ENSMUSG00000090841


Mus musculus

Features
Gene ID: ENSMUSG00000090841
  
Biological name :Myl6
  
Synonyms : Myl6 / myosin, light polypeptide 6, alkali, smooth muscle and non-muscle / Q60605
  
Possible biological names infered from orthology : myosin light chain 6 / P60660
  
Species: Mus musculus
  
Chr. number: 10
Strand: -1
Band: D3
Gene start: 128490860
Gene end: 128494145
  
Corresponding Affymetrix probe sets: 10354372 (MoGene1.0st)   10373396 (MoGene1.0st)   10420011 (MoGene1.0st)   10503399 (MoGene1.0st)   10581308 (MoGene1.0st)   10592847 (MoGene1.0st)   1424269_a_at (Mouse Genome 430 2.0 Array)   1434396_a_at (Mouse Genome 430 2.0 Array)   1435041_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000151250
Ensembl peptide - ENSMUSP00000151693
Ensembl peptide - ENSMUSP00000151991
Ensembl peptide - ENSMUSP00000151915
Ensembl peptide - ENSMUSP00000151914
Ensembl peptide - ENSMUSP00000151786
Ensembl peptide - ENSMUSP00000128803
Ensembl peptide - ENSMUSP00000151236
NCBI entrez gene - 17904     See in Manteia.
MGI - MGI:109318
RefSeq - XM_006513323
RefSeq - NM_001317217
RefSeq - NM_001317218
RefSeq - NM_001317219
RefSeq - NM_001317220
RefSeq - NM_010860
RefSeq Peptide - NP_001304149
RefSeq Peptide - NP_001304146
RefSeq Peptide - NP_001304147
RefSeq Peptide - NP_001304148
RefSeq Peptide - NP_034990
swissprot - A0A1W2P6G5
swissprot - A0A1W2P6F6
swissprot - A0A1W2P888
swissprot - Q60605
swissprot - Q642K0
swissprot - A0A1W2P8F0
swissprot - A0A1W2P7Q9
Ensembl - ENSMUSG00000090841
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 myl6ENSDARG00000008494Danio rerio
 zgc:153867ENSDARG00000033738Danio rerio
 MYL6ENSGALG00000035086Gallus gallus
 MYL6ENSG00000092841Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Myl6b / Q8CI43 / Myosin light chain 6B / P14649*ENSMUSG0000003982475
Myl4 / Mus musculus myosin, light polypeptide 4 (Myl4), transcript variant 2, mRNA. / P12829* / myosin light chain 4*ENSMUSG0000006108671
Myl3 / P09542 / Myosin light chain 3 / P08590*ENSMUSG0000005974171
Myl1 / P05977 / Myosin light chain 1/3, skeletal muscle isoform / P05976* / myosin light chain 1*ENSMUSG0000006181669


Protein motifs (from Interpro)
Interpro ID Name
 IPR002048  EF-hand domain
 IPR011992  EF-hand domain pair


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006936 muscle contraction TAS
 biological_processGO:0007519 skeletal muscle tissue development TAS
 biological_processGO:0030049 muscle filament sliding TAS
 cellular_componentGO:0005903 brush border ISO
 cellular_componentGO:0016459 myosin complex TAS
 cellular_componentGO:0016461 unconventional myosin complex IDA
 cellular_componentGO:0031012 extracellular matrix ISO
 molecular_functionGO:0003774 motor activity TAS
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008307 structural constituent of muscle TAS
 molecular_functionGO:0030898 actin-dependent ATPase activity ISS


Pathways (from Reactome)
Pathway description
Smooth Muscle Contraction
RHO GTPases activate PAKs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000022781 Pak2 / Q8CIN4 / Serine/threonine-protein kinase PAK 2 PAK-2p27 PAK-2p34 / Q13177* / p21 (RAC1) activated kinase 2*  / reaction
 ENSMUSG00000034868 Myl12b / Q3THE2 / Myosin regulatory light chain 12B / O14950* / myosin light chain 12B*  / complex
 ENSMUSG00000018830 Myh11 / myosin heavy chain 11 / P35749*  / complex
 ENSMUSG00000022443 Myh9 / Q8VDD5 / myosin, heavy polypeptide 9, non-muscle / P35579* / myosin heavy chain 9*  / complex
 ENSMUSG00000020900 Myh10 / Q61879 / Myosin-10 / P35580* / myosin heavy chain 10*  / complex
 ENSMUSG00000030739 Myh14 / Q6URW6 / Myosin-14 / Q7Z406* / myosin heavy chain 14*  / complex
 ENSMUSG00000090841 Myl6 / Q60605 / myosin, light polypeptide 6, alkali, smooth muscle and non-muscle / P60660* / myosin light chain 6*  / complex






 

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