ENSG00000264424


Homo sapiens

Features
Gene ID: ENSG00000264424
  
Biological name :MYH4
  
Synonyms : MYH4 / myosin heavy chain 4 / Q9Y623
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: -1
Band: p13.1
Gene start: 10443290
Gene end: 10469559
  
Corresponding Affymetrix probe sets: 208148_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000255381
NCBI entrez gene - 4622     See in Manteia.
OMIM - 160742
RefSeq - NM_017533
RefSeq - XM_017024676
RefSeq Peptide - NP_060003
swissprot - Q9Y623
Ensembl - ENSG00000264424
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CABZ01079179.1ENSDARG00000110596Danio rerio
 myhbENSDARG00000001993Danio rerio
 myhz1.1ENSDARG00000102414Danio rerio
 myhz1.3ENSDARG00000067997Danio rerio
 myhz2ENSDARG00000012944Danio rerio
 zgc:66156ENSDARG00000112287Danio rerio
 MYH1AENSGALG00000037864Gallus gallus
 MYH1BENSGALG00000039977Gallus gallus
 MYH1CENSGALG00000032404Gallus gallus
 MYH1DENSGALG00000027323Gallus gallus
 MYH1FENSGALG00000042257Gallus gallus
 MYH1GENSGALG00000028612Gallus gallus
 Myh4ENSMUSG00000057003Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MYH1 / P12882 / myosin heavy chain 1ENSG0000010906194
MYH2 / Q9UKX2 / myosin heavy chain 2ENSG0000012541492
MYH8 / P13535 / myosin heavy chain 8ENSG0000013302090
MYH3 / P11055 / myosin heavy chain 3ENSG0000010906383
MYH7 / P12883 / myosin heavy chain 7ENSG0000009205481
MYH13 / Q9UKX3 / myosin heavy chain 13ENSG0000000678881
MYH6 / P13533 / myosin heavy chain 6ENSG0000019761680
MYH7B / A7E2Y1 / myosin heavy chain 7BENSG0000007881467
MYH15 / Q9Y2K3 / myosin heavy chain 15ENSG0000014482160
MYH11 / P35749 / myosin heavy chain 11ENSG0000013339241
MYH10 / P35580 / myosin heavy chain 10ENSG0000013302640
MYH9 / P35579 / myosin heavy chain 9ENSG0000010034540
MYH14 / Q7Z406 / myosin heavy chain 14ENSG0000010535737


Protein motifs (from Interpro)
Interpro ID Name
 IPR000048  IQ motif, EF-hand binding site
 IPR001609  Myosin head, motor domain
 IPR002928  Myosin tail
 IPR004009  Myosin, N-terminal, SH3-like
 IPR008989  Myosin S1 fragment, N-terminal
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006936 muscle contraction IDA
 biological_processGO:0007018 microtubule-based movement IEA
 biological_processGO:0014823 response to activity IEA
 biological_processGO:0030048 actin filament-based movement NAS
 biological_processGO:0030049 muscle filament sliding NAS
 biological_processGO:0046034 ATP metabolic process NAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005859 muscle myosin complex NAS
 cellular_componentGO:0016459 myosin complex IEA
 cellular_componentGO:0030016 myofibril IDA
 cellular_componentGO:0030017 sarcomere NAS
 cellular_componentGO:0032982 myosin filament IEA
 molecular_functionGO:0000146 microfilament motor activity NAS
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003725 double-stranded RNA binding IDA
 molecular_functionGO:0003774 motor activity IEA
 molecular_functionGO:0003777 microtubule motor activity IEA
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0005516 calmodulin binding IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008017 microtubule binding IEA
 molecular_functionGO:0016887 ATPase activity NAS
 molecular_functionGO:0051015 actin filament binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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