Manteia

ENSGALG00000001183

Gallus gallus

Features

Gene ID:	ENSGALG00000001183

Biological name :	MYH10

Synonyms :	MYH10 / myosin heavy chain 10

Possible biological names infered from orthology :	Myosin-10 / P35580 / Q61879

Species:	Gallus gallus

Chr. number:	18
Strand:	-1
Band:
Gene start:	1762822
Gene end:	1855756

Corresponding Affymetrix probe sets:	Gga.14927.1.S1_at (Chicken Array) Gga.4547.1.S1_at (Chicken Array) Gga.4547.2.S1_a_at (Chicken Array)

Cross references:	Ensembl peptide - ENSGALP00000055628 Ensembl peptide - ENSGALP00000023352 Ensembl peptide - ENSGALP00000043966 Ensembl peptide - ENSGALP00000044619 NCBI entrez gene - 396465 See in Manteia. RefSeq - XM_015295127 RefSeq - NM_205474 RefSeq - XM_015295124 RefSeq - XM_015295125 RefSeq - XM_015295126 RefSeq Peptide - NP_990805 swissprot - Q789A6 swissprot - A0A1D5NW83 swissprot - Q02015 swissprot - Q789A4 Ensembl - ENSGALG00000001183

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Ortholog name	ID	Species
myh10	ENSDARG00000000103	Danio rerio
MYH10	ENSG00000133026	Homo sapiens
Myh10	ENSMUSG00000020900	Mus musculus

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
MYH9 / myosin-9 / P35579* / Q8VDD5* / myosin heavy chain 9* / myosin, heavy polypeptide 9, non-muscle*	ENSGALG00000043092	77
MYH11 / P10587 / Myosin-11 / P35749* / myosin heavy chain 11*	ENSGALG00000006520	75
MYH7B / Gallus gallus myosin, heavy chain 7B, cardiac muscle, beta (MYH7B), mRNA. / A2AQP0* / A7E2Y1* / Myosin-7B * / myosin heavy chain 7B*	ENSGALG00000030985	40
MYH15 / myosin heavy chain, cardiac muscle isoform / Q9Y2K3* / myosin heavy chain 15*	ENSGALG00000015358	40
MYH1F / Gallus gallus myosin, heavy chain 1F, skeletal muscle (MYH1F), mRNA. / MYH1* / MYH2* / MYH4* / MYH8* / Q9Y623* / P12882* / P13535* / P13542* / Q5SX39* / Q5SX40* / Q9UKX2* / Myosin-1...	ENSGALG00000042257	39
MYH1D / Gallus gallus myosin, heavy chain 1D, skeletal muscle (MYH1D), mRNA. / MYH1* / MYH2* / MYH4* / MYH8* / Q9Y623* / P12882* / P13535* / P13542* / Q5SX39* / Q5SX40* / Q9UKX2* / Myosin-1...	ENSGALG00000027323	39
MYH1C / myosin, heavy chain 1C, skeletal muscle / MYH1* / MYH4* / MYH8* / MYH2* / Q9Y623* / P12882* / P13535* / P13542* / Q5SX39* / Q5SX40* / Q9UKX2* / Myosin-4 * / Myosin-8 * / Myosin-1 *...	ENSGALG00000032404	39
MYH7 / myosin-7 / MYH6* / Q91Z83* / P12883* / P13533* / Q02566* / myosin heavy chain 7* / myosin heavy chain 6* / myosin, heavy polypeptide 6, cardiac muscle, alpha*	ENSGALG00000035594	39
MYH1B / MYH1* / MYH2* / MYH4* / MYH8* / Q9Y623* / P12882* / P13535* / P13542* / Q5SX39* / Q5SX40* / Q9UKX2* / Myosin-1 * / Myosin-4 * / Myosin-8 * / myosin heavy chain 1* / myosin heavy cha...	ENSGALG00000039977	39
MYH1G / Gallus gallus myosin, heavy chain 1G, skeletal muscle (MYH1G), mRNA. / MYH1* / MYH2* / MYH4* / MYH8* / Q9Y623* / P12882* / P13535* / P13542* / Q5SX39* / Q5SX40* / Q9UKX2* / Myosin-1...	ENSGALG00000028612	39
MYH1A / myosin, heavy chain 1A, skeletal muscle / MYH1* / MYH4* / MYH8* / MYH2* / Q9Y623* / P12882* / P13535* / P13542* / Q5SX39* / Q5SX40* / Q9UKX2* / Myosin-4 * / Myosin-8 * / Myosin-1 *...	ENSGALG00000037864	39
MYH13 / myosin heavy chain 13 / Q9UKX3*	ENSGALG00000029660	38

Protein motifs (from Interpro)

Interpro ID	Name
IPR000048	IQ motif, EF-hand binding site
IPR001609	Myosin head, motor domain
IPR002928	Myosin tail
IPR004009	Myosin, N-terminal, SH3-like
IPR008989	Myosin S1 fragment, N-terminal
IPR027401	Myosin IQ motif-containing domain superfamily
IPR027417	P-loop containing nucleoside triphosphate hydrolase

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0000281	mitotic cytokinesis	IEA
biological_process	GO:0001701	in utero embryonic development	IEA
biological_process	GO:0001764	neuron migration	IEA
biological_process	GO:0001778	plasma membrane repair	IEA
biological_process	GO:0003279	cardiac septum development	IEA
biological_process	GO:0006887	exocytosis	IEA
biological_process	GO:0006930	substrate-dependent cell migration, cell extension	IEA
biological_process	GO:0007018	microtubule-based movement	IEA
biological_process	GO:0007097	nuclear migration	IEA
biological_process	GO:0007409	axonogenesis	IEA
biological_process	GO:0007411	axon guidance	IEA
biological_process	GO:0007420	brain development	IEA
biological_process	GO:0007507	heart development	IEA
biological_process	GO:0007512	adult heart development	IEA
biological_process	GO:0008283	cell proliferation	IEA
biological_process	GO:0008360	regulation of cell shape	IEA
biological_process	GO:0021592	fourth ventricle development	IEA
biological_process	GO:0021670	lateral ventricle development	IEA
biological_process	GO:0021678	third ventricle development	IEA
biological_process	GO:0021680	cerebellar Purkinje cell layer development	IEA
biological_process	GO:0030036	actin cytoskeleton organization	IEA
biological_process	GO:0030048	actin filament-based movement	IEA
biological_process	GO:0030239	myofibril assembly	IEA
biological_process	GO:0031032	actomyosin structure organization	IEA
biological_process	GO:0031175	neuron projection development	IEA
biological_process	GO:0035904	aorta development	IEA
biological_process	GO:0050714	positive regulation of protein secretion	IEA
biological_process	GO:0050885	neuromuscular process controlling balance	IEA
biological_process	GO:0055003	cardiac myofibril assembly	IEA
biological_process	GO:0055015	ventricular cardiac muscle cell development	IEA
biological_process	GO:0060041	retina development in camera-type eye	IEA
biological_process	GO:0060976	coronary vasculature development	IEA
cellular_component	GO:0001725	stress fiber	IEA
cellular_component	GO:0005737	cytoplasm	IEA
cellular_component	GO:0005819	spindle	IEA
cellular_component	GO:0005829	cytosol	IEA
cellular_component	GO:0005844	polysome	IEA
cellular_component	GO:0005886	plasma membrane	IEA
cellular_component	GO:0005903	brush border	IEA
cellular_component	GO:0005938	cell cortex	IEA
cellular_component	GO:0016459	myosin complex	IEA
cellular_component	GO:0016460	myosin II complex	IEA
cellular_component	GO:0030424	axon	IEA
cellular_component	GO:0030426	growth cone	IEA
cellular_component	GO:0030496	midbody	IEA
cellular_component	GO:0031594	neuromuscular junction	IEA
cellular_component	GO:0032154	cleavage furrow	IEA
cellular_component	GO:0042641	actomyosin	IEA
cellular_component	GO:0043005	neuron projection	IEA
cellular_component	GO:0043025	neuronal cell body	IEA
cellular_component	GO:0043197	dendritic spine	IEA
cellular_component	GO:0097513	myosin II filament	IEA
molecular_function	GO:0000146	microfilament motor activity	IEA
molecular_function	GO:0000166	nucleotide binding	IEA
molecular_function	GO:0003774	motor activity	IEA
molecular_function	GO:0003777	microtubule motor activity	IEA
molecular_function	GO:0003779	actin binding	IEA
molecular_function	GO:0005524	ATP binding	IEA
molecular_function	GO:0008017	microtubule binding	IEA
molecular_function	GO:0016887	ATPase activity	IEA
molecular_function	GO:0030898	actin-dependent ATPase activity	IEA
molecular_function	GO:0035613	RNA stem-loop binding	IEA
molecular_function	GO:0043531	ADP binding	IEA
molecular_function	GO:0048027	mRNA 5"-UTR binding	IEA
molecular_function	GO:0051015	actin filament binding	IEA

Pathways (from Reactome)

Pathway description

RHO GTPases activate PAKs

Phenotype (from MGI, Zfin or HPO)

Phenotype

Definition

Genetic BG

No match

Interacting proteins (from Reactome)

Interactor ID	Name	Interaction type
ENSGALG00000006520	MYH11 / P10587 / Myosin-11 / P35749* / myosin heavy chain 11*	/ complex
ENSGALG00000006426	PAK2 / p21 (RAC1) activated kinase 2 / Q13177* / Q8CIN4* / Serine/threonine-protein kinase PAK 2 PAK-2p27 PAK-2p34*	/ reaction
ENSGALG00000014854	P24032 / MYL12A / Myosin regulatory light chain 2, smooth muscle minor isoform / Q3THE2* / MYL12B* / O14950* / myosin light chain 12B* / Myosin regulatory light chain 12B *	/ complex
ENSGALG00000035086	MYL6 / myosin light chain 6 / P60660* / Q60605* / myosin, light polypeptide 6, alkali, smooth muscle and non-muscle*	/ complex
ENSGALG00000038635	O14950* / Myl12a* / MYL12B* / Q3THE2* / myosin light chain 12B* / Myosin regulatory light chain 12B *	/ complex
ENSGALG00000001183	MYH10 / myosin heavy chain 10 / P35580* / Q61879* / Myosin-10 *	/ complex

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		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr