ENSG00000101782


Homo sapiens

Features
Gene ID: ENSG00000101782
  
Biological name :RIOK3
  
Synonyms : O14730 / RIOK3 / RIO kinase 3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 18
Strand: 1
Band: q11.2
Gene start: 23452823
Gene end: 23486603
  
Corresponding Affymetrix probe sets: 202129_s_at (Human Genome U133 Plus 2.0 Array)   202130_at (Human Genome U133 Plus 2.0 Array)   202131_s_at (Human Genome U133 Plus 2.0 Array)   215588_x_at (Human Genome U133 Plus 2.0 Array)   240583_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000463644
Ensembl peptide - ENSP00000463791
Ensembl peptide - ENSP00000463660
Ensembl peptide - ENSP00000341874
Ensembl peptide - ENSP00000462548
NCBI entrez gene - 8780     See in Manteia.
OMIM - 603579
RefSeq - XM_011526243
RefSeq - NM_003831
RefSeq - XM_011526242
RefSeq Peptide - NP_003822
swissprot - J3QQL5
swissprot - B4E1Q4
swissprot - O14730
swissprot - B0YJ89
swissprot - J3QLP4
Ensembl - ENSG00000101782
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 riok3ENSDARG00000042751Danio rerio
 RIOK3ENSGALG00000015004Gallus gallus
 Riok3ENSMUSG00000024404Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
RIOK1 / Q9BRS2 / RIO kinase 1ENSG0000012478430


Protein motifs (from Interpro)
Interpro ID Name
 IPR000687  RIO kinase
 IPR011009  Protein kinase-like domain superfamily
 IPR017406  Serine/threonine-protein kinase Rio3
 IPR018935  RIO kinase, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0006364 rRNA processing TAS
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0007059 chromosome segregation TAS
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0030490 maturation of SSU-rRNA IMP
 biological_processGO:0032463 negative regulation of protein homooligomerization IDA
 biological_processGO:0032728 positive regulation of interferon-beta production IMP
 biological_processGO:0039534 negative regulation of MDA-5 signaling pathway IMP
 biological_processGO:0042254 ribosome biogenesis IEA
 biological_processGO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling IDA
 biological_processGO:0045087 innate immune response IEA
 biological_processGO:0045089 positive regulation of innate immune response IMP
 biological_processGO:0051607 defense response to virus IEA
 biological_processGO:0071359 cellular response to dsRNA IMP
 biological_processGO:0098586 cellular response to virus IMP
 biological_processGO:1990786 cellular response to dsDNA IMP
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0030688 preribosome, small subunit precursor IDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0089720 caspase binding IDA


Pathways (from Reactome)
Pathway description
Major pathway of rRNA processing in the nucleolus and cytosol


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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