MP:0000266 | abnormal cardiac morphology | "anomalies in the hollow, muscular organ that maintains the circulation of the blood" [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
Show
Allelic Composition: Gata4tm1.2Wtp/Gata4tm1.2Wtp Genetic Background: involves: 129 * C57BL/6
|
MP:0000274 | enlarged heart | "increase over normal size of the heart" [J:29971] |
Show
Allelic Composition: MafOfl/MafOfl Genetic Background: either: 102/ElH or C3H/HeH
Allelic Composition: Mybpc3tm1.1Jse/Mybpc3tm1.1Jse Genetic Background: Not Specified
|
MP:0000278 | abnormal myocardial fiber morphology | "malformed or poorly developed cardiac muscle fibers, the multinucleated muscle cells of the heart" [J:18048] |
Show
Allelic Composition: MafOfl/MafOfl Genetic Background: either: 102/ElH or C3H/HeH
Allelic Composition: Mybpc3tm1.1Jse/Mybpc3tm1.1Jse Genetic Background: Not Specified
Allelic Composition: Mybpc3tm2.1Rmos/Mybpc3tm2.1Rmos,A1cfTg(Myh6-cre/Esr1*)1Jmk/0 Genetic Background: involves: 129 * C57BL/6 * FVB/N
|
MP:0001413 | abnormal response to new environment | "altered investigative behavior from controls in reactions associated with placing an animal in a new location" [CFG:Center for Functional Genomics , Northwestern University] |
Show
Allelic Composition: Hprttm1a(EUCOMM)Hmgu/Hprttm1a(EUCOMM)Hmgu Genetic Background: C57BL/6N-Hprttm1a(EUCOMM)Hmgu/Ieg
|
MP:0001625 | cardiac hypertrophy | "an increase in size of the cardiac tissue, not due to increased cell number " [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
Show
Allelic Composition: Mybpc3tm1Rmos/Mybpc3tm1Rmos Genetic Background: either: (involves: 129) or (involves: 129 * C57BL/6)
Allelic Composition: Mybpc3tm1Lcrr/Mybpc3tm1Lcrr Genetic Background: involves: 129S4/SvJae * Black Swiss
Allelic Composition: Mybpc3DBA/2J/Mybpc3DBA/2J,Myh7DBA/2J/Myh7DBA/2J Genetic Background: DBA/2J
|
MP:0002190 | disorganized myocardium | "malformed or poorly developed cardiac muscle layers" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:67044] |
Show
Allelic Composition: MafOfl/MafOfl Genetic Background: either: 102/ElH or C3H/HeH
Allelic Composition: Mybpc3tm1.1Jse/Mybpc3tm1.1Jse Genetic Background: Not Specified
Allelic Composition: Mybpc3tm1Rmos/Mybpc3tm1Rmos Genetic Background: either: (involves: 129) or (involves: 129 * C57BL/6)
|
MP:0002625 | left ventricle hypertrophy | "increased size of the left ventricle" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator] |
Show
Allelic Composition: MafOfl/MafOfl Genetic Background: either: 102/ElH or C3H/HeH
Allelic Composition: Mybpc3tm1.1Jse/Mybpc3tm1.1Jse Genetic Background: Not Specified
Allelic Composition: Mybpc3tm1Lcrr/Mybpc3tm1Lcrr Genetic Background: involves: 129S4/SvJae * Black Swiss
Allelic Composition: Mybpc3tm1Lcrr/Mybpc3+ Genetic Background: involves: 129S4/SvJae * Black Swiss
Allelic Composition: Mybpc3tm2.1Lcrr/Mybpc3tm2.1Lcrr Genetic Background: involves: 129S2/SvPasCrl * Black Swiss * C57BL/6 * CD-1 * DBA/2
|
MP:0002753 | dilated left ventricle | "an expansion in the volume of the lower left chamber of the heart" [J:82859, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator] |
Show
Allelic Composition: MafOfl/MafOfl Genetic Background: either: 102/ElH or C3H/HeH
Allelic Composition: Mybpc3tm1.1Jse/Mybpc3tm1.1Jse Genetic Background: Not Specified
Allelic Composition: Mybpc3tm1Rmos/Mybpc3tm1Rmos Genetic Background: either: (involves: 129) or (involves: 129 * C57BL/6)
Allelic Composition: Mybpc3tm1.1Jse/Mybpc3tm1.1Jse Genetic Background: involves: 129S/SvEv
Allelic Composition: Mybpc3tm1Rmos/Mybpc3tm1Rmos Genetic Background: involves: 129
|
MP:0002795 | dilated cardiomyopathy | "decreased function of the heart associated with cardiac enlargement and congestive heart failure" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
Show
Allelic Composition: MafOfl/MafOfl Genetic Background: either: 102/ElH or C3H/HeH
Allelic Composition: Mybpc3tm1.1Jse/Mybpc3tm1.1Jse Genetic Background: Not Specified
Allelic Composition: Mybpc3tm1.1Jse/Mybpc3tm1.1Jse Genetic Background: involves: 129S/SvEv
|
MP:0002833 | increased heart weight | "greater than average weight of the heart compared to the average for a particular strain" [RGD:Rat Genome Database submission] |
Show
Allelic Composition: MafOfl/MafOfl Genetic Background: either: 102/ElH or C3H/HeH
Allelic Composition: Mybpc3tm1.1Jse/Mybpc3tm1.1Jse Genetic Background: Not Specified
Allelic Composition: Mybpc3tm1.1Jse/Mybpc3tm1.1Jse Genetic Background: involves: 129S/SvEv
Allelic Composition: Mybpc3tm2.1Lcrr/Mybpc3tm2.1Lcrr Genetic Background: involves: 129S2/SvPasCrl * Black Swiss * C57BL/6 * CD-1 * DBA/2
Allelic Composition: Mybpc3DBA/2J/Mybpc3DBA/2J,Myh7DBA/2J/Myh7DBA/2J Genetic Background: DBA/2J
Allelic Composition: Mybpc3tm1a(EUCOMM)Hmgu/Mybpc3tm1a(EUCOMM)Hmgu Genetic Background: Not Specified
|
MP:0002837 | dystrophic cardiac calcinosis | "a condition characterized by the localized deposition of calcium salts in the heart; often occuring in association with inflammation or atherosclerotic lesions and other pathological states" [J:76777, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: MafOfl/MafOfl Genetic Background: either: 102/ElH or C3H/HeH
Allelic Composition: Mybpc3tm1.1Jse/Mybpc3tm1.1Jse Genetic Background: Not Specified
|
MP:0002953 | thick ventricular wall | "increased depth of the cardiac wall of the heart ventricles" [ava:Anna V. Anagnostopoulos , Mouse Genome Informatics Curator] |
Show
Allelic Composition: MafOfl/MafOfl Genetic Background: either: 102/ElH or C3H/HeH
Allelic Composition: Mybpc3tm1.1Jse/Mybpc3tm1.1Jse Genetic Background: Not Specified
Allelic Composition: Mybpc3DBA/2J/Mybpc3DBA/2J,Myh7DBA/2J/Myh7DBA/2J Genetic Background: DBA/2J
|
MP:0002972 | abnormal cardiac muscle contractility | "altered ability of the heart muscle to shorten or to develop increased tension, often measured by dP/dT max" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
Show
Allelic Composition: Mybpc3tm1Lcrr/Mybpc3tm1Lcrr Genetic Background: involves: 129S4/SvJae * Black Swiss
Allelic Composition: Mybpc3tm1.1Jse/Mybpc3tm1.1Jse Genetic Background: involves: 129S/SvEv
|
MP:0003019 | increased circulating chloride level | "elevated concentration of chlorine salts in the circulation" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, RGD:Rat Genome Database submission] |
Show
Allelic Composition: Mybpc3tm1a(EUCOMM)Hmgu/Mybpc3tm1a(EUCOMM)Hmgu Genetic Background: Not Specified
|
MP:0003141 | cardiac fibrosis | "formation of fibrous tissue within the heart often resulting from inflammation or injury " [smb:Susan M Bello, Mouse Genome Informatics Curator] |
Show
Allelic Composition: MafOfl/MafOfl Genetic Background: either: 102/ElH or C3H/HeH
Allelic Composition: Mybpc3tm1.1Jse/Mybpc3tm1.1Jse Genetic Background: Not Specified
Allelic Composition: Mybpc3tm2.1Rmos/Mybpc3tm2.1Rmos,A1cfTg(Myh6-cre/Esr1*)1Jmk/0 Genetic Background: involves: 129 * C57BL/6 * FVB/N
|
MP:0003157 | impaired muscle relaxation | "reduced or absent ability of muscle to lengthen following contractions" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:92510] |
Show
Allelic Composition: Mybpc3tm1Lcrr/Mybpc3tm1Lcrr Genetic Background: involves: 129S4/SvJae * Black Swiss
|
MP:0003921 | abnormal left ventricle morphology | "structural anomaly of the left lower chamber of the heart " [smb:Susan M Bello, Mouse Genome Informatics Curator] |
Show
Allelic Composition: MafOfl/MafOfl Genetic Background: either: 102/ElH or C3H/HeH
Allelic Composition: Mybpc3tm1.1Jse/Mybpc3tm1.1Jse Genetic Background: Not Specified
Allelic Composition: Mybpc3tm2.1Lcrr/Mybpc3tm2.1Lcrr Genetic Background: involves: 129S2/SvPasCrl * Black Swiss * C57BL/6 * CD-1 * DBA/2
Allelic Composition: Mybpc3tm2.1Rmos/Mybpc3tm2.1Rmos,A1cfTg(Myh6-cre/Esr1*)1Jmk/0 Genetic Background: involves: 129 * C57BL/6 * FVB/N
|
MP:0004058 | abnormal ventricular papillary muscle morphology | "structural anomaly of one of the group of myocardial bundles which terrminate in the chordae tendineae that attach to the cusps of the atrioventricular valves; each ventricle has an anterior and a posterior papillary muscle; the right ventricle sometimes has a septal papillary muscle" [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator] |
Show
Allelic Composition: MafOfl/MafOfl Genetic Background: either: 102/ElH or C3H/HeH
Allelic Composition: Mybpc3tm1.1Jse/Mybpc3tm1.1Jse Genetic Background: Not Specified
|
MP:0004063 | dilated left atrium | "an expansion in the volume of the left upper chamber of the heart" [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator] |
Show
Allelic Composition: MafOfl/MafOfl Genetic Background: either: 102/ElH or C3H/HeH
Allelic Composition: Mybpc3tm1.1Jse/Mybpc3tm1.1Jse Genetic Background: Not Specified
|
MP:0004084 | abnormal cardiac muscle relaxation | "altered ability of the cardiac/heart muscle to lengthen following contractions, often measured by dP/dt min" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator] |
Show
Allelic Composition: Mybpc3tm1.1Jse/Mybpc3tm1.1Jse Genetic Background: involves: 129S/SvEv
Allelic Composition: Mybpc3tm2.1Lcrr/Mybpc3tm2.1Lcrr Genetic Background: involves: 129S2/SvPasCrl * Black Swiss
Allelic Composition: Mybpc3tm2.1Lcrr/Mybpc3+ Genetic Background: involves: 129S2/SvPasCrl * Black Swiss
|
MP:0004094 | abnormal M lines | "any structural anomaly in the band in the center of the H band that contains proteins that crosslink the thick filament system (myosins) and the M-band part of the elastic filaments" [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator] |
Show
Allelic Composition: MafOfl/MafOfl Genetic Background: either: 102/ElH or C3H/HeH
Allelic Composition: Mybpc3tm1.1Jse/Mybpc3tm1.1Jse Genetic Background: Not Specified
|
MP:0004215 | abnormal myocardial fiber physiology | "anomaly in the function of the multinucleated muscle cells of the heart" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Mybpc3tm1Rmos/Mybpc3tm1Rmos Genetic Background: either: (involves: 129) or (involves: 129 * C57BL/6)
Allelic Composition: Mybpc3tm2.1Lcrr/Mybpc3tm2.1Lcrr Genetic Background: involves: 129S2/SvPasCrl * Black Swiss
Allelic Composition: Mybpc3tm2.1Lcrr/Mybpc3+ Genetic Background: involves: 129S2/SvPasCrl * Black Swiss
|
MP:0004485 | increased response of heart to induced stress | "increase in severity of the physiological response of the heart to induced stress such as cardiac hypertrophy due to mechanical pressure overload from aortic banding" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Mybpc3tm2.1Rmos/Mybpc3tm2.1Rmos,A1cfTg(Myh6-cre/Esr1*)1Jmk/0 Genetic Background: involves: 129 * C57BL/6 * FVB/N
Allelic Composition: Mybpc3tm1Rmos/Mybpc3tm1Rmos Genetic Background: involves: 129
|
MP:0004564 | enlarged myocardial fiber | "increased size of cardiac muscle fibers, the multinucleated muscle cells of the heart" [MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Mybpc3tm2.1Lcrr/Mybpc3tm2.1Lcrr Genetic Background: involves: 129S2/SvPasCrl * Black Swiss * C57BL/6 * CD-1 * DBA/2
Allelic Composition: Mybpc3tm2.1Lcrr/Mybpc3+ Genetic Background: involves: 129S2/SvPasCrl * Black Swiss * C57BL/6 * CD-1 * DBA/2
Allelic Composition: Mybpc3tm2.1Rmos/Mybpc3tm2.1Rmos,A1cfTg(Myh6-cre/Esr1*)1Jmk/0 Genetic Background: involves: 129 * C57BL/6 * FVB/N
Allelic Composition: Mybpc3DBA/2J/Mybpc3DBA/2J,Myh7DBA/2J/Myh7DBA/2J Genetic Background: DBA/2J
|
MP:0005140 | decreased cardiac muscle contractility | "inability or reduced ability of the heart muscle to shorten or to develop increased tension" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: Mybpc3tm1Rmos/Mybpc3tm1Rmos Genetic Background: either: (involves: 129) or (involves: 129 * C57BL/6)
Allelic Composition: Mybpc3tm1Lcrr/Mybpc3tm1Lcrr Genetic Background: involves: 129S4/SvJae * Black Swiss
Allelic Composition: Mybpc3tm2.1Lcrr/Mybpc3tm2.1Lcrr Genetic Background: involves: 129S2/SvPasCrl * Black Swiss * C57BL/6 * CD-1 * DBA/2
|
MP:0005330 | cardiomyopathy | "diseases of the heart (myocardium); may result from many causes" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, J:80681] |
Show
Allelic Composition: Mybpc3tm1Rmos/Mybpc3tm1Rmos Genetic Background: either: (involves: 129) or (involves: 129 * C57BL/6)
|
MP:0005598 | decreased ventricle muscle contractility | "reduced ability of the heart ventricle muscle to shorten or to develop increased tension" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, RGD:Rat Genome Database submission] |
Show
Allelic Composition: MafOfl/MafOfl Genetic Background: either: 102/ElH or C3H/HeH
Allelic Composition: Mybpc3tm1.1Jse/Mybpc3tm1.1Jse Genetic Background: Not Specified
Allelic Composition: Mybpc3tm1Rmos/Mybpc3tm1Rmos Genetic Background: either: (involves: 129) or (involves: 129 * C57BL/6)
Allelic Composition: Mybpc3tm2.1Rmos/Mybpc3tm2.1Rmos,A1cfTg(Myh6-cre/Esr1*)1Jmk/0 Genetic Background: involves: 129 * C57BL/6 * FVB/N
Allelic Composition: Mybpc3tm1Rmos/Mybpc3tm1Rmos Genetic Background: involves: 129
|
MP:0005599 | increased cardiac muscle contractility | "greater than the normal ability of the heart muscle to shorten or to develop increased tension
" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, RGD:Rat Genome Database submission] |
Show
Allelic Composition: Mybpc3tm1.1Jse/Mybpc3tm1.1Jse Genetic Background: involves: 129S/SvEv
|
MP:0005608 | cardiac interstitial fibrosis | "formation of fibrous tissue within the interstices of the heart as a result of repair or a reactive process" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, RGD:Rat Genome Database submission] |
Show
Allelic Composition: MafOfl/MafOfl Genetic Background: either: 102/ElH or C3H/HeH
Allelic Composition: Mybpc3tm1.1Jse/Mybpc3tm1.1Jse Genetic Background: Not Specified
Allelic Composition: Mybpc3tm1Rmos/Mybpc3tm1Rmos Genetic Background: either: (involves: 129) or (involves: 129 * C57BL/6)
Allelic Composition: Mybpc3tm1Lcrr/Mybpc3tm1Lcrr Genetic Background: involves: 129S4/SvJae * Black Swiss
Allelic Composition: Mybpc3tm2.1Lcrr/Mybpc3tm2.1Lcrr Genetic Background: involves: 129S2/SvPasCrl * Black Swiss * C57BL/6 * CD-1 * DBA/2
Allelic Composition: Mybpc3tm2.1Rmos/Mybpc3tm2.1Rmos,A1cfTg(Myh6-cre/Esr1*)1Jmk/0 Genetic Background: involves: 129 * C57BL/6 * FVB/N
Allelic Composition: Mybpc3DBA/2J/Mybpc3DBA/2J,Myh7DBA/2J/Myh7DBA/2J Genetic Background: DBA/2J
|
MP:0008805 | decreased circulating amylase level | "reduction in the concentration of a group of amylolytic enzymes that cleave starch, glycogen, and related alpha-1,4-glucans in the blood" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MESH:D08.811.277.450.066, MGI:brs "Beverly Richards-Smith, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Mybpc3tm1a(EUCOMM)Hmgu/Mybpc3tm1a(EUCOMM)Hmgu Genetic Background: Not Specified
|
MP:0011925 | abnormal heart echocardiography feature | "any anomaly in echocardiographic representation of systolic and diastolic function, ventricular compliance, valvular function, or interventricular septum features" [MPD:Molly] |
Show
Allelic Composition: Mybpc3DBA/2J/Mybpc3DBA/2J,Myh7DBA/2J/Myh7DBA/2J Genetic Background: DBA/2J
Allelic Composition: Mybpc3tm2.1Lcrr/Mybpc3tm2.1Lcrr Genetic Background: involves: 129S2/SvPasCrl * Black Swiss
|
MP:0011952 | decreased cardiac stroke volume | "reduction in the volume of blood pushed into the aorta with each beat of the heart" [MGI:csmith] |
Show
Allelic Composition: Mybpc3tm1.1Jse/Mybpc3tm1.1Jse Genetic Background: involves: 129S/SvEv
|