Manteia

ENSDARG00000099959

Danio rerio

Features

Gene ID:	ENSDARG00000099959

Biological name :	smyhc1

Synonyms :	slow myosin heavy chain 1 / smyhc1

Possible biological names infered from orthology :	MYH6 / MYH7 / Myosin-7 / myosin heavy chain 6 / myosin heavy chain 7 / myosin, heavy polypeptide 6, cardiac muscle, alpha / P12883 / P13533 / Q02566 / Q91Z83

Species:	Danio rerio

Chr. number:	24
Strand:	-1
Band:
Gene start:	40656510
Gene end:	40668208

Corresponding Affymetrix probe sets:	Dr.4200.1.A1_at (Zebrafish Array) NM_001020507_at (Zebrafish Genome Array with custom cdf files)

Cross references:	Ensembl peptide - ENSDARP00000135954 Ensembl peptide - ENSDARP00000139007 NCBI entrez gene - 321552 See in Manteia. RefSeq - NM_001020507 RefSeq - XM_005162920 RefSeq Peptide - NP_001018343 swissprot - A0A0R4IVW7 swissprot - A0A0R4INI3 ZFIN ID - ZDB-GENE-030131-271 Ensembl - ENSDARG00000099959

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Ortholog name	ID	Species
MYH7	ENSGALG00000035594	Gallus gallus
MYH6	ENSG00000197616	Homo sapiens
MYH7	ENSG00000092054	Homo sapiens
Myh6	ENSMUSG00000040752	Mus musculus
Myh7	ENSMUSG00000053093	Mus musculus

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
smyhc2 / slow myosin heavy chain 2 / MYH7* / MYH6* / P12883* / P13533* / myosin heavy chain 7* / myosin heavy chain 6*	ENSDARG00000103969	96
smyhc2 / slow myosin heavy chain 2 / MYH7* / MYH6* / P12883* / P13533* / myosin heavy chain 7* / myosin heavy chain 6*	ENSDARG00000114031	93
CU633479.2 / MYH6* / MYH7* / P13533* / P12883* / myosin heavy chain 6* / myosin heavy chain 7*	ENSDARG00000103837	92
myh7 / myosin heavy chain 7 / MYH6* / Q91Z83* / P12883* / P13533* / Q02566* / Myosin-7 * / myosin heavy chain 6* / myosin, heavy polypeptide 6, cardiac muscle, alpha*	ENSDARG00000079564	90
myh7l / myosin heavy chain 7-like / MYH6* / MYH7* / Q91Z83* / P12883* / P13533* / Q02566* / Myosin-7 * / myosin heavy chain 7* / myosin heavy chain 6* / myosin, heavy polypeptide 6, cardiac...	ENSDARG00000079782	88
myh6 / myosin, heavy chain 6, cardiac muscle, alpha / MYH7* / Q91Z83* / P12883* / P13533* / Q02566* / Myosin-7 * / myosin heavy chain 6* / myosin heavy chain 7* / myosin, heavy polypeptide ...	ENSDARG00000090637	84
myhz2 / myosin, heavy polypeptide 2, fast muscle specific / MYH2* / MYH4* / MYH8* / MYH1* / MYH13* / Q9Y623* / P12882* / P13535* / P13542* / Q5SX39* / Q5SX40* / Q9UKX2* / Q9UKX3* / Myosin-1...	ENSDARG00000012944	79
myhb / myosin, heavy chain b / MYH2* / MYH4* / MYH8* / MYH1* / MYH13* / Q9Y623* / P12882* / P13535* / P13542* / Q5SX39* / Q5SX40* / Q9UKX2* / Q9UKX3* / Myosin-1 * / Myosin-8 * / Myosin-4 * ...	ENSDARG00000001993	79
myhz1.3 / myosin, heavy polypeptide 1.3, skeletal muscle / MYH2* / MYH4* / MYH8* / MYH1* / MYH13* / Q9Y623* / P12882* / P13535* / P13542* / Q5SX39* / Q5SX40* / Q9UKX2* / Q9UKX3* / Myosin-1 ...	ENSDARG00000067997	79
myh7ba / myosin, heavy chain 7B, cardiac muscle, beta a / MYH7B* / A7E2Y1* / A2AQP0* / Myosin-7B * / myosin heavy chain 7B*	ENSDARG00000076075	73
myh7bb / myosin, heavy chain 7B, cardiac muscle, beta b / MYH7B* / A7E2Y1* / A2AQP0* / Myosin-7B * / myosin heavy chain 7B*	ENSDARG00000035322	70
myhz1.1 / myosin, heavy polypeptide 1.1, skeletal muscle / MYH2* / MYH4* / MYH8* / MYH1* / MYH13* / Q9Y623* / P12882* / P13535* / Q9UKX2* / Q9UKX3* / myosin heavy chain 1* / myosin heavy ch...	ENSDARG00000102414	68
CU633479.1 / MYH6* / MYH7* / P13533* / P12883* / myosin heavy chain 6* / myosin heavy chain 7*	ENSDARG00000098747	67
myh11a / myosin, heavy chain 11a, smooth muscle / MYH11* / P35749* / myosin heavy chain 11*	ENSDARG00000009782	40
myh10 / myosin, heavy chain 10, non-muscle / Q61879* / P35580* / Myosin-10 * / myosin heavy chain 10*	ENSDARG00000000103	39
myh9a / myosin, heavy chain 9a, non-muscle / MYH9* / P35579* / Q8VDD5* / myosin heavy chain 9* / myosin, heavy polypeptide 9, non-muscle*	ENSDARG00000063295	39
myh14 / myosin, heavy chain 14, non-muscle / Q7Z406* / Q6URW6* / Myosin-14 * / myosin heavy chain 14*	ENSDARG00000073732	38
myh11b / myosin, heavy chain 11b, smooth muscle / MYH11* / P35749* / myosin heavy chain 11*	ENSDARG00000100972	37
myh9b / myosin, heavy chain 9b, non-muscle / MYH9* / P35579* / Q8VDD5* / myosin heavy chain 9* / myosin, heavy polypeptide 9, non-muscle*	ENSDARG00000001014	36
zgc:66156 / MYH1* / MYH2* / MYH4* / MYH8* / MYH13* / P13535* / Q9UKX2* / Q9UKX3* / Q9Y623* / P12882* / myosin heavy chain 1* / myosin heavy chain 2* / myosin heavy chain 4* / myosin heavy c...	ENSDARG00000112287	22

Protein motifs (from Interpro)

Interpro ID	Name
IPR000048	IQ motif, EF-hand binding site
IPR001609	Myosin head, motor domain
IPR002928	Myosin tail
IPR004009	Myosin, N-terminal, SH3-like
IPR027417	P-loop containing nucleoside triphosphate hydrolase

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0007018	microtubule-based movement	IEA
biological_process	GO:0030240	skeletal muscle thin filament assembly	IMP
biological_process	GO:0031444	slow-twitch skeletal muscle fiber contraction	IGI
biological_process	GO:0071688	striated muscle myosin thick filament assembly	IMP
cellular_component	GO:0016459	myosin complex	IEA
molecular_function	GO:0000166	nucleotide binding	IEA
molecular_function	GO:0003774	motor activity	IEA
molecular_function	GO:0003777	microtubule motor activity	IEA
molecular_function	GO:0003779	actin binding	IEA
molecular_function	GO:0005524	ATP binding	IEA
molecular_function	GO:0008017	microtubule binding	IEA
molecular_function	GO:0051015	actin filament binding	IEA

Pathways (from Reactome)

Pathway description

Striated Muscle Contraction

Phenotype (from MGI, Zfin or HPO)

ID	Phenotype	Definition	Genetic BG
ZFA:0001094	whole organism	whole organism paralysed , abnormal	Show
ZFA:0005277	skeletal muscle	skeletal muscle Z disc disorganized , abnormal	Show
ZFA:0009116	slow muscle cell	slow muscle cell striated muscle myosin thick filament disorganized , abnormal slow muscle cell striated muscle thin filament disorganized , abnormal	Show

Interacting proteins (from Reactome)

Interactor ID

Name

Interaction type

No match

1 s.

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		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr