ENSDARG00000063295


Danio rerio

Features
Gene ID: ENSDARG00000063295
  
Biological name :myh9a
  
Synonyms : myh9a / myosin, heavy chain 9a, non-muscle
  
Possible biological names infered from orthology : MYH9 / myosin heavy chain 9 / myosin, heavy polypeptide 9, non-muscle / P35579 / Q8VDD5
  
Species: Danio rerio
  
Chr. number: 6
Strand: -1
Band:
Gene start: 7735806
Gene end: 7776612
  
Corresponding Affymetrix probe sets: Dr.9044.1.A1_at (Zebrafish Array)   Dr.9531.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000155459
Ensembl peptide - ENSDARP00000096003
Ensembl peptide - ENSDARP00000124366
Ensembl peptide - ENSDARP00000150232
NCBI entrez gene - 333938     See in Manteia.
RefSeq - NM_001098177
RefSeq - XM_005165694
RefSeq - XM_005165695
RefSeq Peptide - NP_001091647
swissprot - F1R889
swissprot - A4VCF3
swissprot - F8W3L6
ZFIN ID - ZDB-GENE-030131-5870
Ensembl - ENSDARG00000063295
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 MYH9ENSGALG00000043092Gallus gallus
 MYH9ENSG00000100345Homo sapiens
 Myh9ENSMUSG00000022443Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
myh9b / myosin, heavy chain 9b, non-muscle / MYH9* / P35579* / Q8VDD5* / myosin heavy chain 9* / myosin, heavy polypeptide 9, non-muscle*ENSDARG0000000101473
myh10 / myosin, heavy chain 10, non-muscle / Q61879* / P35580* / Myosin-10 * / myosin heavy chain 10*ENSDARG0000000010372
myh11a / myosin, heavy chain 11a, smooth muscle / MYH11* / P35749* / myosin heavy chain 11*ENSDARG0000000978269
myh14 / myosin, heavy chain 14, non-muscle / Q7Z406* / Q6URW6* / Myosin-14 * / myosin heavy chain 14*ENSDARG0000007373261
myh11b / myosin, heavy chain 11b, smooth muscle / MYH11* / P35749* / myosin heavy chain 11*ENSDARG0000010097261
smyhc2 / slow myosin heavy chain 2 / MYH7* / MYH6* / P12883* / P13533* / myosin heavy chain 7* / myosin heavy chain 6*ENSDARG0000011403139
smyhc2 / slow myosin heavy chain 2 / MYH7* / MYH6* / P12883* / P13533* / myosin heavy chain 7* / myosin heavy chain 6*ENSDARG0000010396939
myh7l / myosin heavy chain 7-like / MYH6* / MYH7* / Q91Z83* / P12883* / P13533* / Q02566* / Myosin-7 * / myosin heavy chain 7* / myosin heavy chain 6* / myosin, heavy polypeptide 6, cardiac...ENSDARG0000007978239
CU633479.2 / MYH6* / MYH7* / P13533* / P12883* / myosin heavy chain 6* / myosin heavy chain 7*ENSDARG0000010383739
smyhc1 / slow myosin heavy chain 1 / MYH7* / MYH6* / P12883* / P13533* / myosin heavy chain 7* / myosin heavy chain 6*ENSDARG0000009995939
myh7ba / myosin, heavy chain 7B, cardiac muscle, beta a / MYH7B* / A7E2Y1* / A2AQP0* / Myosin-7B * / myosin heavy chain 7B*ENSDARG0000007607539
myh7 / myosin heavy chain 7 / MYH6* / Q91Z83* / P12883* / P13533* / Q02566* / Myosin-7 * / myosin heavy chain 6* / myosin, heavy polypeptide 6, cardiac muscle, alpha*ENSDARG0000007956439
myhz1.3 / myosin, heavy polypeptide 1.3, skeletal muscle / MYH2* / MYH4* / MYH8* / MYH1* / MYH13* / Q9Y623* / P12882* / P13535* / P13542* / Q5SX39* / Q5SX40* / Q9UKX2* / Q9UKX3* / Myosin-1 ...ENSDARG0000006799738
myh7bb / myosin, heavy chain 7B, cardiac muscle, beta b / MYH7B* / A7E2Y1* / A2AQP0* / Myosin-7B * / myosin heavy chain 7B*ENSDARG0000003532238
myh6 / myosin, heavy chain 6, cardiac muscle, alpha / MYH7* / Q91Z83* / P12883* / P13533* / Q02566* / Myosin-7 * / myosin heavy chain 6* / myosin heavy chain 7* / myosin, heavy polypeptide ...ENSDARG0000009063738
myhb / myosin, heavy chain b / MYH2* / MYH4* / MYH8* / MYH1* / MYH13* / Q9Y623* / P12882* / P13535* / P13542* / Q5SX39* / Q5SX40* / Q9UKX2* / Q9UKX3* / Myosin-1 * / Myosin-8 * / Myosin-4 * ...ENSDARG0000000199338
myhz2 / myosin, heavy polypeptide 2, fast muscle specific / MYH2* / MYH4* / MYH8* / MYH1* / MYH13* / Q9Y623* / P12882* / P13535* / P13542* / Q5SX39* / Q5SX40* / Q9UKX2* / Q9UKX3* / Myosin-1...ENSDARG0000001294438
myhz1.1 / myosin, heavy polypeptide 1.1, skeletal muscle / MYH2* / MYH4* / MYH8* / MYH1* / MYH13* / Q9Y623* / P12882* / P13535* / Q9UKX2* / Q9UKX3* / myosin heavy chain 1* / myosin heavy ch...ENSDARG0000010241431
CU633479.1 / MYH6* / MYH7* / P13533* / P12883* / myosin heavy chain 6* / myosin heavy chain 7*ENSDARG0000009874730
zgc:66156 / MYH1* / MYH2* / MYH4* / MYH8* / MYH13* / P13535* / Q9UKX2* / Q9UKX3* / Q9Y623* / P12882* / myosin heavy chain 1* / myosin heavy chain 2* / myosin heavy chain 4* / myosin heavy c...ENSDARG0000011228714


Protein motifs (from Interpro)
Interpro ID Name
 IPR000048  IQ motif, EF-hand binding site
 IPR001609  Myosin head, motor domain
 IPR002928  Myosin tail
 IPR004009  Myosin, N-terminal, SH3-like
 IPR008989  Myosin S1 fragment, N-terminal
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0003094 glomerular filtration IMP
 biological_processGO:0007018 microtubule-based movement IEA
 biological_processGO:0032835 glomerulus development IMP
 biological_processGO:0032836 glomerular basement membrane development IMP
 biological_processGO:0072015 glomerular visceral epithelial cell development IMP
 biological_processGO:0072104 glomerular capillary formation IMP
 cellular_componentGO:0016459 myosin complex IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003774 motor activity IEA
 molecular_functionGO:0003777 microtubule motor activity IEA
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008017 microtubule binding IEA
 molecular_functionGO:0051015 actin filament binding IEA


Pathways (from Reactome)
Pathway description
Regulation of actin dynamics for phagocytic cup formation
RHO GTPases activate PAKs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000014 dorsal aorta dorsal aorta distended , abnormal
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 ZFA:0000042 midbrain hindbrain boundary midbrain hindbrain boundary cell increased length , abnormal
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 ZFA:0000054 pericardium pericardium edematous , abnormal
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 ZFA:0000084 yolk yolk edematous , abnormal
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 ZFA:0000107 eye eye morphology , abnormal
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 ZFA:0000114 heart heart morphology , abnormal
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 ZFA:0000151 pronephros pronephros renal glomerulus malformed , abnormal
pronephros capillary loop nephron decreased amount , abnormal
pronephros capillary loop nephron closure incomplete , abnormal
pronephros mesangial cell decreased amount , abnormal
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 ZFA:0000155 somite somite morphology , abnormal
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 ZFA:0001094 whole organism whole organism curved dorsal , abnormal
whole organism dorsal-ventral axis decreased length , abnormal
whole organism edematous , abnormal
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 ZFA:0001117 post-vent region post-vent region curved , abnormal
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 ZFA:0001288 renal glomerulus renal glomerulus microvillus protruding into renal capsular space , abnormal
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 ZFA:0001557 pronephric glomerulus pronephric glomerulus morphology , abnormal
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 ZFA:0001673 pronephric podocyte pronephric podocyte attached to dorsal aorta , abnormal
pronephric podocyte cell projection inserted into pronephric capsular space , abnormal
pronephric podocyte cell projection folded , abnormal
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 ZFA:0005285 glomerular basement membrane glomerular basement membrane increased thickness , abnormal
glomerular basement membrane podocyte foot morphology , abnormal
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 ZFA:0005286 lamina densa lamina densa surrounding pronephric podocyte cell projection, abnormal
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 ZFA:0005313 pronephric glomerular basement membrane pronephric glomerular basement membrane increased thickness , abnormal
pronephric glomerular basement membrane decreased permeability , abnormal
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 ZFA:0009285 podocyte podocyte disorganized , abnormal
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 ZFA:0009306 neuroepithelial cell neuroepithelial cell actin filament decreased accumulation midbrain hindbrain boundary apical region, abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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