ENSMUSG00000055775


Mus musculus

Features
Gene ID: ENSMUSG00000055775
  
Biological name :Myh8
  
Synonyms : Myh8 / Myosin-8 / P13542
  
Possible biological names infered from orthology : myosin heavy chain 8 / P13535
  
Species: Mus musculus
  
Chr. number: 11
Strand: 1
Band: B3
Gene start: 67277124
Gene end: 67308634
  
Corresponding Affymetrix probe sets: 10377148 (MoGene1.0st)   1426650_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000019625
Ensembl peptide - ENSMUSP00000104325
NCBI entrez gene - 17885     See in Manteia.
MGI - MGI:1339712
RefSeq - NM_177369
RefSeq Peptide - NP_796343
swissprot - P13542
swissprot - Q8BGE8
Ensembl - ENSMUSG00000055775
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CABZ01079179.1ENSDARG00000110596Danio rerio
 myhbENSDARG00000001993Danio rerio
 myhz1.1ENSDARG00000102414Danio rerio
 myhz1.3ENSDARG00000067997Danio rerio
 myhz2ENSDARG00000012944Danio rerio
 zgc:66156ENSDARG00000112287Danio rerio
 MYH1AENSGALG00000037864Gallus gallus
 MYH1BENSGALG00000039977Gallus gallus
 MYH1CENSGALG00000032404Gallus gallus
 MYH1DENSGALG00000027323Gallus gallus
 MYH1FENSGALG00000042257Gallus gallus
 MYH1GENSGALG00000028612Gallus gallus
 MYH8ENSG00000133020Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Myh2 / myosin heavy chain 2 / Q9UKX2*ENSMUSG0000003319694
Myh1 / Q5SX40 / Myosin-1 / P12882* / myosin heavy chain 1*ENSMUSG0000005632893
Myh4 / Q5SX39 / Myosin-4 / Q9Y623* / myosin heavy chain 4*ENSMUSG0000005700392
Myh3 / P13541 / Myosin-3 / P11055* / myosin heavy chain 3*ENSMUSG0000002090885
Myh13 / myosin heavy chain 13 / Q9UKX3*ENSMUSG0000006018083
Myh7 / Q91Z83 / Myosin-7 / P12883* / myosin heavy chain 7*ENSMUSG0000005309382
Myh6 / Q02566 / myosin, heavy polypeptide 6, cardiac muscle, alpha / P13533* / myosin heavy chain 6*ENSMUSG0000004075281
Myh7b / A2AQP0 / Myosin-7B / A7E2Y1* / myosin heavy chain 7B*ENSMUSG0000007465268
Myh15 / myosin heavy chain 15 / Q9Y2K3*ENSMUSG0000009200955
Myh11 / myosin heavy chain 11 / P35749*ENSMUSG0000001883041
Myh9 / Q8VDD5 / myosin, heavy polypeptide 9, non-muscle / P35579* / myosin heavy chain 9*ENSMUSG0000002244340
Myh10 / Q61879 / Myosin-10 / P35580* / myosin heavy chain 10*ENSMUSG0000002090040
Myh14 / Q6URW6 / Myosin-14 / Q7Z406* / myosin heavy chain 14*ENSMUSG0000003073937


Protein motifs (from Interpro)
Interpro ID Name
 IPR000048  IQ motif, EF-hand binding site
 IPR001609  Myosin head, motor domain
 IPR002928  Myosin tail
 IPR004009  Myosin, N-terminal, SH3-like
 IPR008989  Myosin S1 fragment, N-terminal
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0003009 skeletal muscle contraction IEA
 biological_processGO:0007018 microtubule-based movement IEA
 biological_processGO:0030049 muscle filament sliding IEA
 biological_processGO:0046034 ATP metabolic process IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0016459 myosin complex IEA
 cellular_componentGO:0030016 myofibril IEA
 cellular_componentGO:0032982 myosin filament IEA
 molecular_functionGO:0000146 microfilament motor activity IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003774 motor activity IEA
 molecular_functionGO:0003777 microtubule motor activity IEA
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008017 microtubule binding IEA
 molecular_functionGO:0016887 ATPase activity IEA
 molecular_functionGO:0051015 actin filament binding IEA


Pathways (from Reactome)
Pathway description
Striated Muscle Contraction


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000020908 Myh3 / P13541 / Myosin-3 / P11055* / myosin heavy chain 3*  / reaction / complex
 ENSMUSG00000051747 Ttn / titin / A2ASS6 / Q8WZ42*  / complex / reaction
 ENSMUSG00000038670 Mybpc2 / Q5XKE0 / Myosin-binding protein C, fast-type / Q14324*  / reaction / complex
 ENSMUSG00000055775 Myh8 / P13542 / Myosin-8 / P13535* / myosin heavy chain 8*  / complex / reaction
 ENSMUSG00000020061 Mybpc1 / myosin binding protein C, slow type / Q00872*  / complex / reaction
 ENSMUSG00000002100 Mybpc3 / myosin binding protein C, cardiac / Q14896*  / reaction / complex
 ENSMUSG00000040752 Myh6 / Q02566 / myosin, heavy polypeptide 6, cardiac muscle, alpha / P13533* / myosin heavy chain 6*  / complex / reaction
 ENSMUSG00000061086 Myl4 / Mus musculus myosin, light polypeptide 4 (Myl4), transcript variant 2, mRNA. / P12829* / myosin light chain 4*  / reaction / complex
 ENSMUSG00000059741 Myl3 / P09542 / Myosin light chain 3 / P08590*  / complex / reaction
 ENSMUSG00000013936 Myl2 / P51667 / Myosin regulatory light chain 2, ventricular/cardiac muscle isoform / P10916* / myosin light chain 2*  / reaction / complex
 ENSMUSG00000061816 Myl1 / P05977 / Myosin light chain 1/3, skeletal muscle isoform / P05976* / myosin light chain 1*  / reaction / complex






 

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