Manteia

ID	Phenotype	Definition	Genetic BG
MP:0000228	abnormal thrombopoiesis	"abnormal development of the non-nucleated cells of the blood (platelets, thrombocytes) involved in blood coagulation" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]	Show Allelic Composition: Ttn^tm1.1Hgra/Ttn^tm1.1Hgra Genetic Background: involves: 129S6/SvEvTac * C57BL/6J
MP:0000229	abnormal megakaryocyte differentiation	"atypical process of formation and development these very large bone marrow cells which release mature platelets" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]	Show Allelic Composition: Ttn^tm1.1Hgra/Ttn^tm1.1Hgra Genetic Background: involves: 129S6/SvEvTac * C57BL/6J
MP:0000358	abnormal cell content/ morphology	"structural anomalies of the minute protoplasmic masses that make up organized tissues and which are the fundamental structural and functional units of living organisms" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003]	Show Allelic Composition: Slc26a4^loop/Slc26a4^loop Genetic Background: involves: C3HeB/FeJ Allelic Composition: Myh9^{tm3(GFP/MYH9/MYH10)Rsad}/Myh9^{tm3(GFP/MYH9/MYH10)Rsad} Genetic Background: involves: 129S4/SvJae * C57BL/6 Allelic Composition: Myh9^{tm4(GFP/MYH10/MYH9)Rsad}/Myh9^{tm4(GFP/MYH10/MYH9)Rsad} Genetic Background: involves: 129S4/SvJae * C57BL/6
MP:0001304	cataracts	"complete or partial opacity of the lens" [J:65031]	Show Allelic Composition: Kdm6a^tm1.2Afst/Kdm6a^tm1.2Afst Genetic Background: involves: 129S1/Sv * 129X1/SvJ * BALB/c * C57BL/6 Allelic Composition: Myh9^tm7.1Rsad/Myh9⁺ Genetic Background: involves: BALB/cJ Allelic Composition: Myh9^tm7.1Rsad/Myh9^tm7.1Rsad Genetic Background: involves: BALB/cJ
MP:0001313	increased incidence of corneal inflammation	"greater than average and persistent occurrence of corneal irritation" [J:4606]	Show Allelic Composition: Kdm6a^tm1.2Afst/Kdm6a^tm1.2Afst Genetic Background: involves: 129S1/Sv * 129X1/SvJ * BALB/c * C57BL/6
MP:0001674	abnormal triploblastic development	"abnormal development of the three primary germ layers" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, tc:Teresa Chu , Mouse Genome Informatics Curator]	Show Allelic Composition: Dll4^tm1Nwg/Dll4⁺ Genetic Background: involves: 129S6/SvEvTac * C57BL/6NTac * ICR
MP:0001696	failure to gastrulate	"inability to differentiate and invaginate the primary germ layers" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:cls, J:34458]	Show Allelic Composition: Dll4^tm1Nwg/Dll4⁺ Genetic Background: involves: 129S6/SvEvTac * C57BL/6NTac * ICR
MP:0001698	reduced embryo size	"smaller proportions of embryo compared to littermates" [J:61790]	Show Allelic Composition: Myh9^{tm6.1(EGFP/MYH9)Rsad}/Myh9⁺ Genetic Background:* involves: 129S4/SvJae * BALB/cJ * C57BL/6
MP:0001711	abnormal placenta		Show Allelic Composition: Slc26a4^loop/Slc26a4^loop Genetic Background: involves: C3HeB/FeJ Allelic Composition: Myh9^{tm4(GFP/MYH10/MYH9)Rsad}/Myh9^{tm4(GFP/MYH10/MYH9)Rsad} Genetic Background: involves: 129S4/SvJae * C57BL/6
MP:0001716	abnormal placental labyrinth	"malformed structure where embryonic blood vessels are surrounded by trophoblast cells and maternal blood" [J:23171]	Show Allelic Composition: Slc26a4^loop/Slc26a4^loop Genetic Background: involves: C3HeB/FeJ Allelic Composition: Myh9^{tm4(GFP/MYH10/MYH9)Rsad}/Myh9^{tm4(GFP/MYH10/MYH9)Rsad} Genetic Background: involves: 129S4/SvJae * C57BL/6
MP:0001722	pale yolk sac	"bloodless yolk sac" [J:62571]	Show Allelic Composition: Slc26a4^loop/Slc26a4^loop Genetic Background: involves: C3HeB/FeJ Allelic Composition: Myh9^{tm3(GFP/MYH9/MYH10)Rsad}/Myh9^{tm3(GFP/MYH9/MYH10)Rsad} Genetic Background: involves: 129S4/SvJae * C57BL/6 Allelic Composition: Myh9^{tm4(GFP/MYH10/MYH9)Rsad}/Myh9^{tm4(GFP/MYH10/MYH9)Rsad} Genetic Background: involves: 129S4/SvJae * C57BL/6
MP:0002169	no phenotype detected	"normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Clock^tm1.1Rep/Clock^tm1.1Rep Genetic Background: involves: 129S4/SvJae * C57BL/6J Allelic Composition: Myh9^{tm1(mCherry/MYH9)Rsad}/Myh9^{tm1(mCherry/MYH9)Rsad} Genetic Background: involves: 129S4/SvJae * C57BL/6
MP:0002417	abnormal megakaryocyte morphology/development	"anomalous structure or formation of the very large cells found in the bone marrow that release platelets" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Myh9^{tm1.1(MYH9)Mjk}/Myh9⁺ Genetic Background:* B6.Cg-Myh9^{tm1.1(MYH9)Mjk} Allelic Composition:* Myh9^tm7.1Rsad/Myh9^tm7.1Rsad Genetic Background: involves: BALB/cJ
MP:0002444	abnormal T cell physiology	"anomalous response of T lymphocytes" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Akt2^tm1.1Mbb/Akt2^tm1.1Mbb,Pten^tm1Hwu/Pten^tm1Hwu,Speer6-ps1^{Tg(Alb-cre)21Mgn}/Speer6-ps1⁺ Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * DBA Allelic Composition: Myh9^tm5Rsad/Myh9^tm5Rsad,Tg(Lck-cre)#Nik/0 Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J * DBA/2
MP:0002551	abnormal blood coagulation	"altered ability or inability of the blood to clot" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Map3k5^tm1Hijo/Map3k5^tm1Hijo,Map3k6^tm1Hijo/Map3k6^tm1Hijo Genetic Background: B6.129-Map3k6^tm1Hijo Map3k5^tm1Hijo Allelic Composition: Myh9^{tm6.1(EGFP/MYH9)Rsad}/Myh9⁺ Genetic Background:* involves: 129S4/SvJae * BALB/cJ * C57BL/6
MP:0002840	abnormal lens fibers morphology	"structural anomaly of the elongated cells of the crystalline lens of the eye" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]	Show Allelic Composition: Kdm6a^tm1.2Afst/Kdm6a^tm1.2Afst Genetic Background: involves: 129S1/Sv * 129X1/SvJ * BALB/c * C57BL/6 Allelic Composition: Myh9^tm1.1Dash/Myh9⁺ Genetic Background: involves: 129S2/SvPas * C57BL/6 * C57BL/6J * CBA
MP:0002871	albuminuria	"presence of excess albumin in the urine" [RGD:Rat Genome Database submission, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]	Show Allelic Composition: Vhl^tm1Jae/Vhl^tm1Jae,Tg(NPHS2-cre)295Lbh/? Genetic Background: involves: 129S4/SvJae * C57BL/6 * SJL Allelic Composition: Myh9^{tm1.1(MYH9)Mjk}/Myh9⁺ Genetic Background:* B6.Cg-Myh9^{tm1.1(MYH9)Mjk} Allelic Composition:* Myh9^{tm1.1(MYH9)Mjk}/Myh9^{tm1.1(MYH9)Mjk} Genetic Background: B6.129-Myh9^{tm1.1(MYH9)Mjk} Allelic Composition:* Myh9^tm7.1Rsad/Myh9⁺ Genetic Background: involves: BALB/cJ Allelic Composition: Myh9^tm7.1Rsad/Myh9^tm7.1Rsad Genetic Background: involves: BALB/cJ Allelic Composition: Myh9^tm5Rsad/Myh9^tm5Rsad,Tg(Nphs2-cre)1Seq/0 Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ Allelic Composition: Myh9^tm1.1Dash/Myh9⁺ Genetic Background: involves: 129S2/SvPas * C57BL/6 * C57BL/6J * CBA
MP:0003091	abnormal cell migration	"defect in the movement of cells during developmental processes" [smb:Susan M. Bello, Mouse Genome Informatics Curator]	Show Allelic Composition: Slc26a4^loop/Slc26a4^loop Genetic Background: involves: C3HeB/FeJ Allelic Composition: Myh9^{tm3(GFP/MYH9/MYH10)Rsad}/Myh9^{tm3(GFP/MYH9/MYH10)Rsad} Genetic Background: involves: 129S4/SvJae * C57BL/6 Allelic Composition: Myh9^{tm4(GFP/MYH10/MYH9)Rsad}/Myh9^{tm4(GFP/MYH10/MYH9)Rsad} Genetic Background: involves: 129S4/SvJae * C57BL/6
MP:0003156	abnormal lymphocyte migration/homing	"altered ability of blood lymphocytes to bind to high endothelial venules (HEV), tether and roll along the luminal aspects of HEV, and migrate into the lymph nodes" [acv:Alicia C. Valenzuela, Mouse Genome Informatics Curator, J:92231]	Show Allelic Composition: Akt2^tm1.1Mbb/Akt2^tm1.1Mbb,Pten^tm1Hwu/Pten^tm1Hwu,Speer6-ps1^{Tg(Alb-cre)21Mgn}/Speer6-ps1⁺ Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * DBA Allelic Composition: Myh9^tm5Rsad/Myh9^tm5Rsad,Tg(Lck-cre)#Nik/0 Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J * DBA/2
MP:0003179	decreased platelet count	"fewer than the normal numbers of the non-nucleated cells found in the blood and involved in blood coagulation " [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, hdene:Howard Dene , Mouse Genome Informatics Curator, J:93052]	Show Allelic Composition: Map3k5^tm1Hijo/Map3k5^tm1Hijo,Map3k6^tm1Hijo/Map3k6^tm1Hijo Genetic Background: B6.129-Map3k6^tm1Hijo Map3k5^tm1Hijo Allelic Composition: Myh9^{tm1.1(MYH9)Mjk}/Myh9⁺ Genetic Background:* B6.Cg-Myh9^{tm1.1(MYH9)Mjk} Allelic Composition:* Myh9^{tm1.1(MYH9)Mjk}/Myh9^{tm1.1(MYH9)Mjk} Genetic Background: B6.129-Myh9^{tm1.1(MYH9)Mjk} Allelic Composition:* Myh9^tm7.1Rsad/Myh9⁺ Genetic Background: involves: BALB/cJ Allelic Composition: Myh9^tm7.1Rsad/Myh9^tm7.1Rsad Genetic Background: involves: BALB/cJ Allelic Composition: Myh9^{tm6.1(EGFP/MYH9)Rsad}/Myh9⁺ Genetic Background:* involves: 129S4/SvJae * BALB/cJ * C57BL/6 Allelic Composition: Myh9^tm1.1Dash/Myh9⁺ Genetic Background: involves: 129S2/SvPas * C57BL/6 * C57BL/6J * CBA
MP:0003227	abnormal vascular branching morphogenesis	"increase, decrease or anomaly in the process by which new vessels sprout off pre-existing vessels" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:93157]	Show Allelic Composition: Slc26a4^loop/Slc26a4^loop Genetic Background: involves: C3HeB/FeJ
MP:0003229	abnormal vitelline vasculature	"malformation in the vessels of the yolk sac" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:93257]	Show Allelic Composition: Slc26a4^loop/Slc26a4^loop Genetic Background: involves: C3HeB/FeJ Allelic Composition: Myh9^{tm3(GFP/MYH9/MYH10)Rsad}/Myh9^{tm3(GFP/MYH9/MYH10)Rsad} Genetic Background: involves: 129S4/SvJae * C57BL/6 Allelic Composition: Myh9^{tm4(GFP/MYH10/MYH9)Rsad}/Myh9^{tm4(GFP/MYH10/MYH9)Rsad} Genetic Background: involves: 129S4/SvJae * C57BL/6
MP:0003405	abnormal platelet shape		Show Allelic Composition: Map3k5^tm1Hijo/Map3k5^tm1Hijo,Map3k6^tm1Hijo/Map3k6^tm1Hijo Genetic Background: B6.129-Map3k6^tm1Hijo Map3k5^tm1Hijo
MP:0003566	abnormal cell adhesion	"altered ability of a cell to adhere to another cell or to a non-cellular component of the environment" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator]	Show Allelic Composition: Slc26a4^loop/Slc26a4^loop Genetic Background: involves: C3HeB/FeJ Allelic Composition: Myh9^{tm3(GFP/MYH9/MYH10)Rsad}/Myh9^{tm3(GFP/MYH9/MYH10)Rsad} Genetic Background: involves: 129S4/SvJae * C57BL/6 Allelic Composition: Myh9^{tm4(GFP/MYH10/MYH9)Rsad}/Myh9^{tm4(GFP/MYH10/MYH9)Rsad} Genetic Background: involves: 129S4/SvJae * C57BL/6
MP:0003628	abnormal lymphocyte adhesion	"anomaly in the number of or process by which lymphocytes adhere to the luminal aspects of high endothelial venules prior to transmigration out of the vessel" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:95656]	Show Allelic Composition: Myh9^tm5Rsad/Myh9^tm5Rsad,Tg(Lck-cre)#Nik/0 Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J * DBA/2
MP:0003984	embryonic growth retardation	"slow or limited development before birth" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Slc26a4^loop/Slc26a4^loop Genetic Background: involves: C3HeB/FeJ Allelic Composition: Myh9^{tm6.1(EGFP/MYH9)Rsad}/Myh9^{tm6.1(EGFP/MYH9)Rsad} Genetic Background: involves: 129S4/SvJae * BALB/cJ * C57BL/6
MP:0004255	abnormal spongiotrophoblast layer morphology	"anomaly in the structure of the outer structural layer of the rodent placenta" [PMID:11433360]	Show Allelic Composition: Slc26a4^loop/Slc26a4^loop Genetic Background: involves: C3HeB/FeJ Allelic Composition: Myh9^{tm4(GFP/MYH10/MYH9)Rsad}/Myh9^{tm4(GFP/MYH10/MYH9)Rsad} Genetic Background: involves: 129S4/SvJae * C57BL/6
MP:0004258	abnormal placenta size	"anomaly in the size or shape of the organ of metabolic interchange between fetus and mother" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Slc26a4^loop/Slc26a4^loop Genetic Background: involves: C3HeB/FeJ Allelic Composition: Myh9^{tm4(GFP/MYH10/MYH9)Rsad}/Myh9^{tm4(GFP/MYH10/MYH9)Rsad} Genetic Background: involves: 129S4/SvJae * C57BL/6
MP:0004392	abnormal CD8-positive T cell physiology	"abnormal function of the subset of T lymphocytes that express the CD8 marker on the cell surface" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Myh9^tm5Rsad/Myh9^tm5Rsad,Tg(Lck-cre)#Nik/0 Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J * DBA/2
MP:0004720	abnormal platelet morphology	"any structural anomaly of blood plasma cells derived from megakaryocytes, which function to promote blood clotting" [MESH:National Library of Medicine_Medical Subject Headings]	Show Allelic Composition: Map3k5^tm1Hijo/Map3k5^tm1Hijo,Map3k6^tm1Hijo/Map3k6^tm1Hijo Genetic Background: B6.129-Map3k6^tm1Hijo Map3k5^tm1Hijo Allelic Composition: Myh9^{tm1.1(MYH9)Mjk}/Myh9⁺ Genetic Background:* B6.Cg-Myh9^{tm1.1(MYH9)Mjk} Allelic Composition:* Myh9^{tm1.1(MYH9)Mjk}/Myh9^{tm1.1(MYH9)Mjk} Genetic Background: B6.129-Myh9^{tm1.1(MYH9)Mjk} Allelic Composition:* Myh9^tm7.1Rsad/Myh9⁺ Genetic Background: involves: BALB/cJ Allelic Composition: Myh9^tm7.1Rsad/Myh9^tm7.1Rsad Genetic Background: involves: BALB/cJ Allelic Composition: Myh9^{tm6.1(EGFP/MYH9)Rsad}/Myh9⁺ Genetic Background:* involves: 129S4/SvJae * BALB/cJ * C57BL/6 Allelic Composition: Myh9^tm1.1Dash/Myh9⁺ Genetic Background: involves: 129S2/SvPas * C57BL/6 * C57BL/6J * CBA
MP:0004748	increased susceptibility to age-related hearing loss	"greater than normal loss of hearing associated with advancing age, manifest as reduced ability to perceive or discriminate sounds; the pattern and age of onset vary" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]	Show Allelic Composition: Myh9^{tm1.1(MYH9)Mjk}/Myh9⁺ Genetic Background:* B6.Cg-Myh9^{tm1.1(MYH9*)Mjk}
MP:0004950	abnormal brain vasculature	"any structural anomaly of the blood vessel network of the brain" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Slc26a4^loop/Slc26a4^loop Genetic Background: involves: C3HeB/FeJ
MP:0005065	abnormal neutrophil morphology	"structural anomaly of the granular leukocytes that have a three- to five-lobed nucleus and a cytoplasm that contains inconspicuous granules stainable by neutral dyes" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Kdm6a^tm1.2Afst/Kdm6a^tm1.2Afst Genetic Background: involves: 129S1/Sv * 129X1/SvJ * BALB/c * C57BL/6 Allelic Composition: Myh9^{tm1.1(MYH9)Mjk}/Myh9^{tm1.1(MYH9)Mjk} Genetic Background: B6.129-Myh9^{tm1.1(MYH9)Mjk} Allelic Composition:* Myh9^tm7.1Rsad/Myh9⁺ Genetic Background: involves: BALB/cJ Allelic Composition: Myh9^tm7.1Rsad/Myh9^tm7.1Rsad Genetic Background: involves: BALB/cJ Allelic Composition: Myh9^{tm6.1(EGFP/MYH9)Rsad}/Myh9⁺ Genetic Background:* involves: 129S4/SvJae * BALB/cJ * C57BL/6
MP:0005161	hematuria	"presence of blood in the urine" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:78193]	Show Allelic Composition: Ttn^tm1.1Hgra/Ttn^tm1.1Hgra Genetic Background: involves: 129S6/SvEvTac * C57BL/6J
MP:0005165	increased susceptibility to injury	"greater than the normal reaction to trauma, especially that by physical means" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Vhl^tm1Jae/Vhl^tm1Jae,Tg(NPHS2-cre)295Lbh/? Genetic Background: involves: 129S4/SvJae * C57BL/6 * SJL
MP:0005253	abnormal eye physiology	"anomalous function and/or activity of the ocular system or any of its parts" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]	Show Allelic Composition: Kdm6a^tm1.2Afst/Kdm6a^tm1.2Afst Genetic Background: involves: 129S1/Sv * 129X1/SvJ * BALB/c * C57BL/6
MP:0005264	glomerulosclerosis	"hyaline deposits or scarring within the renal glomeruli, often occurring with renal arteriosclerosis or diabetes" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Vhl^tm1Jae/Vhl^tm1Jae,Tg(NPHS2-cre)295Lbh/? Genetic Background: involves: 129S4/SvJae * C57BL/6 * SJL Allelic Composition: Myh9^{tm1.1(MYH9)Mjk}/Myh9^{tm1.1(MYH9)Mjk} Genetic Background: B6.129-Myh9^{tm1.1(MYH9)Mjk} Allelic Composition:* Myh9^tm7.1Rsad/Myh9⁺ Genetic Background: involves: BALB/cJ Allelic Composition: Myh9^tm7.1Rsad/Myh9^tm7.1Rsad Genetic Background: involves: BALB/cJ Allelic Composition: Myh9^tm8.1Rsad/Myh9⁺ Genetic Background: involves: BALB/cJ Allelic Composition: Myh9^tm5Rsad/Myh9^tm5Rsad,Tg(Nphs2-cre)1Seq/0 Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ Allelic Composition: Myh9^tm1.1Dash/Myh9⁺ Genetic Background: involves: 129S2/SvPas * C57BL/6 * C57BL/6J * CBA
MP:0005326	abnormal podocytes	"anomalous structure of the foot processes of the epithelial cells of the glomerulus" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, J:57971]	Show Allelic Composition: Myh9^tm5Rsad/Myh9^tm5Rsad,Tg(Nphs2-cre)1Seq/0 Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ
MP:0005464	abnormal platelet physiology	"atypical response of the non-nucleated cells found in the blood and involved in blood coagulation" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003]	Show Allelic Composition: Map3k5^tm1Hijo/Map3k5^tm1Hijo,Map3k6^tm1Hijo/Map3k6^tm1Hijo Genetic Background: B6.129-Map3k6^tm1Hijo Map3k5^tm1Hijo Allelic Composition: Myh9^tm1.1Gac/Myh9⁺,Tg(Pf4-icre)Q3Rsko/0 Genetic Background: involves: 129 * C57BL/6
MP:0005542	corneal vascularization	"formation of blood vessels in the cornea, which normally lacks vessels" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Myh9^{tm1.1(MYH9)Mjk}/Myh9⁺ Genetic Background:* B6.Cg-Myh9^{tm1.1(MYH9*)Mjk}
MP:0005606	increased bleeding time	"greater than the normal duration of blood flow after skin puncture; indicative of platelet and capillary function" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, RGD:Rat Genome Database submission]	Show Allelic Composition: Map3k5^tm1Hijo/Map3k5^tm1Hijo,Map3k6^tm1Hijo/Map3k6^tm1Hijo Genetic Background: B6.129-Map3k6^tm1Hijo Map3k5^tm1Hijo Allelic Composition: Myh9^{tm1.1(MYH9)Mjk}/Myh9⁺ Genetic Background:* B6.Cg-Myh9^{tm1.1(MYH9)Mjk} Allelic Composition:* Myh9^{tm1.1(MYH9)Mjk}/Myh9^{tm1.1(MYH9)Mjk} Genetic Background: B6.129-Myh9^{tm1.1(MYH9)Mjk} Allelic Composition:* Myh9^tm7.1Rsad/Myh9⁺ Genetic Background: involves: BALB/cJ Allelic Composition: Myh9^tm7.1Rsad/Myh9^tm7.1Rsad Genetic Background: involves: BALB/cJ Allelic Composition: Myh9^{tm6.1(EGFP/MYH9)Rsad}/Myh9⁺ Genetic Background:* involves: 129S4/SvJae * BALB/cJ * C57BL/6
MP:0006325	impaired hearing	"reduced ability to percieve auditory stimuli" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]	Show Allelic Composition: Lepr^tm1.2Chua/Lepr^tm1.2Chua Genetic Background: involves: 129 * C57BL/6
MP:0008079	decreased CD8-positive T cell number	"reduction in the number of the regulatory subset of T lymphocytes that are involved in MHC class I restricted interactions" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Myh9^tm5Rsad/Myh9^tm5Rsad,Tg(Lck-cre)#Nik/0 Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J * DBA/2
MP:0008139	fused podocyte foot processes	"coalescence of the footlike extension of podocytes that interdigitate with one another to form the walls of the glomerular capillaries " [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]	Show Allelic Composition: Vhl^tm1Jae/Vhl^tm1Jae,Tg(NPHS2-cre)295Lbh/? Genetic Background: involves: 129S4/SvJae * C57BL/6 * SJL
MP:0008140	podocyte foot process effacement	"thinning of the footlike extension of podocytes that interdigitate with one another to form the walls of the glomerular capillaries" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]	Show Allelic Composition: Vhl^tm1Jae/Vhl^tm1Jae,Tg(NPHS2-cre)295Lbh/? Genetic Background: involves: 129S4/SvJae * C57BL/6 * SJL Allelic Composition: Myh9^tm5Rsad/Myh9^tm5Rsad,Tg(Nphs2-cre)1Seq/0 Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ Allelic Composition: Myh9^tm1.1Dash/Myh9⁺ Genetic Background: involves: 129S2/SvPas * C57BL/6 * C57BL/6J * CBA
MP:0008254	increased megakaryocyte cell number	"greater number of giant cells 50 to 100 micron in diameter, with a greatly lobulated nucleus, found in the bone marrow; mature blood platelets are released from its cytoplasm" [CL:0000556, ISBN:0721601464]	Show Allelic Composition: Myh9^tm7.1Rsad/Myh9⁺ Genetic Background: involves: BALB/cJ Allelic Composition: Myh9^tm7.1Rsad/Myh9^tm7.1Rsad Genetic Background: involves: BALB/cJ Allelic Composition: Myh9^{tm6.1(EGFP/MYH9)Rsad}/Myh9⁺ Genetic Background:* involves: 129S4/SvJae * BALB/cJ * C57BL/6
MP:0008803	abnormal placental labyrinth vasculature morphology	"any structural anomaly in blood vessels of the layer of the placenta where embryonic and maternal blood vessels interdigitate" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]	Show Allelic Composition: Slc26a4^loop/Slc26a4^loop Genetic Background: involves: C3HeB/FeJ Allelic Composition: Myh9^{tm3(GFP/MYH9/MYH10)Rsad}/Myh9^{tm3(GFP/MYH9/MYH10)Rsad} Genetic Background: involves: 129S4/SvJae * C57BL/6 Allelic Composition: Myh9^{tm4(GFP/MYH10/MYH9)Rsad}/Myh9^{tm4(GFP/MYH10/MYH9)Rsad} Genetic Background: involves: 129S4/SvJae * C57BL/6
MP:0008828	abnormal lymph node cell ratio	"deviation from the standard ratios of lymph node cell subpopulations compared to control samples" [MGI:mberry "Melissa Berry, Genetics Resources Curator"]	Show Allelic Composition: Myh9^tm5Rsad/Myh9^tm5Rsad,Tg(Lck-cre)#Nik/0 Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J * DBA/2
MP:0009763	increased sensitivity to induced morbidity/mortality	"decrease in the amount of an external agent required to cause death or diseased state" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]	Show Allelic Composition: Map3k5^tm1Hijo/Map3k5^tm1Hijo,Map3k6^tm1Hijo/Map3k6^tm1Hijo Genetic Background: B6.129-Map3k6^tm1Hijo Map3k5^tm1Hijo
MP:0011091	complete prenatal lethality	"death of all organisms of a given genotype in a population between fertilization and birth (Mus: approximately E18.5)" [MGI:csmith]	Show Allelic Composition: Clock^tm1.1Rep/Clock^tm1.1Rep Genetic Background: involves: 129S4/SvJae * C57BL/6J Allelic Composition: Myh9^tm1.1Dash/Myh9^tm1.1Dash Genetic Background: involves: 129S2/SvPas * C57BL/6 * CBA
MP:0011096	complete embryonic lethality before somite formation	"death of all organisms of a given genotype in a population between the point of implantation and somite formation (Mus: E4.5 to less than E8)" [MGI:csmith]	Show Allelic Composition: Lepr^tm1.2Chua/Lepr^tm1.2Chua Genetic Background: involves: 129 * C57BL/6 Allelic Composition: Myh9^tm1Maco/Myh9^tm1Maco Genetic Background: involves: 129X1/SvJ
MP:0011098	complete embryonic lethality during organogenesis	"death of all organisms of a given genotype in a population between embryo turning and the completion of organogenesis (Mus: E9 to less than E14)" [MGI:csmith]	Show Allelic Composition: Slc26a4^loop/Slc26a4^loop Genetic Background: involves: C3HeB/FeJ Allelic Composition: Myh9^{tm3(GFP/MYH9/MYH10)Rsad}/Myh9^{tm3(GFP/MYH9/MYH10)Rsad} Genetic Background: involves: 129S4/SvJae * C57BL/6 Allelic Composition: Myh9^{tm4(GFP/MYH10/MYH9)Rsad}/Myh9^{tm4(GFP/MYH10/MYH9)Rsad} Genetic Background: involves: 129S4/SvJae * C57BL/6 Allelic Composition: Myh9^{tm6.1(EGFP/MYH9)Rsad}/Myh9^{tm6.1(EGFP/MYH9)Rsad} Genetic Background: involves: 129S4/SvJae * BALB/cJ * C57BL/6
MP:0011100	complete preweaning lethality	"death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]	Show Allelic Composition: Myh9^tm1.1Dash/Myh9⁺ Genetic Background: involves: 129S2/SvPas * C57BL/6 * C57BL/6J * CBA
MP:0011186	abnormal visceral endoderm morphology	"any structural anomaly of the primitive endoderm-derived tissue which remains in contact with and surrounds the extra-embryonic ectoderm and the epiblast and provides signals for the differentiation and patterning of the epiblast; a small number of visceral endoderm cells also contribute to the endoderm of the embryonic gut" [PMID:21123814]	Show Allelic Composition: Myh9^tm1Maco/Myh9^tm1Maco Genetic Background: involves: 129X1/SvJ
MP:0011402	renal cast	"any of the various casts formed from gelled protein precipitated in the distal convoluted tubules and collecting ducts of nephrons and molded to the tubular or duct lumen which dislodge and pass into the urine; types named for their constituent material include acellular casts (e.g. granular, hyaline, waxy, or fatty casts) and cellular casts (e.g. red or white blood cell casts)" [MGI:anna]	Show Allelic Composition: Vhl^tm1Jae/Vhl^tm1Jae,Tg(NPHS2-cre)295Lbh/? Genetic Background: involves: 129S4/SvJae * C57BL/6 * SJL
MP:0011409	increased renal glomerulus basement membrane thickness	"increased width of the layer of extracellular matrix that lies between the endothelium of the glomerular capillaries and the podocytes of the inner or visceral layer of the Bowman capsule" [MGI:anna]	Show Allelic Composition: Vhl^tm1Jae/Vhl^tm1Jae,Tg(NPHS2-cre)295Lbh/? Genetic Background: involves: 129S4/SvJae * C57BL/6 * SJL
MP:0011523	thin placenta labyrinth	"decrease in the width of the structure where embryonic blood vessels are surrounded by trophoblast cells and maternal blood" [MGI:csmith]	Show Allelic Composition: Myh9^{tm3(GFP/MYH9/MYH10)Rsad}/Myh9^{tm3(GFP/MYH9/MYH10)Rsad} Genetic Background: involves: 129S4/SvJae * C57BL/6
MP:0011525	abnormal placenta intervillous maternal lacunae morphology	"any structural anomaly of the spaces of the placenta occupied by maternal blood, into which the fetal labyrinth villi project" [MGI:csmith]	Show Allelic Composition: Myh9^{tm6.1(EGFP/MYH9)Rsad}/Myh9^{tm6.1(EGFP/MYH9)Rsad} Genetic Background: involves: 129S4/SvJae * BALB/cJ * C57BL/6
MP:0011526	abnormal placenta fetal blood space morphology	"any structural anomaly of the spaces of the placenta occupied by fetal blood, primarily within the fetal labyrinth villi" [MGI:csmith]	Show Allelic Composition: Myh9^{tm6.1(EGFP/MYH9)Rsad}/Myh9^{tm6.1(EGFP/MYH9)Rsad} Genetic Background: involves: 129S4/SvJae * BALB/cJ * C57BL/6
MP:0011868	podocyte microvillus transformation	"aberrant formation of numerous slender cellular projections resembling microvilli or vesicle-like structures along the apical surface of podocytes, suggestive of podocyte injury" [MGI:anna]	Show Allelic Composition: Vhl^tm1Jae/Vhl^tm1Jae,Tg(NPHS2-cre)295Lbh/? Genetic Background: involves: 129S4/SvJae * C57BL/6 * SJL
MP:0011967	increased or absent threshold for auditory brainstem response	"increase in the value at which one or more sound frequencies or broadband clicks first elicits a recordable response generated by electrical activity of neurons in the ascending auditory system, or complete lack of a recordable response at any frequency or broadband click" [MGI:csmith]	Show Allelic Composition: Lepr^tm1.2Chua/Lepr^tm1.2Chua Genetic Background: involves: 129 * C57BL/6 Allelic Composition: Myh9^{tm1.1(MYH9)Mjk}/Myh9⁺ Genetic Background:* B6.Cg-Myh9^{tm1.1(MYH9)Mjk} Allelic Composition:* Myh9^tm1.1Dash/Myh9⁺ Genetic Background: involves: 129S2/SvPas * C57BL/6 * C57BL/6J * CBA

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		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr

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