ENSMUSG00000056328	Mus musculus
Myh13	ENSMUSG00000060180	Mus musculus
Myh2	ENSMUSG00000033196	Mus musculus
Myh4	ENSMUSG00000057003	Mus musculus
Myh8	ENSMUSG00000055775	Mus musculus

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
myhz1.3 / myosin, heavy polypeptide 1.3, skeletal muscle / MYH2* / MYH4* / MYH8* / MYH1* / MYH13* / Q9Y623* / P12882* / P13535* / P13542* / Q5SX39* / Q5SX40* / Q9UKX2* / Q9UKX3* / Myosin-1 ...	ENSDARG00000067997	98
myhb / myosin, heavy chain b / MYH2* / MYH4* / MYH8* / MYH1* / MYH13* / Q9Y623* / P12882* / P13535* / P13542* / Q5SX39* / Q5SX40* / Q9UKX2* / Q9UKX3* / Myosin-1 * / Myosin-8 * / Myosin-4 * ...	ENSDARG00000001993	89
smyhc1 / slow myosin heavy chain 1 / MYH7* / MYH6* / P12883* / P13533* / myosin heavy chain 7* / myosin heavy chain 6*	ENSDARG00000099959	79
myhz1.1 / myosin, heavy polypeptide 1.1, skeletal muscle / MYH2* / MYH4* / MYH8* / MYH1* / MYH13* / Q9Y623* / P12882* / P13535* / Q9UKX2* / Q9UKX3* / myosin heavy chain 1* / myosin heavy ch...	ENSDARG00000102414	78
smyhc2 / slow myosin heavy chain 2 / MYH7* / MYH6* / P12883* / P13533* / myosin heavy chain 7* / myosin heavy chain 6*	ENSDARG00000103969	78
myh7 / myosin heavy chain 7 / MYH6* / Q91Z83* / P12883* / P13533* / Q02566* / Myosin-7 * / myosin heavy chain 6* / myosin, heavy polypeptide 6, cardiac muscle, alpha*	ENSDARG00000079564	78
smyhc2 / slow myosin heavy chain 2 / MYH7* / MYH6* / P12883* / P13533* / myosin heavy chain 7* / myosin heavy chain 6*	ENSDARG00000114031	78
CU633479.2 / MYH6* / MYH7* / P13533* / P12883* / myosin heavy chain 6* / myosin heavy chain 7*	ENSDARG00000103837	77
myh7l / myosin heavy chain 7-like / MYH6* / MYH7* / Q91Z83* / P12883* / P13533* / Q02566* / Myosin-7 * / myosin heavy chain 7* / myosin heavy chain 6* / myosin, heavy polypeptide 6, cardiac...	ENSDARG00000079782	77
myh6 / myosin, heavy chain 6, cardiac muscle, alpha / MYH7* / Q91Z83* / P12883* / P13533* / Q02566* / Myosin-7 * / myosin heavy chain 6* / myosin heavy chain 7* / myosin, heavy polypeptide ...	ENSDARG00000090637	76
myh7ba / myosin, heavy chain 7B, cardiac muscle, beta a / MYH7B* / A7E2Y1* / A2AQP0* / Myosin-7B * / myosin heavy chain 7B*	ENSDARG00000076075	70
myh7bb / myosin, heavy chain 7B, cardiac muscle, beta b / MYH7B* / A7E2Y1* / A2AQP0* / Myosin-7B * / myosin heavy chain 7B*	ENSDARG00000035322	67
CU633479.1 / MYH6* / MYH7* / P13533* / P12883* / myosin heavy chain 6* / myosin heavy chain 7*	ENSDARG00000098747	57
myh9a / myosin, heavy chain 9a, non-muscle / MYH9* / P35579* / Q8VDD5* / myosin heavy chain 9* / myosin, heavy polypeptide 9, non-muscle*	ENSDARG00000063295	39
myh10 / myosin, heavy chain 10, non-muscle / Q61879* / P35580* / Myosin-10 * / myosin heavy chain 10*	ENSDARG00000000103	39
myh11a / myosin, heavy chain 11a, smooth muscle / MYH11* / P35749* / myosin heavy chain 11*	ENSDARG00000009782	39
myh14 / myosin, heavy chain 14, non-muscle / Q7Z406* / Q6URW6* / Myosin-14 * / myosin heavy chain 14*	ENSDARG00000073732	37
myh11b / myosin, heavy chain 11b, smooth muscle / MYH11* / P35749* / myosin heavy chain 11*	ENSDARG00000100972	37
myh9b / myosin, heavy chain 9b, non-muscle / MYH9* / P35579* / Q8VDD5* / myosin heavy chain 9* / myosin, heavy polypeptide 9, non-muscle*	ENSDARG00000001014	36
CABZ01079179.1 / MYH8* / MYH1* / MYH2* / MYH4* / MYH13* / Q9Y623* / P12882* / P13535* / Q9UKX2* / Q9UKX3* / myosin heavy chain 1* / myosin heavy chain 2* / myosin heavy chain 4* / myosin he...	ENSDARG00000110596	24

Protein motifs (from Interpro)

Interpro ID	Name
IPR000048	IQ motif, EF-hand binding site
IPR001609	Myosin head, motor domain
IPR002928	Myosin tail
IPR004009	Myosin, N-terminal, SH3-like
IPR027417	P-loop containing nucleoside triphosphate hydrolase

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0007018	microtubule-based movement	IEA
biological_process	GO:0014823	response to activity	IDA
biological_process	GO:0048741	skeletal muscle fiber development	IMP
cellular_component	GO:0016459	myosin complex	IEA
molecular_function	GO:0000166	nucleotide binding	IEA
molecular_function	GO:0003774	motor activity	IEA
molecular_function	GO:0003777	microtubule motor activity	IEA
molecular_function	GO:0003779	actin binding	IEA
molecular_function	GO:0005524	ATP binding	IEA
molecular_function	GO:0008017	microtubule binding	IEA
molecular_function	GO:0051015	actin filament binding	IEA

Pathways (from Reactome)

Pathway description

Regulation of actin dynamics for phagocytic cup formation

Striated Muscle Contraction

Phenotype (from MGI, Zfin or HPO)

ID	Phenotype	Definition	Genetic BG
ZFA:0000135	notochord	notochord deformed , abnormal	Show
ZFA:0000628	caudal fin musculature	caudal fin musculature sarcomere disorganized , abnormal	Show
ZFA:0001058	caudal fin	caudal fin muscle cell malformed , abnormal caudal fin muscle cell deformed , abnormal	Show
ZFA:0001094	whole organism	whole organism decreased length , abnormal	Show
ZFA:0009114	muscle cell	muscle cell malformed , abnormal muscle cell deformed , abnormal muscle cell sarcomere disorganized , abnormal	Show

Interacting proteins (from Reactome)

Interactor ID

Name

Interaction type

No match

0 s.

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		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr