ENSGALG00000014854


Gallus gallus

Features
Gene ID: ENSGALG00000014854
  
Biological name :MYL12A
  
Synonyms : MYL12A / Myosin regulatory light chain 2, smooth muscle minor isoform / P24032
  
Possible biological names infered from orthology : MYL12B / myosin light chain 12B / Myosin regulatory light chain 12B / O14950 / Q3THE2
  
Species: Gallus gallus
  
Chr. number: 2
Strand: -1
Band:
Gene start: 101147492
Gene end: 101175927
  
Corresponding Affymetrix probe sets: Gga.1738.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000058733
Ensembl peptide - ENSGALP00000059802
Ensembl peptide - ENSGALP00000062106
Ensembl peptide - ENSGALP00000030296
Ensembl peptide - ENSGALP00000047948
Ensembl peptide - ENSGALP00000049683
NCBI entrez gene - 107051991     See in Manteia.
NCBI entrez gene - 396284     See in Manteia.
RefSeq - XM_015277948
RefSeq - XM_015282584
RefSeq - NM_205341
RefSeq - XM_015277947
RefSeq Peptide - NP_990672
swissprot - P24032
swissprot - A0A1L1RUU9
Ensembl - ENSGALG00000014854
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 myl12.2ENSDARG00000025326Danio rerio
 MYL12BENSG00000118680Homo sapiens
 Myl12aENSMUSG00000024048Mus musculus
 Myl12bENSMUSG00000034868Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
O14950* / Myl12a* / MYL12B* / Q3THE2* / myosin light chain 12B* / Myosin regulatory light chain 12B *ENSGALG0000003863599
MYL9 / P02612 / Myosin regulatory light chain 2, smooth muscle major isoform / Q9CQ19* / Myosin regulatory light polypeptide 9 *ENSGALG0000002856794
MYL10 / myosin light chain 10 / Q62082* / Q9BUA6* / Myosin regulatory light chain 10 *ENSGALG0000000179353
MYL2 / myosin light chain 2 / P10916* / P51667* / Myosin regulatory light chain 2, ventricular/cardiac muscle isoform *ENSGALG0000000458252


Protein motifs (from Interpro)
Interpro ID Name
 IPR002048  EF-hand domain
 IPR011992  EF-hand domain pair
 IPR015070  DJBP, EF-hand domain
 IPR018247  EF-Hand 1, calcium-binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 cellular_componentGO:0016459 myosin complex IEA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Smooth Muscle Contraction
RHO GTPases activate PAKs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000006520 MYH11 / P10587 / Myosin-11 / P35749* / myosin heavy chain 11*  / complex
 ENSGALG00000006426 PAK2 / p21 (RAC1) activated kinase 2 / Q13177* / Q8CIN4* / Serine/threonine-protein kinase PAK 2 PAK-2p27 PAK-2p34*  / reaction
 ENSGALG00000001793 MYL10 / myosin light chain 10 / Q62082* / Q9BUA6* / Myosin regulatory light chain 10 *  / complex
 ENSGALG00000001183 MYH10 / myosin heavy chain 10 / P35580* / Q61879* / Myosin-10 *  / complex
 ENSGALG00000014854 P24032 / MYL12A / Myosin regulatory light chain 2, smooth muscle minor isoform / Q3THE2* / MYL12B* / O14950* / myosin light chain 12B* / Myosin regulatory light chain 12B *  / complex
 ENSGALG00000035086 MYL6 / myosin light chain 6 / P60660* / Q60605* / myosin, light polypeptide 6, alkali, smooth muscle and non-muscle*  / complex
 ENSGALG00000038635 O14950* / Myl12a* / MYL12B* / Q3THE2* / myosin light chain 12B* / Myosin regulatory light chain 12B *  / complex
 ENSGALG00000010023 CALM2 / P62149 / Calmodulin / Calm3* / CALM1* / P0DP23* / P0DP26* / P0DP27* / P0DP28* / calmodulin 1*  / reaction
 ENSGALG00000011708 MYLK / Gallus gallus myosin light chain kinase (MYLK), transcript variant 1, mRNA. / Q15746* / myosin light chain kinase*  / reaction






 

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