ENSG00000102096


Homo sapiens

Features
Gene ID: ENSG00000102096
  
Biological name :PIM2
  
Synonyms : PIM2 / Pim-2 proto-oncogene, serine/threonine kinase / Q9P1W9
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: X
Strand: -1
Band: p11.23
Gene start: 48913182
Gene end: 48919024
  
Corresponding Affymetrix probe sets: 204269_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000365692
Ensembl peptide - ENSP00000410960
NCBI entrez gene - 11040     See in Manteia.
OMIM - 300295
RefSeq - NM_006875
RefSeq Peptide - NP_006866
swissprot - C9J8V9
swissprot - A0A024QYW7
swissprot - Q9P1W9
Ensembl - ENSG00000102096
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Pim2ENSMUSG00000031155Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PIM3 / Q86V86 / Pim-3 proto-oncogene, serine/threonine kinaseENSG0000019835559
PIM1 / P11309 / Pim-1 proto-oncogene, serine/threonine kinaseENSG0000013719355
PASK / Q96RG2 / PAS domain containing serine/threonine kinaseENSG0000011568733


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR017348  Serine/threonine-protein kinase pim-1/2/3
 IPR017441  Protein kinase, ATP binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000082 G1/S transition of mitotic cell cycle IDA
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0007140 male meiotic nuclear division TAS
 biological_processGO:0007346 regulation of mitotic cell cycle IBA
 biological_processGO:0008283 cell proliferation TAS
 biological_processGO:0008285 negative regulation of cell proliferation IDA
 biological_processGO:0008637 apoptotic mitochondrial changes IEA
 biological_processGO:0009615 response to virus IEP
 biological_processGO:0010508 positive regulation of autophagy ISS
 biological_processGO:0016239 positive regulation of macroautophagy IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0032091 negative regulation of protein binding IEA
 biological_processGO:0043066 negative regulation of apoptotic process IDA
 biological_processGO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling ISS
 biological_processGO:0045893 positive regulation of transcription, DNA-templated ISS
 biological_processGO:0046777 protein autophosphorylation IBA
 biological_processGO:0050821 protein stabilization ISS
 cellular_componentGO:0005737 cytoplasm IBA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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