ENSGALG00000006520


Gallus gallus

Features
Gene ID: ENSGALG00000006520
  
Biological name :MYH11
  
Synonyms : MYH11 / Myosin-11 / P10587
  
Possible biological names infered from orthology : myosin heavy chain 11 / P35749
  
Species: Gallus gallus
  
Chr. number: 14
Strand: -1
Band:
Gene start: 7610019
Gene end: 7666669
  
Corresponding Affymetrix probe sets: Gga.3225.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000010520
Ensembl peptide - ENSGALP00000049019
Ensembl peptide - ENSGALP00000046782
Ensembl peptide - ENSGALP00000046558
NCBI entrez gene - 396211     See in Manteia.
RefSeq - NM_205274
RefSeq - XM_015294141
RefSeq - XM_015294140
RefSeq - XM_015294139
RefSeq Peptide - NP_990605
swissprot - E1BXA5
swissprot - P10587
swissprot - A0A1D5P1M0
swissprot - A0A1D5P287
swissprot - A0A1D5P8H1
Ensembl - ENSGALG00000006520
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 myh11aENSDARG00000009782Danio rerio
 myh11bENSDARG00000100972Danio rerio
 MYH11ENSG00000133392Homo sapiens
 Myh11ENSMUSG00000018830Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MYH9 / myosin-9 / P35579* / Q8VDD5* / myosin heavy chain 9* / myosin, heavy polypeptide 9, non-muscle*ENSGALG0000004309276
MYH10 / myosin heavy chain 10 / P35580* / Q61879* / Myosin-10 *ENSGALG0000000118376
MYH15 / myosin heavy chain, cardiac muscle isoform / Q9Y2K3* / myosin heavy chain 15*ENSGALG0000001535840
MYH1C / myosin, heavy chain 1C, skeletal muscle / MYH1* / MYH4* / MYH8* / MYH2* / Q9Y623* / P12882* / P13535* / P13542* / Q5SX39* / Q5SX40* / Q9UKX2* / Myosin-4 * / Myosin-8 * / Myosin-1 *...ENSGALG0000003240440
MYH1B / MYH1* / MYH2* / MYH4* / MYH8* / Q9Y623* / P12882* / P13535* / P13542* / Q5SX39* / Q5SX40* / Q9UKX2* / Myosin-1 * / Myosin-4 * / Myosin-8 * / myosin heavy chain 1* / myosin heavy cha...ENSGALG0000003997740
MYH7 / myosin-7 / MYH6* / Q91Z83* / P12883* / P13533* / Q02566* / myosin heavy chain 7* / myosin heavy chain 6* / myosin, heavy polypeptide 6, cardiac muscle, alpha*ENSGALG0000003559440
MYH1D / Gallus gallus myosin, heavy chain 1D, skeletal muscle (MYH1D), mRNA. / MYH1* / MYH2* / MYH4* / MYH8* / Q9Y623* / P12882* / P13535* / P13542* / Q5SX39* / Q5SX40* / Q9UKX2* / Myosin-1...ENSGALG0000002732340
MYH7B / Gallus gallus myosin, heavy chain 7B, cardiac muscle, beta (MYH7B), mRNA. / A2AQP0* / A7E2Y1* / Myosin-7B * / myosin heavy chain 7B*ENSGALG0000003098540
MYH1F / Gallus gallus myosin, heavy chain 1F, skeletal muscle (MYH1F), mRNA. / MYH1* / MYH2* / MYH4* / MYH8* / Q9Y623* / P12882* / P13535* / P13542* / Q5SX39* / Q5SX40* / Q9UKX2* / Myosin-1...ENSGALG0000004225740
MYH1A / myosin, heavy chain 1A, skeletal muscle / MYH1* / MYH4* / MYH8* / MYH2* / Q9Y623* / P12882* / P13535* / P13542* / Q5SX39* / Q5SX40* / Q9UKX2* / Myosin-4 * / Myosin-8 * / Myosin-1 *...ENSGALG0000003786440
MYH1G / Gallus gallus myosin, heavy chain 1G, skeletal muscle (MYH1G), mRNA. / MYH1* / MYH2* / MYH4* / MYH8* / Q9Y623* / P12882* / P13535* / P13542* / Q5SX39* / Q5SX40* / Q9UKX2* / Myosin-1...ENSGALG0000002861240
MYH13 / myosin heavy chain 13 / Q9UKX3*ENSGALG0000002966039


Protein motifs (from Interpro)
Interpro ID Name
 IPR000048  IQ motif, EF-hand binding site
 IPR001609  Myosin head, motor domain
 IPR002928  Myosin tail
 IPR004009  Myosin, N-terminal, SH3-like
 IPR027401  Myosin IQ motif-containing domain superfamily
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006939 smooth muscle contraction ISS
 biological_processGO:0007018 microtubule-based movement IEA
 biological_processGO:0030239 myofibril assembly IMP
 biological_processGO:0030241 skeletal muscle myosin thick filament assembly ISS
 biological_processGO:0048251 elastic fiber assembly IEA
 biological_processGO:0048739 cardiac muscle fiber development IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005859 muscle myosin complex IMP
 cellular_componentGO:0016459 myosin complex IEA
 cellular_componentGO:0030016 myofibril IEA
 cellular_componentGO:0032982 myosin filament IEA
 molecular_functionGO:0000146 microfilament motor activity IMP
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0000287 magnesium ion binding IMP
 molecular_functionGO:0003774 motor activity IEA
 molecular_functionGO:0003777 microtubule motor activity IEA
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005516 calmodulin binding IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008017 microtubule binding IEA
 molecular_functionGO:0008307 structural constituent of muscle IEA
 molecular_functionGO:0030898 actin-dependent ATPase activity IMP
 molecular_functionGO:0032027 myosin light chain binding IPI
 molecular_functionGO:0043531 ADP binding IMP
 molecular_functionGO:0045159 myosin II binding IPI
 molecular_functionGO:0046982 protein heterodimerization activity IMP
 molecular_functionGO:0051015 actin filament binding IEA


Pathways (from Reactome)
Pathway description
Smooth Muscle Contraction
RHO GTPases activate PAKs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000006520 MYH11 / P10587 / Myosin-11 / P35749* / myosin heavy chain 11*  / complex
 ENSGALG00000014854 P24032 / MYL12A / Myosin regulatory light chain 2, smooth muscle minor isoform / Q3THE2* / MYL12B* / O14950* / myosin light chain 12B* / Myosin regulatory light chain 12B *  / complex
 ENSGALG00000001793 MYL10 / myosin light chain 10 / Q62082* / Q9BUA6* / Myosin regulatory light chain 10 *  / complex
 ENSGALG00000001183 MYH10 / myosin heavy chain 10 / P35580* / Q61879* / Myosin-10 *  / complex
 ENSGALG00000035086 MYL6 / myosin light chain 6 / P60660* / Q60605* / myosin, light polypeptide 6, alkali, smooth muscle and non-muscle*  / complex
 ENSGALG00000038635 O14950* / Myl12a* / MYL12B* / Q3THE2* / myosin light chain 12B* / Myosin regulatory light chain 12B *  / complex
 ENSGALG00000006426 PAK2 / p21 (RAC1) activated kinase 2 / Q13177* / Q8CIN4* / Serine/threonine-protein kinase PAK 2 PAK-2p27 PAK-2p34*  / reaction






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr