ENSMUSG00000020061


Mus musculus

Features
Gene ID: ENSMUSG00000020061
  
Biological name :Mybpc1
  
Synonyms : Mybpc1 / myosin binding protein C, slow type
  
Possible biological names infered from orthology : Q00872
  
Species: Mus musculus
  
Chr. number: 10
Strand: -1
Band: C1
Gene start: 88518279
Gene end: 88605152
  
Corresponding Affymetrix probe sets: 10371627 (MoGene1.0st)   1442769_at (Mouse Genome 430 2.0 Array)   1444341_at (Mouse Genome 430 2.0 Array)   1455645_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000112615
Ensembl peptide - ENSMUSP00000112699
Ensembl peptide - ENSMUSP00000119024
Ensembl peptide - ENSMUSP00000122472
NCBI entrez gene - 109272     See in Manteia.
MGI - MGI:1336213
RefSeq - XM_006513058
RefSeq - XM_006513052
RefSeq - XM_006513053
RefSeq - XM_006513054
RefSeq - XM_006513055
RefSeq - XM_006513056
RefSeq - XM_006513057
RefSeq - NM_001252372
RefSeq - NM_175418
RefSeq - XM_006513045
RefSeq - XM_006513046
RefSeq - XM_006513047
RefSeq - XM_006513048
RefSeq - XM_006513049
RefSeq - XM_006513050
RefSeq - XM_006513051
RefSeq Peptide - NP_001239301
RefSeq Peptide - NP_780627
swissprot - F7D574
swissprot - F6RQD1
swissprot - Q6P6L5
swissprot - D3YU50
Ensembl - ENSMUSG00000020061
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mybpc1ENSDARG00000045560Danio rerio
 MYBPC1ENSGALG00000012783Gallus gallus
 MYBPC1ENSG00000196091Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Mybpc2 / Q5XKE0 / Myosin-binding protein C, fast-type / Q14324*ENSMUSG0000003867050
Mybpc3 / myosin binding protein C, cardiac / Q14896*ENSMUSG0000000210050
Igfn1 / Q3KNY0 / Immunoglobulin-like and fibronectin type III domain-containing protein 1 / Q86VF2* / immunoglobulin-like and fibronectin type III domain containing 1*ENSMUSG0000005198525
Mybph / P70402 / Mus musculus myosin binding protein H (Mybph), transcript variant 2, mRNA. / Q13203* / myosin binding protein H*ENSMUSG0000004245121
Myom1 / Q62234 / Myomesin-1 / P52179*ENSMUSG0000002404918
Myom3 / A2ABU4 / Myomesin-3 / Q5VTT5*ENSMUSG0000003713917
Myom2 / myomesin 2 / P54296*ENSMUSG0000003146117
Mybphl / Q5FW53 / Myosin-binding protein H-like / A2RUH7*ENSMUSG0000006874515


Protein motifs (from Interpro)
Interpro ID Name
 IPR003598  Immunoglobulin subtype 2
 IPR003599  Immunoglobulin subtype
 IPR003961  Fibronectin type III
 IPR007110  Immunoglobulin-like domain
 IPR013098  Immunoglobulin I-set
 IPR013783  Immunoglobulin-like fold
 IPR036116  Fibronectin type III superfamily
 IPR036179  Immunoglobulin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006936 muscle contraction IDA
 biological_processGO:0006941 striated muscle contraction IBA
 biological_processGO:0007010 cytoskeleton organization IEA
 biological_processGO:0007015 actin filament organization IBA
 biological_processGO:0045214 sarcomere organization IBA
 biological_processGO:0071688 striated muscle myosin thick filament assembly IBA
 biological_processGO:1903955 positive regulation of protein targeting to mitochondrion ISO
 cellular_componentGO:0005856 cytoskeleton TAS
 cellular_componentGO:0005859 muscle myosin complex IBA
 cellular_componentGO:0030018 Z disc IBA
 cellular_componentGO:0031430 M band IBA
 molecular_functionGO:0005200 structural constituent of cytoskeleton TAS
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0008307 structural constituent of muscle IBA
 molecular_functionGO:0051015 actin filament binding IBA
 molecular_functionGO:0051371 muscle alpha-actinin binding IBA
 molecular_functionGO:0097493 structural molecule activity conferring elasticity IBA


Pathways (from Reactome)
Pathway description
Striated Muscle Contraction


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000020908 Myh3 / P13541 / Myosin-3 / P11055* / myosin heavy chain 3*  / complex / reaction
 ENSMUSG00000051747 Ttn / titin / A2ASS6 / Q8WZ42*  / complex
 ENSMUSG00000061086 Myl4 / Mus musculus myosin, light polypeptide 4 (Myl4), transcript variant 2, mRNA. / P12829* / myosin light chain 4*  / complex
 ENSMUSG00000013936 Myl2 / P51667 / Myosin regulatory light chain 2, ventricular/cardiac muscle isoform / P10916* / myosin light chain 2*  / complex
 ENSMUSG00000055775 Myh8 / P13542 / Myosin-8 / P13535* / myosin heavy chain 8*  / complex / reaction
 ENSMUSG00000061816 Myl1 / P05977 / Myosin light chain 1/3, skeletal muscle isoform / P05976* / myosin light chain 1*  / complex
 ENSMUSG00000040752 Myh6 / Q02566 / myosin, heavy polypeptide 6, cardiac muscle, alpha / P13533* / myosin heavy chain 6*  / reaction / complex
 ENSMUSG00000059741 Myl3 / P09542 / Myosin light chain 3 / P08590*  / complex






 

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